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105 bronchial carcinomas were examined cytochemically by means of air-dried smear preparations (imprint, brush an puncture smears). The novel laser applicator tip described expands the treatment scope of this technique. A prototype magnetic resonance image (MRI)-conditional robot was developed for navigating a high-intensity focused ultrasound (HIFU) system in order to treat prostate cancer transrectally. Preoperative drainage for malignant biliary strictures: is it time for self-expanding metallic stents?

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Platelet aggregation and secretion of 14C-serotonin and platelet factor 4 by soluble and fibrillar collagen, respectively, were studied in human platelet-rich plasma. Drug resistance is one of the most significant challenges in the treatment of various types of malignancies, however most of the experimental and clinical data in multidrug resistance (MDR) has been obtained in leukemias. The distribution of MAP kinase phosphatase-1 in the cerebrospinal fluid-contacting nucleus and its functional contribution to depressive behaviors Whereas DNA repair sites in normal human cells are evenly distributed through the genome, TCR is highly localized at specific chromosomal domains. In female hybrids of the the F1, F2, and F3 generations, both ventricles were found to have bigger size in relation to body weight than in the pure Wistar, whereas only the F3 group was hypertensive.

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The S/T-protein kinases activated by phosphoinositide 3-kinase (PI3K) regulate a myriad of cellular processes. The phenomenon of poor-quality medicines in resource-limited settings is well documented, and field observations reveal similar problems with medical devices (MDs) and in vitro diagnostics (IVDs). Twenty-one out of 27 pairs of designed microsatellite primers were screened out from the microsatellite sequences, and 10 out of the 21 microsatellite loci were used to investigate the genetic diversity of three populations of M. Following resection, recurrent disease was treated with radiotherapy and chemotherapy and then a final resection. Three weeks of continuous AFO-OD use and gait training showed further improvements in walking speed and the spatiotemporal parameters as well as an increase in dorsiflexion angle and plantar flexor moment of the ankle joint of the paretic limb in stance.

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This paper describes the relationship between acting-out behavior, compliance toward social norms, peer friendship choices, and psychiatric diagnosis among adolescent inpatients. With regard to the EU regulation on medicinal products for pediatric use, this could assume increasing importance and contribute to the development of appropriate and safe medicines for children. The effects of alkaline treatment on the mesoporosity development and iron speciation in Fe-MFI zeolites have been investigated.

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Value-based care not likely to end financial squabbles between insurers, providers. Atypical hand infections with Mycobacterium species are uncommon, and Mycobacterium scrofulaceum infections are rare. Diminished drive exhibited stronger performance in differentiating MDD from non-MDD relative to all DSM-IV criteria except depressed mood, reduced interest/pleasure, and impaired concentration/indecisiveness. An action plan to address health inequalities affecting men who have sex with men began this week. Serine hydroxymethyltransferase from Plasmodium vivax is different in substrate specificity from its homologues.

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Concentration, production and absorption of volatile fatty acids in the large intestine Shared filtering processes link attentional and visual short-term memory capacity limits. By use of imaging techniques similar to those for our clinical cohorts, a commercially available anthropomorphic male phantom with metal oxide semiconductor field effect transistor detectors was scanned to obtain absorbed organ doses for conventional fluoroscopy-guided and CTF-guided ESIs. In situ hybridization analysis showed that Msi 1 mRNA has an expression pattern similar to the encoded protein, with positive staining in both nuclei and cytoplasm of ductal, secretory and stromal cells. Implementing the birth policy to village as the grass-roots unit

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EVALUATION OF PULMONARY FUNCTION TESTS IN THE OBJECTIVE DIFFERENTIATION BETWEEN CHRONIC BRONCHITIS AND EMPHYSEMA. ESBL and qnr genes were searched for by PCR amplification, and the PCR products were then subjected to direct sequencing. Although additional studies regarding this technique are needed, we believe that an infrahepatic vena cavocavostomy should be considered to be an alternative technique in carefully selected cases. Hyperphosphorylation correlated with increased SfIAP turnover independent of the E3 ubiquitin-ligase activity of the SfIAP RING, which also regulated IAP stability.

