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Sivastin (Simvastatin)

Sivastin is used together with diet, weight-loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Sivastin is also used to decrease the amount of fatty substances such as low-density lipoprotein (LDL) cholesterol (''bad cholesterol'') and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol (''good cholesterol'') in the blood. Sivastin may also be used to decrease the amount of cholesterol and other fatty substances in the blood in children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Sivastin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats with Sivastin has been shown to prevent heart disease, angina (chest pain), strokes, and heart attacks.

Other names for this medication:
Simvastatin, Zocor, Actalipid, Lipex, Lipinorm, Lodales, Simcard, Simgal, Simvastatina, Simvor, Sinvacor, Sivastin, Vasilip, Zeid, Zocord, Zosta, Zostin,

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Our calculations unify the spin dynamics of both static and fluctuating stripe phases and support the notion of a universal spin excitation spectrum in doped cuprate superconductors. An unusual cause of diarrhea: diffuse intestinal nodular lymphoid hyperplasia in association with selective immunoglobulin A deficiency (with video).

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It is shown that an earlier, less rigorous, but simpler computational technique does not introduce serious errors provided that both a good estimate of the mean energy per photon can be made and the detector does not contain an absorption edge in the spectral range. What is of interest is that the estradiol levels are not altered by any treatment schedule. Studies by our group have shown that passive transfer of autoimmune T cells specific to myelin basic protein (T(MBP)) can protect injured neurons in the rat CNS from secondary degeneration.

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The modified type III composite facial and scalp allograft transplantation model is an ideal model for facial allograft transplantation study. Bone marrow vaccination: a novel approach to enhance antigen specific antitumor immunity. Subtle modification of 2,2-dipicolylamine lowers the affinity and improves the turn-on of Zn(II)-selective fluorescent sensors. New evidence that the intra-uterine growth-retarded piglet is a member of a discrete subpopulation. VCA and MA were readily identified and localized by both procedures without significant modification of the basic techniques.

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The effects of acrylamide on the behavioral suppression produced by psychoactive agents. Patients who were clinically influenced had a higher flow rate and profile changes, whereas pregnancy and menstruation correlated with the predominant changes. Shock wave lithotripsy for ureteral stones in elderly male patients. Sex-specific prevalence of adenomas, advanced adenomas, and colorectal cancer in individuals undergoing screening colonoscopy.

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erinacei were examined pharmacologically using Magnus apparatus and biochemical methods. Plasma modified nanofibres based on gum kondagogu and their use for collection of nanoparticulate silver, gold and platinum.

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These injuries are associated with significant morbidity and financial costs. With or without EBIC using cluster analysis and global evidence, we compared the incidence of postoperative MRSA infection. Ontogeny of MAP kinases in rat small intestine: premature stimulation by insulin of BBM hydrolases is regulated by ERKs but not by p-38 MAP kinase. Demonstration of the anterior surface of the spinal cord is an important step in performing a percutaneous cordotomy. Analysis of cerebellar Purkinje cells using EAAT4 glutamate transporter promoter reporter in mice generated via bacterial artificial chromosome-mediated transgenesis.

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The higher the electric energy applied the greater the nuclear picnosis and more intense the cytoplasmatic shrinkage and electrocoagulation effects. This paper discusses the role of IL-17 in experimental arthritis and its interrelationship with TNF and IL-1, currently the most targeted cytokines in the treatment of RA. In patients with cardiac sustained activation of the immune and neuroendocrine systems and oxidative stress, renal vascular resistance can increase and therefore impair renal perfusion, leading to worsening kidney function. The survey studies analgesic effect of postoperative therapy in two groups of patients with spinal disorders. X100 to 2.2 A resolution: dual conformations for extended inhibitors bound to the active site of glucoamylase.

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Parallel study of the plasma levels of estriol and placental lactogen in women with uncomplicated pregnancy in the last 2 lumar months Difficult-to-control asthma is a frustratingly difficult condition to treat. Patients were instructed to bring their organizers and warfarin tablets to each anticoagulation clinic visit over the following 3 months. Comparison of the cytomorphological classification with the cytochemical differentiation of acute lymphatic leukemia in children Both BjCHI1 and BjCHI2 show in vitro anti-fungal activity toward Trichoderma viride, causing reductions in hyphal diameter, hyphal branching and conidia size.

