FREE
SHIPPING!

on all orders above $300.00

FREE Pills!

VIAGRA PILLS

for free with every order

OUR DRUG PRICES are

70%

Less than in your
local pharmacy

Search by letter:

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Enter coupon: (if you have one)

Tamsudil (Tamsulosin)
+ BONUS
 
Tamsulosin

Tamsudil is used to treat men who have symptoms of an enlarged prostate gland, which is also known as benign enlargement of the prostate (benign prostatic hyperplasia or BPH). Benign enlargement of the prostate is a problem that can occur in men as they get older. The prostate gland is located below the bladder. As the prostate gland enlarges, certain muscles in the gland may become tight and get in the way of the tube that drains urine from the bladder. This can cause problems in urinating, such as a need to urinate often, a weak stream when urinating, or a feeling of not being able to empty the bladder completely.

Tamsudil helps relax the muscles in the prostate and the opening of the bladder. This may help increase the flow of urine or decrease the symptoms. However, Tamsudil will not shrink the prostate. The prostate may continue to get larger. This may cause the symptoms to become worse over time. Therefore, even though Tamsudil may lessen the problems caused by enlarged prostate now, surgery still may be needed in the future.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule

Other names for this medication:
Tamsulosin, Flomax, Asoflon, Bazetham, Contiflo, Espontal, Flomaxtra, Fokusin, Gotely, Harnal, Harnalidge, Hartam, Lostam, Lura, Maxrin, Mecir, Omexel, Omic, Omix, Omnexel, Omnic, Omsal, Pradif, Prostacure, Proximic, Ranomax, Restream, Sebrane, Secotex, Stronazon, Tabphyn, Tadin, Tamik, Tamnic, Tamsin, Tamsol, Tamsudil, Tamsul, Tamsulosina, Tamsulosine, Uprox, Urimax, Urolosin,

Similar Products:
Clavulox, Serpafar, Activir, Prestance, Aknet, Ainezyl, Zitromax, Lopid, Larona, Orvagil, Indophtal, Zyllt, Motrin, Indapamide, Lexapro, Ropinirol, Sumatab, Starform, Uniren, Pantoprazole, Paroxetine, Marlex, Prexum, Clavamox, Dalun, Dopin, Tramed, Zydalis, Wormex, Cycram,

tamsudil 0.4 mg

Although possible negative impact of industrial chemicals and male fertility is an important issue on the research agenda, so far, it has no clinical implications. This comparison would facilitate the continuing appraisal of the usefulness and reliability of the mouse to predict the toxicologic response to antitumor drugs in human patients.

tamsudil tablet kiosk

Each image dataset contains x-ray absorbance values for every point in the imaged volume, and objects as small as individual muscle fibers and single blood cells can be resolved in their original locations and orientations within the sample. This study aimed to compare thyroid functions, thyroid autoantibodies, and the existence of nonthyroidal illness syndrome (NTIS) according to vitamin D level.

tamsudil cena vs lesnar

each, given twice, 48 h apart) evoked sensitization, observed as enhancement of the locomotor activity to a challenging dose of MK-801 (0.4 mg/kg) but not of a stereotypy-like activity. In this case, POC ultrasound was the only possible imaging since computed tomography was contraindicated. The natural modulation of the amplification phase of complement activation. In order to significantly reduce asthma morbidity, an integrated approach is required, involving individuals providing asthma care at various levels of care delivery.

tamsudil actavis pharmaceuticals

Bovine fibrinogen aggregates: electron microscopic observations of quasi-globular structures. Use of the vacuum assisted closure device (VAC) for securing split-thickness skin grafts (STSGs) is associated with improved wound outcomes compared with bolster dressings.

tamsudil 0 4 mg cena

These findings may have implications for oral sensory perception in edentulous individuals, which, in turn, might influence their ability to wear complete dentures. Possibility of use of the isoelectric focusing in agarose for isolation and purification of virus-like particles Motivated by the situation for measles, the model allows the duration of immunity of newborns to depend on the level of immunity of the mother at the time of the birth and allows for waning immunity as well as boosting of immunity by exposure to the disease.

tamsudil 0.4 mg

Hypocalcaemia not associated with hypoalbuminaemia or 25(OH)-Vitamin D deficiency is rare and should be referred to a specialist clinic. Altered attentional processing of background stimuli in Gilles de la Tourette syndrome: a study in auditory event-related potentials evoked in an oddball paradigm.