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Interventions targeting suicidal behaviors in adolescents should consider individual differences. This column reviews the literature on important environmental and therapeutic issues in psychiatric hospital design. Knowledge of signal transduction processes has dramatically increased in the past decade, and the basic principles of intracellular signaling are now quite well established. Interestingly, such neuroendocrine influences appear to be part of a bidirectional circuitry, since thymic-derived peptides also regulate the release of hormones from the pituitary and hypothalamus. In this study, expression microarrays were used to monitor the activity of 18,224 cDNA clones in MCF-7 and HepG2 cells exposed to the carcinogen benzo(a)pyrene (BaP) or its non-carcinogenic isomer benzo(e)pyrene (BeP).

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The highest amount applied (2.0 mg/cm(2)) was linked to the lowest confidence intervals. Abnormal translation of portions of the carpus in response to applied force is a commonly used clinical indicator of ligament injury. Fifty-three patients with at least 3 months of nonspecific low back pain were entered into a Pilates therapy or a Back School treatment group, 43 of which completed the study. Probabilistic inference of regularisation in non-rigid registration. In the perfusion range up to 3.4 ml g(-1) min(-1), agreement between (13)NH(3) perfusion obtained with OSEM and FBP was acceptable.

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Transplantation of 100 leukemic cells appears to be insufficient to induce leukemia after 20 weeks. Endometrioid carcinoma of the ovary and endometrium, oxyphilic cell type: a report of nine cases.

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Cornea verticillata supports a diagnosis of Fabry disease in non-classical phenotypes: results from the Dutch cohort and a systematic review. This work shows that the complexity of biofilm formation can be better understood using a multivariate approach that can interpret and rank the importance of different factors being present simultaneously under several different environmental conditions, enabling a better understanding of this complex process. Among the newly discovered peptides, nociceptin or orphanin-FQ (N/OFQ) peptide has attracted considerable attention because of its sequence homology with the opioid peptide family.

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Despite marked advances in surgical skills, anesthesia, and antibiotics, the results remain poor. A case-control study on Finnish conscripts, officers and other military personnel.

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Ephedrine and ephedra in weight loss products and other preparations A total of 434 women with a primary diagnosis of breast cancer were included in this prospective study at a specialist breast unit. Hypoglycaemia due to inadvertent use of oral hypoglycaemic agents is a recognised problem, particularly in cases where family members living in the same household are taking similar medications.

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Qualitative analysis was conducted using rigorous content analysis methods. In this article, Georges Snounou and Hans-Peter Beck discuss the uncertainties in the interpretation of data inherent to the technical limitations of the PCR technique, and the constraints imposed by the biology of the parasite. Proteomics characterization of protein adsorption onto hemodialysis membranes. These nucleotides may have important regulatory role in muscle and non-muscle systems.

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To investigate the best glucose monitoring strategy for maintaining euglycaemia by comparing self-monitoring of blood glucose with continuous glucose monitoring, with or without an alarm function. An immunoaffinity column was used for the purification of alpha-mannosidase from human placenta. Comparison of ileal conduit and transureteroureterostomy with ureterocutaneostomy urinary diversion. Offering chemotherapy and hospice jointly: one solution to hospice underuse.

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Anesthesiologists and those outside of anesthesiology are employing new potent sedative hypnotic agents to accomplish effective pediatric sedation. Postpartum screening for diabetes among Medicaid-eligible South Carolina women with gestational diabetes. Dietary cysteine and other amino acids and stroke incidence in women. Gene targeting of this evolutionarily conserved protein has revealed a non-redundant role in resistance to selected pathogens.

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Collectively, these studies emphasize the importance of c-Rel in lymphocyte proliferation and oncogenesis, and highlight a requirement for c-Rel in establishing an effective humoral immune response. The cofactors Va and VIIIa bind to the platelets and facilitate subsequent binding of factors IXa and Xa to form functional procoagulant complexes. Furthermore, ligand effects are systematically evaluated which provide valuable information about the favourable properties of the ancillary ligands for promoting reductive elimination of trifluoromethylated products from Pd(II) centers. An analytical model for the determination of the permeability in the lacunar-canalicular porosity of bone using cyclic loading is described in this contribution. The results obtained by the two methods were found in good agreement.

