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Sequence analysis of two mutants of Sindbis virus defective in the intracellular transport of their glycoproteins. Application of delivery systems in cancer therapy is restricted as a result of the lack of cell specificity of the respective vectors. Sinus histiocytosis with massive lymphadenopathy--a report of eight cases.

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Current status and recent advances in liver transplant using organs donated after cardiac death. We characterized the cells of the AR tumour and those of its AI derivative by flow cytometric analysis of DNA content and karyotypic analysis of metaphase spreads. Here, we demonstrate direct application of these human cell bioassays to the toxicological assessment of a number of industrial solvents that are in common use worldwide. Removal as a consequence of poor surgery was excluded from the study. Isoelectric focusing of the CSF gamma globulins in multiple sclerosis (262 cases) and other neurological diseases (272 cases).

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These observations may indicate that tight-junctions close after eosinophil-migration. Hepatocellular carcinoma: a case of extrahepatic seeding after percutaneous radiofrequency ablation using an expandable needle electrode. The compressive lesion was then dissected and removed with minimal retraction of the dural sac. coli, Salmonella and Shigella strains isolated from three districts in Kenya were investigated for carriage of plasmids. The effects of neonatal saline injections on behaviours in DBA/2 male mice

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Such efficient in vitro glycation of older cortical bone could result from aging-related increase in porosity caused by the loss of mineral content. 36 healthy adult dogs that underwent elective orthopedic surgery on a pelvic limb. Clinical charts of 76 patients who underwent operation under general anesthesia and 76 healthy control subjects with documented results of DNA damage extent in PBMCs from the single-cell gel electrophoresis (SCGE) or comet assay and serum contents of superoxide dismutase (SOD) and malondialdehyde (MDA) from biochemical analyses were reviewed. c-Myc promotes apoptosis by destabilizing mitochondrial integrity, leading to the release of proapoptotic effectors including holocytochrome c.

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There were some interesting developments with regard to therapeutic agents during this period. A much-amplified fluorescence signal was obtained in the presence of traces of the target miRNA.

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Further amount of water was retained by the surface treatment of coating. These results are the first to illustrate the functional significance of the developmental transition in myosin heavy chain composition of an avian slow skeletal muscle, consistent with our previous findings on mammalian muscle.

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BASOPHILIC DEGRANULATION IN ANAPHYLACTOID REACTIONS, PARTICULARLY IN ACQUIRED COLD URTICARIA The field of neuromorphic silicon synapse circuits is revisited and a parsimonious mathematical framework able to describe the dynamics of this class of log-domain circuits in the aggregate and in a systematic manner is proposed. To assess the effect of replacing dietary long-chain triacylglycerols (LCTs) with medium-chain triacylglycerols (MCTs) on body composition in adults. The ratios (frontal/parietal and parietal/striatum) of CMRGlu showed no interval change. These results lend some support to the hypothesis that viral infections and some unknown localized environmental factors play a role in the development of childhood Type 1 diabetes.

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Differences in health services utilization were compared from six months before MBSR to six months following the one-year anniversary of MBSR. When response inhibition was successful in OCD patients, so was the unintentional suppression of the accompanying thought. The results also suggest a possible interaction of cholinergic substances with periportal mast cells. Hemitruncus arteriosus in an asymptomatic young man--diagnostic value of transesophageal echocardiography

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Although localized injection is painful, anesthetics or corticosteroids can relieve symptoms well. During the New Frontiers in Tendon Research meeting, a group of developmental biologists with expertise across musculoskeletal disciplines identified key challenges for the tendon development field. Our in vitro experiments show that both neuron types respond with regular spiking to somatic current injection and that the feedforward and feedback synaptic connections are excitatory, but of different strength and time course. Regional orientation program for the department of clinical neurosciences.