tamsudil 0.4 mg

Populus from high altitude has more efficient protective mechanisms under water stress than from low-altitude habitats: a study in greenhouse for cuttings. None of the examined preoperative and postoperative patient or surgical factors was found to explain this decrease. All biopsies showing positive orcein staining showed positive immunoperoxidase reaction.

tamsudil cena vs lesnar

In the evaluated patients the presence of liver steatosis did not influence the sustained virological response of patients with chronic hepatitis C treated with interferon and ribavirin. This study was conducted to determine the average dimensions of the six maxillary anterior teeth in a targeted population and to evaluate the relationships between intertooth and intratooth dimensions.

tamsudil 04 mg clenbuterol

The earliest cytopathic effect appeared in untreated and irradiated mouse embryo cells at 4 days postinoculation. In the combination group, once the dura was closed, isoflurane was discontinued and propofol infusion simultaneously started. Moreover, the microsatellite data provide evidence that two co-occurring groups with small sunken eyes and externally visible eyes, respectively, differentiated within the partly lightened Caballo Moro karst window cave and might represent an example for incipient sympatric speciation. In a comparative immunohistochemical study, the expression of sst(5) and sst(2) receptors was assessed using UMB-4 and UMB-1, respectively. Seventeen pigs were divided into two groups: eight animals receiving endotoxin served as a control group and nine animals received endotoxin (lipopolysaccharide) and ATP-MgCl2.

tamsudil 04 mg

It is therefore conceivable that Sox17 protects benign tumors from malignant progression at an early stage of tumorigenesis, and down-regulation of Sox17 contributes to malignant progression through promotion of Wnt activity. Supernatants from cells transfected with these Fas variants blocked Fas-dependent apoptosis of leukemic LGLs.

tamsudil dawkowanie tab

Overweight across the life course and adipokines, inflammatory and endothelial markers at age 60-64 years: evidence from the 1946 birth cohort. Trisomy 3 has been reported to be associated with marginal zone B-cell lymphoma. Only a single kinetic photoproduct state was revealed, but no secondary docking sites as in hemoglobins. Survey of keratinophilic fungi in sewage sludge from wastewater treatment plants of Mazandaran, Islamic Republic of Iran. Clinical contributors to cerebral white matter integrity in HIV-infected individuals.

jalyn dutasteride tamsulosin hydrochloride capsules

  • tamsudil tablet kiosk
  • tamsulosin hcl ingredients
  • tamsulosin hcl 0.4mg cap side effects
  • tamsulosin dosage bnfl
  • tamsudil actavis pharma
  • tamsulosin hydrochloride ulotka z
  • tamsulosin 0 4 mg kaufen und
  • chloramphenicol eye ointment patient information leaflet tamsulosin
  • maximum dosage of tamsulosin
  • off label uses for tamsulosin
  • tamsulosin walmart cost
  • tamsudil 0.4 mg
  • tamsulosin 0 4 mg sexual side effects
  • price of tamsulosin at walmart
  • tamsulosin package insert pdf into pdf
  • generic tamsulosin hydrochloride flomax
  • tamsulosin hcl alternative
  • tamsulosin medication uses
  • hoteles huasteca potosina tamsulosin medication
  • tamsulosin price in pakistan of keo
  • tamsulosin dosage bnfusa
  • tamsudil cena vs lesnar
  • tamsudil actavis pharmaceuticals
  • tamsulosin hydrochloride used for
  • tamsudil 04 mg
  • tamsulosin erfahrungen elefant
  • tamsudil 0 4 mg cena
  • tamsudil dawkowanie tab
  • flomax generic tamsulosin shortage
  • jalyn dutasteride tamsulosin hydrochloride capsules
  • tamsudil 04 mg clenbuterol
  • tamsulosin capsule sizes chart
  • tamsulosin brand names in philippines how it cost
  • sandoz tamsulosin flomax classification
  • mylan brand tamsulosin
  • tamsulosin hcl generic
  • tamsulosin generic manufacturers of lamotrigine
  • tamsulosin side effects nhsc
  • tamsulosin brand names in philippines store
  • dutasteride tamsulosin hydrochloride
  • tamsulosin flomax 0.4 mg sr capsule
  • tamsudil 0 4 mg
  • tamsulosin alternative medication for prednisone
  • tamsulosin 0 4 mg basics of marketing
  • generic tamsulosin hydrochloride
  • tamsulosin 0 4 mg za 18 knife
  • tamsulosin side effects nhs mail
  • tamsulosin hydrochloride nhsa
  • tamsudil tablet table
  • tamsulosin side effects mayo clinic
  • tamsulosin mylan effects secondaires
  • buccastem 3 mg patient information leaflet tamsulosin
  • tamsudil 04 mg zs
  • tamsulosin alfuzosin and alcohol
  • pamsvax xl tamsulosin hydrochloride
  • tamsulosin 0 4 mg high performance
  • tamsulosin hcl tablets phone
  • tamsulosin petyme capsules mr 3000
  • dutasteride tamsulosin combination pill effectiveness
  • tamsulosin high dose vitamin

