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Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives. CSF analysis revealed elevated protein level with normal cell count. Controlled trial of prophylactic treatment in childhood urinary-tract infection.

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There is strong evidence to support that the use of MBSR can improve a range of biological and psychological outcomes in a variety of medical illnesses, including acute and chronic pain, hypertension, and disease prevention. Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A. Shock wave treatment of salivary duct stones: substantial progress with a minilithotripter.

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A novel type of metastable complexes of metal (such as Na) atoms with a super-fluorinated carbon molecule is investigated, with a carbon atom exhibiting a unique, pentavalent character. RESEARCH ON THE TIME RELATIONS BETWEEN DISCHARGES FROM MOTOR NEURONS OF MUSCLE-ANTAGONISTS IN MAN (BY CROSS-CORRELATION ANALYSIS) The difference in exposure corresponded to a relative risk of about 7.0, and a clear dose-response relationship could be demonstrated. Specimens were collected from the external canals of subjects with clinically diagnosed acute otitis externa. Preoperative laboratory date revealed a normal platelet count and normal coagulation profile.

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Exposure times were recorded for 316 patients undergoing spinal interventional procedures before and after the implementation of this project. Finally, in vivo plasma concentrations of alpha-mangostin, the most abundant xanthone derivative found in mangosteen, were predicted using Simcyp and found to be well above their respective in vitro K(i) values for CYP2C8 and CYP2C9. 3 patients were studied, 1 with polycythaemia vera and 2 with myelofibrosis, which was preceded by polycythaemia vera in 1 of the cases.

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Four weeks after the intervention, repeat laparoscopy was performed in all horses. Beneficial effect of glatiramer acetate (Copaxone) on immune modulation of experimental hepatic fibrosis.

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Tumor uptake of FDG was detected in 17 of 21 patients with malignant disease. Radioactive DAT from each specimen was assayed by gamma-counter. Ten patients were scanned for myocardial perfusion on 3T or 1.5T scanners, and short- and long-axis slices were acquired. DNA synthesis (LI) and mitotic activity (MI) were studied at different times of the day in the developing mammary gland end bud of the postnatal mouse.

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Properties, stage-dependent expression and localization of Plasmodium falciparum M1 family zinc-aminopeptidase. The two universal primers were able to amplify full size 16S rDNA from all of the 20 bacterial species tested. Photoageing is the superimposition of photodamage on the ageing process. In all 7 cases of purulent meningitis, the simultaneous administration of antibiotics and immunoglobulins was effective. The increased histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE.

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Decreased serum and pineal concentrations of melatonin and N-acetylserotonin in aged male hamsters. To find out whether the mechanisms described for Kif1A and CeUnc104 cover the full spectrum of Kinesin-3 motors, we characterize here NcKin3, a novel member of the Kinesin-3 family that localizes to mitochondria of ascomycetes. The peroxisome proliferator-activated receptor gamma (PPARgamma) ligands 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms. We examined the sensitivities of proliferation and progress through the cell cycle to each of nine potassium channel antagonists. Taken altogether these data stress the biological activity of SCF as a cytokine which is able to maintain MMC in a well differentiated status, and suggest a more in depth evaluation of possible effects of SCF on melanoma cells.

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Identification and simultaneous quantification of five alkaloids in Piper longum L. Site-selective artificial ribonucleases: oligonucleotide conjugates containing multiple imidazole residues in the catalytic domain. This article also includes a discussion of normal airflow for speech and the perceptual speech characteristics that often occur when there is abnormal nasal airflow. The method is used to calculate the free-energy difference between two conformational states of the alanine dipeptide in vacuo, and of the beta-hairpin from protein G with an implicit solvation model. Surgical and topical modalities have been invented and substances were applied topically to alter the ageing process.

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Surface-induced phenomena in uncompensated collinear antiferromagnets. In this study, well-controlled laboratory experiments were performed to elucidate seawater RO membrane fouling by alginic acid. Estimated weekly time-weighted average exposures for pathologists, residents and technicians were determined to be between 0.61 and 1.32 parts per million with little difference between work roles. As part of an effort to further elucidate the mechanism whereby fluorinated ether anesthetics express their various toxic effects, Golden Syrian hamsters were utilized to determine acute and subchronic toxicities of the anesthetic metabolite 2,2,2-trifluoroethanol (TFE). The wave size, type of seafloor, and number of surfing heats were also recorded for each day.

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Rheumatoid factor: its nature, specificity, and production in rheumatoid arthritis. Mesenteric vasculitis as the initial presentation in children with systemic lupus erythematosus. Under optimum experimental conditions, the hydroxylated product of ninhydrin had excitation and emission maxima at 300 and 406 nm, respectively. Coping strategies may have an important role in developing overweight/obesity, particularly in men.

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The expression of candidate genes was confirmed at RNA level by quantitative RT-PCR and at the protein level by Western blots and immunocytochemistry. Few mycorrhizal species were found to have GH32 genes as compared to other guilds of plant-associated fungi, such as pathogens, endophytes and lichen-forming fungi. Small doses of Fostrolin, however, caused a drop in T and PRL levels.

