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Crosslinking of histones in mouse liver nuclei and extended chromatin with a bifunctional reagent leads to the formation of H1-H1o heterodimers as well as H1o-H1o homodimers. Complete genome sequences are now available for three members of the Mycobacterium tuberculosis complex and the related intracellular pathogen M. Influx of neutrophils was quantified by myeloperoxidase-enzyme-linked immunosorbent assay. Monocyte incubation at hypothermic temperatures (34 degrees C) reduced HLA-DR surface expression, delayed TNF-alpha clearance, and increased IL-10 release. The presented results demonstrate that efficient nuclear transport of pp65 is mediated by one dominant NLS and additional targeting sequences.

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The three chief problems arising when an expert opinion is to be given are dealt with in brief, and the forensic significance of the depressive syndrome is described, without entering into the question of giving an opinion as to responsibility. Quantitative analysis of illusory movement: spatial filtering and line localization in the human visual system.

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We also observe a nonlinear evolution of the jump in isobaric heat capacity at the glass transition when substituting SiO(2) for B(2)O(3), which can be accurately predicted using a combined topological and thermodynamic modeling approach. If urodynamic investigations were to be valuable in the diagnostic work-up, patients with normal and abnormal findings would have different treatment results.

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Persistence of Escherichia coli O157:H7 in barley silage: effect of a bacterial inoculant. The growth of bicrystalline ZnO nanocombs can be explained by polar-surface dominated growth and twins induced growth mechanisms.

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Pigmentation of skin graft is improved by cryopreservation of human skin with trehalose. Stimulation of adipose tissue fatty acid synthesis and glucose utilization evoked by feeding in control rats was greatly enhanced by prior food restriction. These results are discussed in relation to recent basic research addressing the influence of effort on stimulus value.

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Traumatic lesions of adrenal glands in paediatrics: about three cases. In vitro, PPAR-gamma agonist 15-deoxy-Delta(12,14)-prostagladlin J(2) (15d-PGJ2) decreased cell-scraping-induced superoxide generation through suppression of NADPH oxidase activity via down-regulation of p22(phox) and gp91(phox). The stress-disequilibrium theory: chronic disease development, low social control, and physiological de-regulation. Mammalian circadian rhythms are generated by a feedback loop in which BMAL1 and CLOCK, players of the positive limb, activate transcription of the cryptochrome and period genes, components of the negative limb. Admission evaluation including excretory urography, retrograde pyelography, computed tomography and cystoscopy revealed multiple urothelial tumors in the left renal pelvis, ureter and bladder.

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Relation of black race between high density lipoprotein cholesterol content, high density lipoprotein particles and coronary events (from the Dallas Heart Study). Sustained hypermetabolic sepsis in rats: characterization of the model. Retrolental fibroplasia: new thoughts on pathogenesis and prevention.

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Additionally, the diagnostic value of the electrocochleography (EcochG) was determined. Aldosterone on sodium transport of rat distal colon in long-term adrenalectomy during acute and chronic substitution. Impact of intermittent preventive treatment in pregnancy with azithromycin-containing regimens on maternal nasopharyngeal carriage and antibiotic sensitivity of Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus: a cross-sectional survey at delivery.

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Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions. Survival of isolated Rsk2 deficient motoneurons is not reduced, but these cells grow significantly longer neurites. Fulminant Capnocytophaga canimorsus (DF2) septicaemia and diffuse intravascular coagulation in hairy cell leukaemia with splenectomy.

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THE EFFECTS OF INHIBITORS OF RNA AND PROTEIN SYNTHESIS ON CYTOLOGICAL DEVELOPMENT DURING MEIOSIS. Important questions remain in our understanding of BSRC with respect to its pathogenesis, epidemiology, optimal treatment, and prognosis, including the determinants of remission and relapse, as well as the best strategy for monitoring disease activity, progression and response to therapy with electroretinographic and psychophysical testing, established and emerging imaging modalities, and peripheral cytokines profiles. The effects of short-chain fatty acids on HNSCC cells was examined using tissue culture and immunoblotting techniques. A phase I clinical trial of this therapy was started in mid 2010 and is currently underway.