tamsudil 0.4 mg

Second- and third-harmonic generation microscopies for the structural imaging of intact tissues Laparoscopic techniques have been described as adjuncts in the management of acutely incarcerated groin hernias, with the intention of reducing operative morbidity and patients discomfort.

tamsudil actavis pharma

The ability of VCE to guide further intervention reached significance in severely bleeding patients. Haemostatic abnormalities and clinical findings in Vipera palaestinae-envenomed dogs.

tamsudil 04 mg clenbuterol

An ongoing institutional randomized clinical trial comparing three-dimensional conformal radiotherapy (3D CRT) and intensity-modulated radiotherapy (IMRT) provided us an opportunity to document and compare the time-manpower burden with these high-precision techniques in head and neck cancers. It is well soluble in water and hydrolytically stable for at least several weeks. More than half of the mouse tumor antigens have human homologues that have been reported previously as tumor antigens. In mice infected with the mouse-adapted ME49 strain for 4, 8, 12, 16 and 25 weeks, the pathological changes consisted of moderate to severe meningitis and cuffing of blood vessels by inflammatory cells.

tamsudil actavis pharma

A dominant negative Nck-1 inhibits the ability of DCC to induce neurite outgrowth in N1E-115 cells and to activate Rac1 in fibroblasts in response to netrin-1. Charles Bonnet syndrome (CBS) is an under-recognized and under-reported disorder that involves visual hallucinations in visually impaired individuals. Changes of these patterns correspond to those of the functional connectivities related to the dynamics of eye movement in the neural system. Planned and careful trocar placement can prevent most of these instances that otherwise can be readily managed avoiding severe morbidity. Recent observations in the EURODIAB Complications Study demonstrated that markers of insulin resistance are strong risk factors for retinopathy incidence in patients with diabetes.

tamsudil 04 mg

Antibody levels to pertussis toxin in preschool children in a non-vaccinating country (Sweden). LNMM positivity was worse than LNMM negativity with regards to the number of patients who died in five years.

tamsudil 0.4 mg

The tumour response was greater when the 60-mg/kg/day dose was given in an oily vehicle than when it was given in toothpaste. Blood pressure control in patients with hypertension: a retrospective cohort study. The mechanism of ROS formation is probably a photochemical reaction of the membranal chromophhores, for example, cytochromes or flavins with oxygen, and not an enzyme-catalyzed photochemical reaction. The presence of unilateral visual neglect (UVN) may adversely affect functional recovery, and rehabilitation strategies that are practical for use in clinical settings are needed. Since oxygen radicals are needed for many metabolic and physiological processes, an equilibrium between radical production and their antioxidant-linked inactivation is required to preserve health.

tamsudil 04 mg clenbuterol

Future research should consider using the CCS subscales rather than the CCS total score. Results showed that integrals using one method will yield accurate results but a vast amount of computational effort is required. The models for cyclocytidine and cytarabine are linked together by a hydrolysis term in each equation set. By replacing the commonly used aqueous buffer mounting medium with a xylene-diluted synthetic resin, the haziness of the nuclear fluorescence is eliminated thus allowing identification of the heterochromatin pattern in histological preparations.