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Time-sequential modulation in expression of growth factors from platelet-rich plasma (PRP) on the chondrocyte cultures. Additionally, increasing the thickness of the nanofiber layer reduced the infiltration of cells into the scaffolds under both static and flow perfusion culture for the specific conditions tested. The Bacillus subtilis bacteriophage PBS2 uracil-DNA glycosylase inhibitor (Ugi) is an acidic protein of 84 amino acids that inactivates uracil-DNA glycosylase from diverse organisms (Wang, Z., and Mosbaugh, D. We derive expressions for the forward problem and for the Jacobian of the measurements, and propose an iterative reconstruction algorithm using a squared error cost function.

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Myocardial 5-HT(4) serotonin (5-HT) receptors are increased and activated in heart failure (HF). Signs, symptoms, and discrete manometric abnormalities of childhood nonulcer dyspepsia resembled those of adult nonulcer dyspepsia. Therefore, single-tooth implants are exposed to an increased risk of failure.

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In the past decade, the treatment of NSCLC has been revolutionized by the discovery of key oncogenic driver mutations and the therapies that specifically target these mutations. None of the 13 lesions from never-tobacco users exhibited p53 mutations.

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We describe an anesthetic technique that assures secure tube placement, rapid intubation, and ready access to the entire face. Bilateral changes in striatal dopamine metabolism after unilateral intracarotid and intrastriatal administration of apomorphine. Repigmentation was significant on the face compared to upper-limbs with pimecrolimus from fourth to seventh month. coli where it produces large amounts of an ovalbumin-like protein.

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Despite extensive MHC class I-restricted frequencies of yeast-specific CD8 T lymphocytes in healthy individuals and the essential role of the cell-mediated immunity in controlling infections, the characteristics and defense mechanisms of antifungal effector cells are still unclear. Brain-dead Fisher rats were treated for 6 hours with either saline or saline plus NOD.

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The clinical impact of bacteremia in complicated acute pyelonephritis. Our findings show that young adult men and women with ABI who have taken part in a transition preparation program experience similarities in organization, continuity, and availability of care, but they experience differences in relational factors (eg, communication, family involvement). Alcohol exposure alters NMDAR function in the bed nucleus of the stria terminalis. These topographic data were compared to those from the previous study of missing stimulus potentials (Simson et al.

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Currently, there is little information correlating the presence of free sulfhydryl to specific cysteine residues. Through this evaluation, biopsy was avoided in 42 of 88 patients, with follow-up mammograms and physical examinations finding no suspicion of malignancy. Vibration receptors showed maintained responses to sinusoidal vibration of the skin up to 600 Hz. Twenty-seven patients with astrocytic tumors underwent diffusion-weighted magnetic resonance imaging with b values of 1000 and 3000 sec/mm(2), and the corresponding ADC maps were calculated (ADC(1000) and ADC(3000), respectively).

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Humoral immunity depends on the germinal centre (GC) reaction during which somatically mutated high-affinity memory B cells and plasma cells are generated. It was found that luminescent monochromatized incoherent radiation causes inhibition of the ultraviolet light-induced hemolysis of erythrocytes comparable to that induced by laser light. The expression of iNOS shows no prognostic value in pharyngeal SCC. The segments with stent were used to evaluate inflammation score and endothelialization score by hematoxylin-eosin staining. These new methods allow the study of important natural phenomena of the lung microvascular functions.

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The detection limits ranged from 0.01 to 0.27 microg g-1, depending on the elements. The development and implementation of a unique system for medical information management are described. After two years, a slight increase in the reported levels of satisfaction could be seen for life as a whole and for five of the eight domains.

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The evaluation of ectodermal dysplasia cases was made by clinical examination and examination of the jaw and facial areas radiologically and on cone-beam 3-dimensional dental tomography (CBCT) images. anisopliae mycelia extract (MYC) proteins that are recognized by mouse serum IgE, (2) to determine if human serum IgE reacts with these proteins, and (3) to determine if these IgE-reactive proteins are found in other fungi.

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The narrative content is divided into 3 sections with critical appraisals of each: definitions and meaning, theoretical views, and research, the latter of which is further subdivided into measurement and findings. A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism. Physical interactions exist between Fur and PhoU and between Fur and EsrC. Normalisation of insulin-like growth factor-I does not improve insulin action in cirrhosis.