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Impaired functioning in euthymic patients with bipolar disorder--HSV-1 as a predictor. Usability testing is compared with other types of study designs used in prosthetic research. Of these, 123 procedures were performed for superfluous functional or nonfunctional leads.

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The glutathione content and glutathione-S-transferase activity in the organs and blood of rats following chronic irradiation at low doses Breast reduction for symptomatic macromastia: can objective predictors for operative success be identified?

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Detection of a large number of PE in PC samples in our Institution led to the development and implementation of preventive strategies. This study showed that the leprosy incidence would be reduced substantially by good BCG vaccine coverage and the combined strategies of contact tracing, early diagnosis, and treatment of infection and/or chemoprophylaxis among household contacts. In the LPS-stimulated RAW264.7 cells, CJT significantly decreased nitric oxide (NO) and interleukin (IL)-6 in a concentration-dependent manner by reducing inducible NO synthase (iNOS) and IL-6 mRNA levels. It is unclear to what degree a family history of gastric cancer is associated with stomach cancer risk in Korea. Primary cutaneous B-cell lymphoma successfully treated with highly active antiretroviral therapy alone: a case report and review of the literature.

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We investigated the temporal and regional profile of blood-brain barrier (BBB) permeability to both large and small molecules after moderate fluid percussion (FP) brain injury in rats and determined the effects of post-traumatic modest hypothermia (33 degrees C/4 h) on these vascular perturbations. The decrease was observed at postnatal days 14 and 21 and also in 90 day-old animals. No published data is available on the efficacy and side effects of this drug in Iranian patients.

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Increase in maternal plasma PTX3 in pregnancies that subsequently develop early PE is evident from 11-13 weeks but the underlying mechanism for such an increase remains uncertain. Low-carbohydrate high-protein (LCHP) diets are used commonly for weight reduction. These results suggest that activities of prairie dogs might further exacerbate the impacts of humans in fragmented urban rangeland habitats.

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Tumor-specific immunity in patients with prostatic adenocarcinoma or benign prostatic hyperplasia. Future empirical studies, by a qualitative method, may provide valuable information about the arguments underlying the ethical views of doctors on the limitations of different types of medical treatment. Meta-analysis of hemodynamic optimization in high-risk patients. The half-life of soluble lipase at 50 degrees C was calculated to be 4.5 h, while immobilized lipase did not lose any activity even after 8 h.

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A very high correlation was found between the activity of both enzymes in one neuron, although this correlation was certainly not linear. Influence of the polyelectrolyte poly(ethyleneimine) on the adsorption of surfactant mixtures of sodium dodecyl sulfate and monododecyl hexaethylene glycol at the air-solution interface. In settings with high amounts of unrecorded production and consumption, increasing the proportion of alcohol that is taxed could be a more effective pricing policy than a simple increase in tax.

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However, their overall low level of sequence conservation makes their characterization solely from sequence data difficult. Quantitative structure-activity relationships (QSARs) for the prediction of skin permeation of exogenous chemicals. Importantly, agrin isoforms greatly differ in their activities of inducing MuSK phosphorylation and of binding to alpha-dystroglycan. In females strong associations were seen between qat-use and the diagnosis of acute gastritis, and histories of jaundice, bronchitis and hepatic diseases. AOAA lesions were significantly attenuated by pretreatment with either 1,3-butanediol or coenzyme Q10, two compounds which are thought to improve energy metabolism.

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To document radical cystectomy (RC) outcomes in patients over 80 years old across Quebec during the years 2000-2009 and to examine potentially related factors. Reduced semen quality in chronic prostatitis patients that induce the release of apoptotic protein Omi/HtrA2 from spermatozoa. These results reveal that an HMG-domain protein can affect cellular responses to cisplatin and may be relevant to the clinical observation that cancer cells in specific tissues are particularly sensitive to cisplatin.