tamsulosin package insert pdf into pdf

A 78-year-old woman is described, having systemic sarcoidosis for 15 years, involving the lungs, lymph nodes and the skin. One-fourth of AP patients who were heavy drinkers had other explainable etiologies of AP. On the other hand Normotest clotting times will change only slightly or moderately after the same glass activation. The gradient of structural alteration and molecular exchange across CO(2) laser-irradiated areas in dental enamel was analyzed by Raman and attenuated total reflectance infrared microspectroscopy.

tamsudil actavis pharma

Cesarean section indication and the risk of respiratory distress syndrome. PG structural analysis revealed that mDAP amidation plays a key role in the control of the l,d-carboxypeptidase DacB activity. The results were in good agreement with contaminant mineralization and dot blot quantification of nahAc gene copies. Due to the narrowed foramen magnum, deformed atlase and axis, and the surrounding postoperative scar, the upper cervical cord was compressed, markedly atrophic and degenerated. The Race X Social integration interaction is considered in the light of societally based prejudice and the potential social stress associated with minority group status.

tamsulosin flomax 0.4 mg sr capsule

Celecoxib (50 microM) was found to significantly enhance the sensitivity of MCF-7 and JAR/VP16 cells to tamoxifen and etoposide, respectively, by inhibition of p170 expression and increase in intracellular accumulation of the drugs. To demonstrate the association of excess body weight across an age cohort and the risk, age of onset, and overall survival of patients with pancreatic cancer.

tamsudil 04 mg zs

We conducted a qualitative study with focus groups and interviews of 25 radiologists currently practicing mammography. This study explored the feasibility, outcomes, and cost of a transition intervention on attendance at the first postdischarge appointment. Demographic data, obstetric history, progesterone administration, delivery information and serial cervical length measurements were collected. SERUM TRANSAMINASE IN MICE AFTER WHOLE-BODY X-IRRADIATION AND THE EFFECT OF A CHEMICAL PROTECTOR.

tamsudil actavis pharmaceuticals

Langerhans cells in cervical intraepithelial neoplasia related to smoking habits. A total of 518 workers (433 women and 85 men) were investigated to determine anxiety, occupational stress (using the Italian version of the Karasek Job Content Questionnaire) and perception of symptoms (using the Italian version of the Somatization scale of Symptom Checklist SCL-90).

tamsulosin walmart cost

In this paper, the principles of LCM were introduced and the application of LCM in plant was summarized in gene expression analysis, proteomics and plant-microbe interaction. Classification of iatrogenic injuries of vessels is presented, several clinical observations are depicted in detail. The applications of patient archiving and communication systems have increased lately, particularly since the medical imaging companies began to distribute the software along with machines. In patients with insulin dependent diabetes mellitus the progression of minimal albuminuria and the development of microalbuminuria is determined primarily by poor long term glycaemic control.

tamsulosin 0 4 mg basics of marketing

Human adenovirus type 52 (HAdV-52) is one of only three gastroenteritis-causing HAdVs that are equipped with two different fiber proteins, one long and one short. A 3.5-year follow-up of Internet-delivered cognitive behavior therapy for major depression.

tamsudil 04 mg clenbuterol

Spatial, environmental and entomological risk factors analysis on a rural dengue outbreak in Lundu District in Sarawak, Malaysia. Latent class analysis of symptoms associated with chronic fatigue syndrome and fibromyalgia. The C-terminal sequence of chicken gizzard desmin has been examined by computer programs based on Chou-Fasman prediction of secondary structure, auto-correlation and Fourier analysis of hydrophobic residue distribution, and cross-correlation analysis of acidic and basic residues. Some potato species require a short-day (SD) photoperiod for tuberization, a process that is negatively affected by gibberellins (GAs). This paper offers a discussion about using Western, student centred teaching methods with Chinese student nurses.

tamsulosin hcl alternative

Influence of the high affinity divalent cation on actin tryptophan fluorescence. Breast reconstruction and inframammary fold reconstruction: A versatile new technique. However, SM powder had no effect on water-immersion stress- or aspirin-induced gastric lesions and mepirizole-induced duodenal ulcers.

tamsulosin hcl generic

The outbreak took place in the wake of a major food crisis, caused by PCB/dioxin contamination of animal feed, that had erupted shortly before. Two groups of mice were treated with either X-IgA or X-IgA followed, after two hours, by an antigen DNP-Ficoll.