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Establishment of a discriminant mathematical model for diagnosis of deficiency-cold syndrome using gene expression profiling. FURTHER MEASUREMENTS OF THE CO2-CONTENT IN ARTIFICIAL CARBONATED BATHS However, the incidental findings of salivary gland stones on intra oral occlusal radiographs can provide useful information in the early diagnosis of the condition, but in the present study no significant relationship was found between the presence of pulp stones and salivary gland stones. These findings support PE as a primary endovascular therapy for patients undergoing lower extremity arterial revascularization. The model simulates: (1) the heterogeneous small scale geometry of the soft tissue/bone-spicule structure in the lesions as determined by histomorphometric measurements of histologic specimens, (2) the small scale spatial distribution of the radiopharmaceutical on the lesion bone spicule surface as determined by autoradiography, and (3) the 186Re beta and conversion electron decay spectrum and the associated charged particle transport within the modeled geometries.

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The effects of CO(2) and air insufflation on residual bowel gas and postprocedure pain were compared. Tumor-initiating cells are resistant to chemotherapy, but how microRNAs play a role in regulating drug resistance of breast tumor-initiating cells (BT-IC) needs to be clarified. Severe thrombocytopenia that could contribute to hemorrhage may also accompany the APS, but this is unusual. It is becoming increasingly evident that peptides can cross the blood-brain barrier.

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Three of the highest-reported concerns for the entire group are issues that could conceivably be controlled by surgical chairpersons and program directors. For the subsequent staining for light and electron microscopy, procedures for plastic embedding, paraffin embedding and cryostat sectioning are presented.

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Radioimmunoimaging of human colon and gastric cancer xenografts by NCC-ST-439 and NCC-ST-433 monoclonal antibodies No statistically significant differences were noted between laser surgery and open procedures with regard to disease specific survival and local control for both T1a and T1b cases.

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A Phase 3 study assessed LNG-IUS 13.5mg use in healthy women with regular menstrual cycles who requested contraception. We evaluated 33 impotent patients and compared the results of the laboratory methods to the initial diagnoses of the psychiatrist and the urologist to determine if the new methods would confirm our initial impressions or uncover different diagnoses.

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In conclusion, these results suggest that Plantaionoside D can inhibit ADR-induced apoptosis in H9C2 cardiac muscle cells via inhibition of ROS generation and NF-kappaB activation. The catalytic turnover of shikimate and ATP into the products shikimate-3-phosphate and ADP, followed by release of ADP, was studied in the crystalline environment. Most patients were aware of both aspects of vulnerability towards social-emotional and cognitive stressors and took various precautions to avoid relapse or to control symptoms.

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versutus was not relieved by cysteine and methionine, indicating that sulfate uptake and sulfur amino acid biosynthesis were not directly affected by sulfamate. The results suggest that there is a greater prevalence of MI in hypertensive type 2 diabetic patients with dyslipidemia than in non-diabetic hypertensive patients in Trinidad. In addition, up-regulation of IFN-gammaR expression in Chlamydia-infected HeLa cells could be blocked either by neutralizing TLRs with anti-TLR2 and/or anti-TLR4 or by inhibiting NF-kappaB transactivation with a proteasome inhibitor. OA expresses in the kidney of SD rats after acute CsA toxicity and mainly expresses in the tubular epithelial cells and renal interstitium. A diverse group of spontaneous and engineered mouse mutants, characterized by a defect of myelin formation, has been intensively studied from the morphological to the molecular level.

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Daptomycin therapy for vancomycin-resistant enterococcal bacteremia: a retrospective case series of 30 patients. Although carbamazepine prolonged reward latency, an index of motivation for food, neither valproic acid nor carbamazepine significantly affected premature responses. Bob measures the phase difference by passive differential phase detection. Rapid memory T-cell reconstitution recapitulating CD45RA-depleted haploidentical transplant graft content in patients with hematologic malignancies. In the medial vestibular nucleus (MVN), the non-N-methyl-D-aspartate (NMDA) subtype of ionotropic glutamate receptors has been reported as operating at synapses between ipsilateral vestibular afferents and neurons.