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Embryonic stem cells (ESC) were utilized as an important in-vitro model for the elucidation of the cardiac developmental processes since they can be easily manipulated by numerous signaling molecules, growth factors, small molecules and genetic manipulation. An extralobar sequestration receiving its blood supply from the left pulmonary artery, accompanied with pericardial agenesis, was noted at the time of operation.

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Double contrast arthrography of the knee in the diagnosis of meniscus injury (experience in Nairobi). Effect of wheat enzyme preparation on the performance characteristics of Tom turkeys fed wheat-based rations. This review describes a recently discovered family of aromatic prenyltransferases. We therefore measured intragastric bile acid concentration and its composition from individual bile acids, duodenogastric bile acid reflux rate, gastric emptying rate, and secretion rates of volume and acid in 30 patients with gastric ulcer and in 66 healthy controls, both in the fasting state and after feeding a liquid meal. Since Cogan first described COMA in 1952, many cases have been reported.

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This review will facilitate that re-evaluation through a brief review of AEDs used in the treatment of complex partial seizures, followed by a focused discussion on vigabatrin. The resolution of optical traps created by Light Induced Dielectrophoresis (LIDEP). Patients infected with hepatitis virus could encounter difficulties in obtaining dental care. immigrants waging seesaw battle over coverage for dialysis care in the West, Southwest. Therefore our findings suggest that the histaminergic system may modify the discriminative stimulus effects of cocaine and methamphetamine mediated through H1- and H3-receptors.

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We have concluded that parts of the brain with an important role for the survival have a strong expression of c-fos gene. The ethanol liquid diet groups did not show a decrease in body weight. If parvovirus B19 immunoglobulin G is present and immunoglobulin M is negative, the woman is immune and should be reassured that she will not develop infection and that the virus will not adversely affect her pregnancy. The stigmas of mental illnesses were assessed using the Perceived Devaluation-Discrimination Scale We directly compared the stigma level between North Korean defectors and the general population of South Korea. These libraries connect recombinant proteins to clones identified by DNA hybridization or sequencing, hence creating a direct link between gene catalogs and functional catalogs.

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We present a strategy to identify developmental/differentiation and plasma membrane marker genes of the most primitive human Mesenchymal Stem Cells (hMSCs). Adriamycin/NaCl treated hearts produced reduced cardiac output and left ventricular systolic pressure compared to controls (NaCl/CaCl, group III) or to adriamycin/carnitine treated hearts (Fig. Both dissociated and associated heterophoria have been used as indications for prismatic correction. Using an equilibrium dialysis technique, moles (Gamma(2)(1)) of cationic and anionic surfactants bound per kilogram of proteins of various types in aqueous media have been measured previously in this laboratory under different physicochemical conditions. Familial right ventricular dilated cardiomyopathy associated with supraventricular arrhythmias.

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Patients with muscular VSD can currently be treated with the hybrid approach. Biomimetic synthesis of copolymer-silica nanoparticles with tunable compositions and surface property. On the site by which alpha-dendrotoxin binds to voltage-dependent potassium channels: site-directed mutagenesis reveals that the lysine triplet 28-30 is not essential for binding. Neuropsychiatric adverse effects of centrally acting antiobesity drugs.

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This review discusses recent neuroimaging studies reporting on impairment in brain functioning relevant to language processing in individuals with schizophrenia and those who are at a genetic risk for its development. The acquisition time of infection: a determinant of the severity of hepatitis C virus-related liver disease in renal transplant patients.

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Cobalt concentrations below 10 microg/mL or 0.17 mmollmL in the cell culture medium had no significant effect on human osteoblast proliferation and function. Primary sarcomas of the aorta, pulmonary artery, superior vena cava, inferior vena cava, and the heart are rare neoplasms. Antidepressant prescribing increased exponentially over the period examined, whilst admissions for depression markedly decreased. Tumoral levels of TGFalpha, EGFR and PDGF-A/B are not predictive of radioresponsiveness in oropharyngeal cancers. In contrast to wild-type cells, Apaf1-deficient neurons exhibit delayed DNA fragmentation and only peripheral chromatin condensation.