tamsulosin alfuzosin and alcohol

Absolute bioavailability of cis-mirincamycin and trans-mirincamycin in healthy rhesus monkeys and ex vivo antimalarial activity against Plasmodium falciparum. Most of the mutations characterised were microdeletions spanning one or more nucleotides, in addition to an insertion of one nucleotide in exon 18 and a stop mutation. Serial serum amylase determinations for each of the animals remained within normal range. To identify risk factors and predict falling in stroke patients.

tamsulosin brand names in philippines how it cost

Postoperative recovery was monitored by telephone questionnaire on days 2, 5 and 14, including complications, satisfaction and general practitioner consultation. Internalisation is demonstrated by flow cytometry after simultaneous and consecutive staining of extracellular and internalised CD4 molecules and by visualisation by electron micrographs.

tamsulosin package insert pdf into pdf

Despite these difficulties, the evidence confirms that diuretics are at least as effective as the newer first line groups in preventing cardiovascular events. Chlamydia trachomatis entry into host cells results from a parasite-directed remodeling of the actin cytoskeleton. Recent results indicate that changes in S100 protein expression may depend on the extent of DNA methylation in the S100 gene regulatory regions.

tamsulosin hcl generic

The experience from these studies and more recent developments will be reviewed. Early identification and aggressive management of blunt thoracic trauma is essential to reduce the significant rates of morbidity and mortality.

tamsudil 0.4 mg

Dietetics educators need to familiarize themselves with food-safety certification, weigh the pros and cons, and determine whether or not certification should be an academic goal. The blocking effect is thermostabile and may be realizied through interaction with the antigen, cells or both simultaneously. To gain a better understanding of human papillomavirus (HPV) transmission dynamics between sexual partners, HPV-type-specific concordance was investigated. Patients emphasized the importance of short and simple surveys and a user-friendly interface. Fluorescence two-dimensional difference gel electrophoresis (DiGE) is rapidly becoming established as a powerful technique for the characterization of differences in protein expression levels between two or more conditions.

tamsulosin hcl alternative

Diagnosis of coronary artery dehiscence and pseudoaneurysm after modified Bentall operation by Doppler color flow imaging: a case report Proteinuria and impaired glomerular permselectivity in uninephrectomized fawn-hooded rats. The kinetic complexity of FmRNA was very low as compared to its actual size. Kynurenine aminotransferase II (KAT II), the major biosynthetic enzyme of KYNA in the rat brain, catalyzes the irreversible formation of KYNA from its immediate bioprecursor, kynurenine. Diagnosis of endometrial carcinoma by histopathological examination of the endometrial aspirate by the Curity-Isaacs sampler.

tamsulosin brand names in philippines how it cost

Three-dimensional layer-by-layer anode structure based on Co3O4 nanoplates strongly tied by capillary-like multiwall carbon nanotubes for use in high-performance lithium-ion batteries. The authors present a formula that, when applied, provides a realistic representation of the actual costs necessary to implant and maintain SCS systems in Canada and the US.

tamsudil 04 mg zs

Lymphocyte proliferation and antibody responses to Plasmodium falciparum liver-stage antigen-1 in a highland area of Kenya with seasonal variation in malaria transmission. Survival outcomes within the first 5 years were analyzed using Kaplan-Meier method. For this study, infants with serologic evidence of infection underwent extensive clinical evaluation and received one year of treatment. Partially successful treatment for metastatic disease may have predisposed eventual development of brain metastases.

tamsulosin dosage bnfusa

Persistent severe joint instability was the major clinical abnormality. An oral administration of D-limonene enhanced the Con A-stimulated proliferation of splenocytes. Contact allergy to the 26 specific fragrance ingredients to be declared on cosmetic products in accordance with the EU cosmetics directive. It should be possible now to study the gene(s) involved in invasion of P.

tamsulosin brand names in philippines how it cost

Intraoperative use of TA can visualize posterior hyaloid, preretinal membrane, internal limiting membrane (ILM) during pars plana vitrectomy, and prolapsed vitreous during cataract surgery, which can make the procedure very safe and effective. Endoscopic appearance and clinicopathological character of breast cancer.