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Preoperative sarcopenia was defined as the presence of a normalized TPA in the lowest sex-specific tertile. Results demonstrated developmental change in the motor cortices and Middle Temporal Gyrus. The ready availability of comparative peer quality control values helps to improve analyzer precision and accuracy, and simplifies instrument validation and calibration. PMN elastase and neopterin increased during storage of whole blood and RBC.

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Breast cancer cell-derived cytokines, macrophages and cell adhesion: implications for metastasis. Regression analysis of box office receipts as a function of film rating, production budget, year of release and presence of smoking for 1232 films released in the USA between 2002 and 2010. Positive selection of a Qa-1-restricted T cell receptor with specificity for insulin.

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To review new developments in second-line treatment for transitional cell carcinoma of the urinary bladder focusing on advances and findings within the last year. Effect of adjuvant endocrine and adjuvant chemoendocrine therapies on metastasis of androgen-dependent Shionogi carcinoma 115. Combined antagonism of adrenoceptors and dopamine and 5-HT receptors underlies the atypical profile of clozapine.

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The bio-social dimensions of poverty, Tata Memorial Hospital, Bombay, 18 March 1994. Records were gathered from the National Poison Control and Management Center (NPCMC), the Philippine General Hospital, De La Salle Medical Center, and other hospitals, and reviewed research studies conducted in the Philippines. One widely cited model of insulin signalling leading to glucose transport is that of Sedaghat et al. Members of the ABCA subfamily of ABC transporters and other ABC proteins such as ABCB4, ABCG1 and ABCG5/8 implicated in lipid transport play important roles in diverse biological processes such as cell signalling, membrane lipid asymmetry, removal of potentially toxic compounds and metabolites, and apoptosis. A clinical process-outcome-study of concentrative movement therapy

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Its killer phenotype was incurable, and extrachromosomal genetic elements were not detected. Sensitisation to halothane-altered liver components in severe hepatic necrosis after halothane anaesthesia. We concluded that these resins have potential for human and veterinary medicine. DEXAMETHASONE AEROSOL IN THE SYMPTOMATIC TREATMENT OF CHRONIC BRONCHIAL ASTHMA IN CHILDREN

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The protein kinase C inhibitors, sphinganine and 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7), attenuated the induction of differentiation markers by etoposide. o-Iminobenzosemiquinonato(1-) and o-amidophenolato(2-) complexes of palladium(II) and platinum(II): a combined experimental and density functional theoretical study. Serum follicle-stimulating hormone (FSH) level was used as a surrogate marker for ovarian function. Phototropin 1 (phot1) is a Ser/Thr photoreceptor kinase that binds two molecules of flavin mononucleotide as its chromophores and undergoes autophosphorylation in response to blue light.

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The purpose of these directives is to assist health care professionals in the practice of clinical densitometry. It is suggested the perspectives of using oligosaccharide probes, which are the ligands for endogenous receptors-lectins in tumour diagnostic and guiding transport of medicinal products. Gemcitabine, used in the treatment of pulmonary, pancreatic and urothelial carcinomas, is generally well tolerated, but has recently been implied in the occurrence of TMA.

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Taxonomy of Clostridium bifermentans and Clostridium sordellii, III. Therefore, immunoregulation caused by intravenous fat emulsions with different n-3 to n-6 fatty acid ratios was studied in an in vivo model. Prognostic implications of microscopic proximal bronchial extension in non-small cell lung cancer. In this work, a selection of the best features for multivariate forensic glass classification using Scanning Electron Microscopy coupled with an Energy Dispersive X-ray spectrometer (SEM-EDX) has been performed. However, the empty active site of human procarboxypeptidase B has two alternate conformations in one of the zinc-binding residues, which account for subtle differences in some of the key residues for substrate binding.