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Fascinating emerging technologies such as percutaneous aortic and pulmonary valve implantations have been introduced and the first results have been reported. To estimate the effect of intraabdominal pressure and risk factors related to the occurrence of subcutaneous emphysema during laparoscopic surgery.

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The HAI would then be analogues to the aggregation factors identified in marine sponges. Laser micro-dissection (LMD) is a very useful tool that allows the isolation of finite areas from tissue specimens for downstream analysis of RNA and protein. Whereas restorations presented some clinical aspects somewhat compromised after 2 years, the matrix and wedge systems evaluated showed similar clinical performance. Included is a discussion of standard two- and three-dimensional radiation, as well as intensity-modulated radiotherapy, image-guided radiation therapy, stereotactic radiosurgery, and heavy particles.

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Cadmium accumulation and toxicity in the unicellular alga Pseudokirchneriella subcapitata: Influence of metal-binding exudates and exposure time. Neurophysiologic study of 2 cases of hemianesthesia as a result of subcortical lesions. Studies that employed a wide variety of study designs were involved, but all examined interventions where recasts were the key component. The clinical data of 77 patients treated from 1985-1993 were analysed retrospectively. Heparin-like compounds prepared by chemical modification of capsular polysaccharide from E.

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Morphological and Doppler echocardiographic analyses of Cited2(-/-) embryos reveal severe cardiovascular abnormalities, including pulmonic arterial stenosis and ventricular septal defects accompanied by high peak outflow velocities, features of the human congenital cardiac defect termed tetralogy of Fallot. Caries experience and caries predictors--a study of Tanzanian children consuming drinking water with different fluoride concentrations. The proteome of the serine protease prostate-specific antigen (PSA) and its enzymatic properties have been clarified only recently. Retinoic acid was locally applied to presumptive limb regions of chick embryos to find out the earliest time at which the limb pattern can be reprogrammed.

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An analysis of the nature of injury in fractures of the neck of the femur. Flushing disorders are associated with sweating (wet flushes) or without sweating (dry flushes). Quantifying electro/nucleophilicity by partitioning the dual descriptor.

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Questionnaires assessing childhood physical abuse (CPA), childhood incest (CI), and parental alcoholism (ACOA) were completed by 253 college women from introductory psychology classes at a large midwestern university. Effect of methylation of hMLH1 gene promotor on stage tumorigenesis and progression of human gastric cancer Osteoblastic MC3T3-E1 cells were incubated with H(2)O(2) and/or TE, and markers of osteoblast function and oxidative damage were examined. We hypothesized that (1) neointima formation in a rat carotid balloon injury model could be reduced in vivo following targeted ultrasound delivery of rapamycin microbubbles (RMBs), and (2) the addition of dual-mode ultrasound decreases the total amount of drug needed to reduce neointima formation.

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In instillation group, the insulin was directly added into PN and transfused. The meta-biphenyl series of this class exhibits the greatest enzyme inhibition, selectivity and antifungal activity. Plasma hnRNP B1 mRNA may be useful as a potential marker for the detection of NSCLC. We conclude that all these three procedures are effective for treatment of primary or secondary IOOA with minimum side-effects. In this paper, we propose a hybridized method to predict SL pairs of genes.

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To address this issue, we have investigated the expression and regulation of ABCA1 in Caco-2 cells cultured on Transwell as a model, especially focusing on possible polarized expression of ABCA1. The inner membrane had large numbers of irregularly scattered holes. HPLC methods utilizing the fluorogenic reactions allow analytes to be detected at picomole-subfemtomole levels. Further, the kinetics of apoptosis and necrosis induction were also analyzed. The 1.8 A resolution structure of the gamma appendage is presented.

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We report a facile synthetic route for size-controlled preparation of gold nanoparticles. Peptide lt3a is categorized into M1 branch based on the number of residues in the last Cys loop. Unlike MS spectrometry, NMR spectroscopy is quantitative and does not require extra steps for sample preparation, such as separation or derivatization.