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To identify the genotype of Vietnamese isolates of human hepatitis E virus (HEV), phylogenetic analysis was performed for the open reading frame (ORF) 1 and ORF2 nucleotide sequences of the viral genome. Diagnosing interstitial cystitis in women with chronic pelvic pain. The most commonly used model of CT signal formation, assuming monoenergetic x-ray sources with quantum counting detectors obeying simple Poisson statistics, does not reflect the actual physics of CT acquisition.

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Enzymatic hydrolysis of oleuropein from Olea europea (olive) leaf extract and antioxidant activities. Research continues to progress at a rapid rate, and we can expect many drugs to enter the clinical arena within the next few years.

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There was good correlation between the fluorimetric assay and those in which the free tryptophan released by kidney membrane fractions was determined by h.p.l.c. In this study, owners noted a significant number of adverse side effects with erythromycin stearate administration to dogs. Genomic DNA in mouthwash is stable for prolonged periods at room temperature, and the quantity of DNA recovered from this method is more than sufficient for pharmacogenetic studies. Cerebral processing of linguistic and emotional prosody: fMRI studies. The heat-cured polymer gave up water in a greater extent comparing to the cold-cured one.

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Viral vectors are a means by which genes can be delivered to specific sites in the adult central nervous system. Taurine content appears not to depend on osmolarity of the medium. Complete heart block and preserved LV function: does right ventricular pacing site matter? Interestingly, transcripts encoding several cell adhesion proteins rapidly declined following movement of cultures to the dark, which correlated with a dramatic change in cell surface morphology, likely reflecting the complexity of the extracellular matrix.

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The current findings suggest that attentional impairments in FXS at the behavioral level can be traced back to abnormalities in event-related cortical activity. The most common diagnosis of children receiving oxygen was bronchiolitis, and the device used to deliver oxygen most frequently was nasal cannula. Morphometric measures (mean caliper diameter, surface area, and volume) of nonciliated and ciliated bronchiolar cell nuclei, using computer modeling from serial sections, showed a significant decrease in nuclear size for both cell types and a significant increase in cell volume for the nonciliated bronchiolar cell during lung maturation. Career and practice profiles of Alberta medical graduates (1973-85) practising in Alberta.

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Cyclophosphamide pulse therapy and anticoagulation therapy decreased proteinuria and improved renal function. Treatment should be started during this early phase of the disease. We studied the effect of D-glucaro-1,5-lactam on aminoglycoside-induced nephrotoxicity in rats. Initial findings suggest a trend toward less volume loss after mesenchymal stem cell implantation compared with that in age- and sex-matched controls with chronic, stable MCA infarcts, with a significantly greater growth-to-loss ratio in the infarcted tissue.

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MESMER: minimal ensemble solutions to multiple experimental restraints. The expressed product was analyzed by SDS-PAGE and Western blotting.

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Comparison of GBSSIa and GBSSIb activities shows them to have distinct properties. Postoperative GBP or placebo was continued for four days after surgery.

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Review the medical and surgical management of patients with prolactinomas and provide an in-depth appraisal of the role of radiotherapy in the treatment of prolactinomas. Diffuse pulmonary malignant mesothelioma: response to doxorubicin and 5-azacytidine.

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In ninety-eight knees the preoperative pain was adequately relieved and the limb was in physiological valgus alignment. The panel of experts reviewed the pertinent physiological, epidemiologic, and clinical evidence, including primary research articles and recent review articles. Ischemia of the lateral femoral cutaneous nerve during periacetabular osteotomy using Smith-Petersen approach.

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The authors determined 1) cognitive functioning in detoxified alcoholics who had alcohol-related problems for a relatively brief time and 2) relationships between neuropsychological test scores and recent and chronic alcohol consumption patterns, childhood symptoms of hyperactivity/minimal brain dysfunction, and extent of familial alcoholism. We aimed to determine the frequency of falls from height and the related risk factors. The diagnosis relies mainly on a fine analysis of ductal abnormalities on MRCP with thick slices. Deltaclb1,3,4 Deltabud3 cells, which fail to localize Clb2 to the bud neck, also exhibit a Swe1-dependent elongated bud phenotype.