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The results showed that there was a higher MDA level in the transplant group than in the control group one week after the transplant. The Se and Hg in biological samples were measured by electrothermal atomic absorption spectrometry and cold vapor atomic absorption spectrometry, prior to microwave acid digestion, respectively. However, the value of WBV in a training program remains unknown. The electronic structure, absorption spectra, and thermodynamic properties of crystalline styphnic acid and its metal salts (potassium, barium, and lead styphnates) have been studied using density functional theory within the local density approximation. It is postulated that in chick some degree of oligodendrocytic cell death occurs normally during myelination.

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This technique also permitted the visualization of the ascending dorsal and ventral noradrenergic bundles as well as varicose fibers and terminals in a pattern identical to that reported with histofluorescence, autoradiographic, biochemical and classical immunofluorescence techniques for the identification of noradrenergic fiber distributions. The first major step for this program was to train methodologists to manage working groups that compose the guidelines, and to create a reference document that describes the development of the program. Here, an ANP method based on the diamond hydride stationary phase is presented for profiling biological small molecules by LC. These changes show that the extent of Ca influx regulates the smooth-muscle contraction of the nasal blood vessels consistent with the reports concerning other vascular smooth muscle. CD44 was expressed in 23/27 BPCs, 6/8 MPCs, 7/30 adrenocortical adenomas, and 4/22 adrenocortical carcinomas.

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The distribution of gestations at delivery suggested that in twin pregnancies low AFP values gave an early warning of growth retardation while high values signal possible premature delivery. The lobe difference in this respect corresponds to a concomitant difference in morphology and tissue chemical content.

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Letter to the editor: complications in neurosurgery: the need for a common language. The increase of serum sCD40L expression is possibly involved in the occurrence and development of SIVD. A history of having eaten insufficiently cooked meat is thus extremely important for correct diagnosis. Acceptable reasons for repair of femoral artery pseudoaneurysms are persisting or enlarging femoral artery pseudoaneurysms, associated pain or neuropathy, and rupture of femoral artery pseudoaneurysms.

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acidophilus SFMD-1 and commercial inactivated FMDV vaccine rose rapidly to 0.84 and 0.70, respectively, by day 42, then sustained a high level by day 49. Cross-sectional analysis showed significant differences related to level of functioning but not to age or etiology of disability.

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Tremolite also contaminates talc, the most common non-asbestos mineral fiber in our control cases. Hence, in order to maintain compatibility of the results, the use of this particular spectral TD procedure should be advocated in clinical praxis. The anabolic effect of insulin in hepatocytes was strictly dependent on the permissive action of leucine. Funduscopic examination showed annual choroidal detachments and geographic retinochoroidal atrophy in the posterior pole OU, and serous retinal detachment OD.

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Bases for the description of monochromatic, strongly focused, scalar fields. The purpose of this work was the qualitative characterization of a recently transesterification product obtained from the coconut oil in the presence of polyglycerol-6 to produce a new PEG-free secondary surfactant.

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There were indications for the myomectomy during pregnancy in the group of 26 women, in next 55 women leiomyomas were diagnosed in the course of pregnancy but myomectomy was performed during caesarean section. The present study evaluated whether deprivation (24 h)-induced food intake was altered following systemic administration of either the D1 agonist, SKF-38393, the D1 antagonist, SCH-23390, the D2 agonist, quinpirole, or the D2 antagonist, haloperidol, alone or in combination with the general opioid antagonist, naltrexone. coli strain DH5 alpha were determined using proton nuclear magnetic resonance spectroscopy. Secondary lymph organs, such as submaxillary lymph nodes and spleen, have been shown to exhibit a 24 h variation in blastogenic proliferative capacity and distribution of B and T subsets, with specific achrophases depending on the parameter studied or the lymphoid organ considered.