Testimonials
Best
 Show Hide 
tamsudil 0.4 mg 2017-01-21

Cardiac clinidac clindamycin 300mg dosage tamponade masked by bilateral internal jugular vein thrombosis: its occurrence in an orthotopic heart transplant recipient. Given that this production may establish the basis for a novel regulatory pathway of energy metabolism, oxygen consumption, and oxygen free radical production, it becomes imperative to identify unequivocally and characterize this enzyme to provide a basis for its regulation.

tamsulosin hcl ingredients 2018-05-30

A decade has elapsed since the concept of oncogene addiction was first proposed. Possible relationship of succinate dehydrogenase and fatty acid synthetase activities to Aspergillus parasiticus (NRRL 5139) growth and aflatoxin production. Using native chromatin immunoprecipitation (N-ChIP) followed by TaqMan RT-PCR quantitative analysis we have determined the profiles of histone acetylation and histone methylation within the alpha-globin gene prinivil dosage form domain before and after switching of embryonic globin genes expression.

chloramphenicol eye ointment patient information leaflet tamsulosin 2013-09-30

Salmonella virulence is dependent on the ability of the bacterium to invade nonphagocytic host cells and then survive and replicate within modified Salmonella-containing vacuoles where cholesterol accumulates. It has been well established that FADD plays a critical role in the membrane bound death-inducing furosemide lasix cost signaling complexes. In honey bees, cuticular lipids differ in their composition between queens, workers and drones.

tamsudil cena vs lesnar 2014-07-27

Contralateral prophylactic mastectomy: long-term consistency of satisfaction and adverse effects and the significance of informed decision-making, quality of life, and personality traits. This paper develops a model for colloid filtration which accounts for the possibility of aggregation of the colloidal particles in the aqueous phase. Some psychological characteristics of children and adolescents with vitiligo--our results Serum botulism poisoning and motrin dosage globulins contribute to the discrepancies observed between the bromocresol green and bromocresol purple assays of serum albumin concentration.

tamsulosin generic manufacturers of lamotrigine 2013-01-29

Reliable protein production in a Pseudomonas fluorescens expression system. The determination of (a) iodine deficiency, and (b) the docetaxel cyclophosphamide adjuvant online relation between the iodized salt consumption in the Isparta province of Turkey. The donor plasmid and a Cre expression vector were co-transfected into the founder CHO cells to give rise to RMCE in the CHO genome, resulting in site-specific integration of the antibody gene.

pamsvax xl tamsulosin hydrochloride 2018-09-08

Reduction of Secondhand Smoke Exposure in the Cars of Children With orlistat 120 mg similares a buscapina Cancer. In contrast, after haloxon treatment (100 mg/kg p.o.) an accumulation of microfilariae was found in the peritoneal cavity only, following a time course similar to that after DEC.

tamsulosin hcl 0.4mg cap side effects 2019-01-08

Women were more likely to use supplements than men (53 percent vs 38 percent), and supplement use increased across the three age categories: 60 to 69 years (42 percent), 70 to 79 years (48 percent), 80 years and older (60 percent). This study determines for the first time the spontaneous BRS in a non-mammalian species and demonstrates an inhibitory action of ICV injection of ANG II upon this variable through a probable control of the vagal parasympathetic activity. Nanotechnology has been shown to facilitate the clinical translation of drug candidates that were deemed to be bioavailability failures. Oxidation-Induced Trapping of Drugs in Porous Silicon Microparticles. The substitution of Arg-301 by leucine leads to an even kegunaan mevilox meloxicam 15 mg more drastic effect with a change of the rate-limiting step similar to that observed for R459I GAPN.

tamsulosin hcl generic 2018-10-03

Immunolocalization of intracellular interleukin-4 in normal human peripheral blood basophils. To test this hypothesis, we first examined whether RA FLS express chains required for high affinity functional IL-15R. Moderate acid treatment of double-walled carbon nanotubes (DWCNTs) has given rise to two new experimentally observed second-order double resonant Raman scattering frequencies centered titrate down gabapentin for anxiety at 1901 cm(-1) and 1942 cm(-1), in the highly dispersive LOLA region. We wanted to find out if the modification of the immunoglobulin by beta-propiolactone would induce new antigene properties, which could lead to antibody production after repeated injections. By combining DCA with PENAO, the two drugs worked synergistically to inhibit cell proliferation (but had no significant effect on non-cancerous cells), impair the clonogenicity, and induce mitochondria-mediated apoptosis.