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Conclusions were that neurotic personality structure or psychopathology were not significantly greater in the treatment group than in the comparison groups. Adjacent level load transfer following vertebral augmentation in the cadaveric spine. Evidence suggests that recovery from stroke damage results from the production of new synaptic pathways within surviving brain regions over weeks.

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We demonstrate here that GNL3L is transported into the nucleolus by a novel lysine-rich nucleolar localization signal (NoLS) residing within 1-50 amino acid residues. Complement, circulating immune complexes and central hemodynamics in pulmonary tuberculosis Traffic accidents in Brazil from 1998 to 2010: many changes and few effects.

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Several methods are used to retrieve the principal components of the 31P chemical shielding tensor from variable-temperature 31P NMR spectra of urea phosphate (both static and spinning at the magic angle at low speeds). Therefore, 6-months of exercise training are an important approach in management arterial hypertension and play a protective effect in postmenopausal women.

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Major modifications of the existing elutriation devices include using a variable speed pump, changing the glass column to plastic, and adding screens at the flow inlet for more uniform velocity distribution while making the column shorter. Prediction of high-valent iron K-edge absorption spectra by time-dependent density functional theory. APAP-induced cell death was investigated in a differentiated, transforming growth factor alpha (TGFalpha)-overexpressing, hepatocyte cell line and found to occur at concentrations, and over time frames, relevant to clinical overdose situations.

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The contribution of blood trace elements to these three diseases and the possibilities for prophylaxis of these three diseases are discussed. Immunogenic activity of viral polypeptides of an Indian isolate of infectious bursal disease virus.

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Analysis indicated different temporal patterning in subscale scores prior to competition. Only a minor part of the activity was due to clones which were cross-reactive for both F1-TNP and DBA/2-TNP target cells. The purpose of this study was to investigate the effect of enhanced noradrenergic activity on memory consolidation in humans. Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease. Comparison of bronchoalveolar lavage fluid examination and other diagnostic techniques with the Baermann technique for detection of naturally occurring Aelurostrongylus abstrusus infection in cats.

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Diffuse brain injury complicated by acute subdural hematoma in the rodents: the effect of early or delayed surgical evacuation. pylori do not eliminate the organism, which presents challenges to vaccine development.

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However, the characterisation of the functional properties of HIR-A and HIR-B revealed no difference in their tyrosine kinase activity in vivo. In addition, lower activity was observed in the GG and a higher activity was observed in the diaphragm, as compared to controls. The alpha2M-kallikrein complex had kinin-releasing activity though much less than free plasma kallikrein, relative to esterolytic potency. LATEST OBSERVATIONS ON THE PRESENCE OF POLYPOID CUSHION IN THE LUMEN OF THE COMMON HEPATIC ARTERY. MODIFICATIONS OF THE PHAGOCYTIC INDEX BEFORE AND AFTER SURGICAL TREATMENT OF CERTAIN DISEASES OF THE THYROID GLAND

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We studied the effect of intersignal interval (ISI) on the averaged acoustic reflex in nine young and nine elderly subjects. This study is the first attempt to investigate the relationship between obesity and the older workforce. Distinct nuclear genes for yeast mitochondrial and cytoplasmic methionyl-tRNA synthetases. Traditionally, patients with a GCS of 8 or less are thought to require airway protection.

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On the other hand, the LAP level, identical in preterms and SDB, is lower than in full-term infants but higher than in adults. Measurements just distal to the subchondral plates of the tibia condyles, where the bone structure is predominantly trabecular, proved to give the most consistent results. Outcome tended to be worse in cases with the following features: age less than 9 months at the time of illness, difficult diagnosis, antibiotic treatment before admission, combined treatment with chloramphenicol and ampicillin, and difficulties at home. Although important steps towards obtaining a safe vaccine to prevent amyloid plaque formation have been made, further evaluations and the use of intermediate models are considered a necessity.