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The SSc is innervated by two or more discrete motor nerves and previous studies have indicated some difference in electromyographic (EMG) activity between the upper and lower portions of the muscle. Heliotrope-like eruption mimicking dermatomyositis in a patient treated with imatinib mesylate for chronic myeloid leukemia.

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Metabolism in vitro of testosterone (T) to 17 beta-hydroxy-5 alpha-androstane-3-one (DHT) and 5 alpha-androstane-3 alpha,17 beta-diol (3 alpha) by the 800 g supernatant fraction of ileum from rats. Mean survival time after the operation was 5.6 months for patients treated by drainage. Intratumoral injections of plasmid DNAs encoding highly active forms of either CD40 ligand or GITR ligand had no significant antitumor effects in this model, although improved DNA delivery techniques could possibly improve this strategy. Serious complications can include congestive heart failure, myocardial infarction, and thromboembolism. IFI27 is highly expressed in psoriatic lesions but its function has not been known.

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We have considered the electroconvective flow induced by concentration polarization near an ion selective surface as a model problem representing chaotic elecrokinetic phenomena. We further increase the quality of elemental images by a digital restauration. However, an independent validation of the accuracy of this information is mandatory.

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THE USE OF COMPENSATION FILTERS FOR IMPROVING THE DOSAGE DISTRIBUTION IN TELECOBALT THERAPY OF CERVICAL CARCINOMA felis-infected mice on a uniform C57BL/6 background housed in specific-pathogen-free conditions. Validating ROS1 rearrangements as a therapeutic target in non-small-cell lung cancer. Conjugative transfer of the erm(A) gene from erythromycin-resistant Streptococcus pyogenes to macrolide-susceptible S. Due to use of the technique valuable information on individual response was obtained.

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Selective magnesium sulfate prophylaxis results in an increased overall incidence of eclampsia because of more seizures in women with nonsevere gestational hypertension who are not given magnesium sulfate prophylaxis. It is important to understand various factors that influence and encourage young teenagers to start smoking or to use other tobacco products.

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The evaluation was conducted through various scales at t0 (beginning) and t1 (end of the training). Well designed prospective clinical trials are awaited to define the exact role of these imaging studies in the diagnosis and guidance of therapy. mRNA expression of alpha upsilon integrin, syndecan-1 and glypican-1 was significantly higher in primary fibroblasts than CAR. Radial nerve potential was studied at the level of the wrist in 13 normal subjects. Alpha-synuclein belongs to a family of structurally related proteins expressed highly in the brain and is the major component of filamentous deposits present in a range of neurodegenerative diseases (synucleinopathies).

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De novo exon duplication in a new allele of mouse Glra1 (spasmodic). These data support the notion of behaviorally significant functional regeneration of olfactory neurons. The physiological implications of this interaction are discussed.

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Churg-Strauss syndrome--recent developments in diagnosis and treatment To compare the antibody concentrations against Bordetella antigens in health care workers in a pediatric hospital with those of two different populations without professional contact with children. Effect of progabide on serum phenytoin and carbamazepine concentrations.

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Serum fibrinogen level more than 4.00g/L was defined as hyperfibrinogenemia. Univariate and multivariate analyses were performed using the World Health Organisation (WHO) toxicity score and grouping together toxicity scores in different bimodal and trimodal groups. The intracellular uptake exhibited a remarkable improvement of the internalization, when the NPs were conjugated to the CPPs. Two different mutations at Gly-90 in the second transmembrane helix of the photoreceptor protein rhodopsin have been proposed to lead to drug study about metronidazole tablets different phenotypes. Thus, the growth rate was most likely restricted by the capacity to absorb and utilize yolk.

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Cutaneous leishmaniasis (CL) has been an endemic disease in Aleppo, Syria for many decades. The effect of finite acceptance angles for both ionic fragments and photoelectrons has been included in the calculations, as well as the effect of rotational averaging around the fragmentation axis. Standard ribavirin prescribing information sandoz criteria for discharge were used for all study patients. AUTORADIOGRAPHIC STUDIES ON 3H-LEUCINE UPTAKE BY ADENOHYPOPHYSIAL CELLS IN VITRO. Passage of mannitol into the brain around gliomas: a potential cause of rebound phenomenon.