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To do so, we used neurophysiological recordings to estimate the vibration and pressure sensitivity of African lungfish (Protopterus annectens) in both water and air. History and physical findings, pulmonary function tests, arterial blood gases, distance achieved in a 12-min walk, dyspnea score, electrocardiogram, chest radiograph, and radionuclide multigated ventriculography. Beta-adrenergic pathways played little role in causing these reflex responses. Fast cyclic voltammetry has been used to study the relative importance of neuronal dopamine (DA) uptake and D2 autoreceptor stimulation on the control of the extracellular concentration of electrically evoked DA in rat brain slices containing aCPu and NAc.

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Progress in the filed of pulmonary medicine in the last 100 years: Medical history of interstitial pneumonia In this report, the role of hsp72 in the process of aggregation and disaggregation was investigated using: non-tolerant rat-1 cells, thermotolerant rat-1 cells (rat-1 TT), and transfected rat-1 cells constitutively expressing the human inducible hsp72 gene (HR-24 cells). Very low-intensity anticoagulant therapy in elderly cardioembolic stroke patients with nonvalvular atrial fibrillation

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A dose-effect relationship between duration of balance training and injury incidence is evident. Furthermore, increased cell death and enhanced extracellular trap formation observed in SLE-derived neutrophils might have key roles in the induction of autoimmunity and the development of organ damage in patients with SLE.

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However, this method often fails to converge to the appropriate minima without good initial parameter estimates when multi-exponential models are involved, making automated analysis of complete multislice or volume data sets problematic. This was deduced from the fact that platelet eluates devoid of anti B-cell antibodies effectively inhibited in MLC.

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We are the stories we tell: narrative knowing in nursing practice. Sequencing, as well as quantitative PCR of small RNAs, uncovered 10 miRNAs enriched in planarian stem cells. Of seven retinular axons, four occur peripherally and the remaining three occur centrally in the neuropil.

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Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2. Fundus examination revealed severe sheathing of all retinal vessels with neurosensory retinal detachment suggestive of frosted branch angiitis. As the patient remained icteric for a month thereafter the gallbladder with stones was removed. Increased phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor subunit GluR1 (p-Ser831) was seen in DOM-potentiated slices.

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Differential sensitivity to regional-scale drought in six central US grasslands. By representing the locomotor movement as a discrete-time return map and using the implicit function theorem we show that the number of recovery steps needed following a perturbation depends upon the goals of the control mechanism. Safeguarding the health of the Soviet people (figures and facts) These data support the need for nutrition education in Arkansans with less than a high school education. Acid secretion in normal stomachs was significantly reduced by nitroprusside and PGE2 but was not affected by either L-NAME or indomethacin.(ABSTRACT TRUNCATED AT 250 WORDS)

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Among renewable energy resources, solar energy is by far the largest exploitable resource, providing more energy in 1 hour to the earth than all of the energy consumed by humans in an entire year. It was found that the beneficial effects of double-stranded polynucleotides cannot be mimicked by polyadenylic acid only, despite its anti-senescence effect, namely, it accelerates the apparent protein turnover, cf., biological half-life.

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The structures of the isolates were determined with the help of spectroscopic data including 2-dimensional NMR as well as comparison with reported data. Subjects underwent standard imaging to exclude metastatic disease before PET. Other work indicates that gamma-tubulin-mediated microtubule nucleation, although necessary, is not sufficient for mitotic spindle assembly but requires additional proteins that regulate microtubule nucleation independently of centrosomes. The bulk of ATP is associated to proteins in the living cell: a release kinetics study. ROLE RELATIONS, SOCIOCULTURAL ENVIRONMENTS, AND AUTOCRATIC FAMILY IDEOLOGY.

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Mouse genital ridges in organ culture: the effects of temperature on maturation and experimental induction of teratocarcinogenesis. In patient with relatively small traumatic cartilage defect, microfracture technique, autologous osteochondral graft transplantation, or autologous cultured chondrocytes transplantation are performed. The purpose of this study was to evaluate the diagnostic performance of CT in determining whether a small solid renal enhancing mass is benign or malignant. Unloading induced a generalised enhancement of NWR excitability without modifying the reflex receptive field organisation.