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The persistent, slowly inactivating fraction of the sodium current is involved in key functions in the CNS such as dendritic integration of synaptic inputs and cellular excitability. Asymptomatic Enterocytozoon bieneusi microsporidiosis in captive mammals. Our study illustrates the possibility of screening compound libraries in both iron-rich and iron-limiting conditions to identify antimicrobials that may selectively target iron scarcity-adapted bacteria and highlights the usefulness of building combinatorial libraries of compounds having scaffolds with structural similarities to siderophores to feed into antimicrobial screening programs. In mitogen-activated and non-activated lymphocytes from C57BL and C3H mice (AHH responsive strains) the percentage of blastogenesis induced by BA or MCA was higher than in lymphocytes from the non-responsive strain (DBA/2). Substance P reduced the variability of subthreshold locomotor-related depolarizations and spiking in aceclofenac gel vs diclofenac gel generic motor neurons during network activity.

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The side effects and potency of nitroglycerine depend on mitochondrial aldehyde dehydrogenase (ALDH-2). Molecular and genetic observations provide a framework for the formulation of hypotheses concerning the mechanisms by which the Delta rotec industries shropshire uk ligand and Notch receptor interact and the Delta-Notch signal is transduced in a manner that can affect the adoption of distinct fates by different cells.

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By enabling profiling of active and TIMP-bound MMPs, our novel method may open coxicam medicine cabinets opportunities for the screening of early predictors for BOS. These findings provide evidence that breeders in a genetically monogamous species may avoid the fitness costs of reproducing with a genetically similar mate. Detrended fluctuation analysis of the magnetic and electric field variations that precede rupture. An agenda for research on the sustainability of public health programs. Without Syrian hamster embryo cells, 1,3-dinitropyrene had weak mutagenic activity and 1,8-dinitropyrene had strong, dose-related mutagenic activity.

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Direct synthesis of nanocrystalline silver from the reaction between silver r180 pill tizanidine carboxylates and n-trioctylphosphine. Combinatorial labeling of single cells for gene expression cytometry.

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Purification of a NifEN protein complex that contains bound molybdenum and a FeMo-Co precursor from an Azotobacter deflamat 2 gel schwangerschaftskalender vinelandii DeltanifHDK strain. Characterization of the truncated hemoglobin THB1 from protein extracts of Chlamydomonas reinhardtii. Family history has no relationship with anxiety and depression among FD patients. We obtained an increase in resolution of the anisotropy decays by using multiple excitation wavelengths, chosen to provide a range of fundamental anisotropy values. The toxin caused the swelling and disruption of HL-60 cells and formed a functional pore in the lipid raft microdomains of sensitive cells.

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A simple and cost-effective first-tier screening strategy for VIP-derived activities in B. Patient education facilitates the maintenance and promotion of modafinil effects on gabapentin self-care behaviors. Clinical evaluation of 20 patients at a mean of 14.9 years after transfixation of the epiphysis revealed some evidence for the presence of FAI in affected hip joints. The strips can measure many parameters and have the advantage of being able to rapidly provide results at a low cost.

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Preparative isolation and purification of antioxidative stilbene oligomers from Vitis chunganeniss using high-speed counter-current chromatography in stepwise elution eleotris tecta drug mode. Numerous tools have been developed to analyze Illumina genotype microarray data for copy number variant (CNV) discovery, although commonly utilized algorithms freely available to the public employ approaches based upon the use of hidden Markov models (HMMs). Findings from this study present a strong case for use of angled drill guides. The purpose of this study is to define landmarks to locate the PIN intraoperatively in order to avoid neurological complications.

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West Nile virus outbreak in horses, southern France, 2000: results of a serosurvey. Systemic sarcoidosis with necrobiosis lipoidica-like scalp lesions. After levofloxacin 500 mg sinus infection administration of rAAV-shRNA, there was a significant reduction of AMCase expression in the lung and in bronchoalveolar lavage fluid (BALF) cells of sensitized mice. The mechanism of radiosensitization is due to inhibition of repair from sublethal damage and potentially lethal damage. It may present with obturator neuralgia, as a palpable mass or, in cases of bowel necrosis, as ecchymosis of the thigh.