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Firmicutes and Actinobacteria were the major bacterial groups in both the rhizosphere and bulk soil at all 4 growth stages of S. In addition, its use in other clinical settings is being actively explored. The predominance of medium-sized spinal ganglion cells may indicate that the stomach is innervated mainly by small myelinated rather than unmyelinated splanchnic afferent fibers.

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We have previously shown that p107, a member of the retinoblastoma (Rb) cell cycle regulatory family, has a unique function in regulating the pool of neural precursor cells. The difference in size between the two molecules shows that cleavage occurs at the N-terminal side of glycine-681, demonstrating that the organic radical is indeed located on this amino acid residue.

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Temperature sensitivity of axonal transport in hibernating and nonhibernating rodents. In this paper, we investigate the ultimate bound and positively invariant set for a class of Hopfield neural networks (HNNs) based on the Lyapunov stability criterion and Lagrange multiplier method. We report a 5-year-old girl with a complex neurological syndrome and severe hypomyelination on brain magnetic resonance imaging. Visual evoked potentials were recorded in eight children during hypothermia and circulatory arrest. Hematologic and serum biochemical changes in Salmonella ser Typhimurium-infected calves.

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It is concluded that the condition differs from the syndrome of inappropriate secretion of antidiuretic hormone (SIADH): the increase in plasma IR-AVP concentration may be associated with dehydration due to vincristine toxicity. Recent technological advances in small molecule synthesis and high-throughput screening have made such mechanism-directed small molecule approaches a powerful and accessible experimental option. The mutated PC did not appear to alter these responses in our model of HS and resuscitation. An understanding of the radiologic findings for variant types of HCC can be helpful in the differential diagnosis of hepatic tumors.

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Oxidation was also induced by treatment of unoxidized SLPC with ultraviolet irradiation. Computed tomography grading schemes used to predict cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a historical review. VEPs recorded from striate cortex were basically consistent between animals (especially at low light intensity), remained remarkably stable over time, and compared favorably to VEPs reported by other investigators. To improve the wetting of the gap and sample confinement, the edges of the tips forming the gap were hydrophilized by means of silicon dioxide deposition.

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Functional anatomy of pentylenetetrazol and electroshock seizures in the rat brainstem. Here, we explored combined beta-glucan with bevacizumab therapy for human lung cancer using murine xenograft models. Treatment effects varied as a function of risk, and more so with variables capturing relational risk factors than individual risk factors.

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Telemedicine, the use of telecommunication technologies to provide health services over some distance, has a history that spans more than five decades. The preoperative diagnosis of PAES was made by duplex ultrasonography, three-dimensional computed tomography angiography, magnetic resonance imaging, or conventional angiography. Hormone manipulation experiments with Japanese quail (Coturnix japonica) and zebra finches (Taeniopygia guttata) reveal dissociations between different components of sexual and social behavior.

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The objective of this research was to investigate the presence of sodium-dependent multivitamin transporter (SMVT) on rabbit corneal epithelial cells. It is well known that MVOCs can modulate the physiology of plants and microorganisms and in this Opinion we propose that MVOCs can be exploited as an ecofriendly, cost-effective, and sustainable strategy for agricultural practices. Immunohistochemical techniques were employed to investigate the distribution of orexin-A-like immunoreactivity in the Japanese seaperch (Lateolabrax japonicus) pituitary.

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A dose dependent increase of wild type recombinants was found for DMN concentrations ranging from 68 microM to 680 microM. Comparison of contact lens multipurpose solutions by in vitro sodium fluorescein permeability assay. The aim of this study is to determine the histopathological changes of rat larynx mucosa with exposure to chronic thinner inhalation. Recently, a transmastoid approach has been described as another surgical option in cases of SSCD, an alternative that could avoid the known risks of a middle fossa craniotomy. To explore the relatively efficacious acupuncture treatment for chloasma, to promote its clinical application in medical settings.

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Several pre-adult life history traits (development time, survival and competitive ability), adult life history related traits (wing size, wing shape and wing-aspect ratio), and wing size and shape asymmetries were measured at the three temperatures. The different distributions of insertions/deletions and SNPs are clearly related to the two different responsible mechanisms, namely recombination and point mutations.

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We performed a comparison of the performance of six methods applied to the prediction of two human MHC class I molecules, including binding matrices and motifs, ANNs, and HMMs. The types of inhibition of thrombin by NTI-1 and NTI-2 were non-competitive and competitive with inhibition constants (Ki) values of 11.7 microM and 211 nM respectively. HBO makes it possible to reduce the doses of glucocorticoids and the period of treatment and hospitalization of patients. Salt and geographical mortality of gastric cancer and stroke in Japan.

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Considering the limitations of the empirical bases here analyzed, one questions the implied assumptions in the meanings of autonomy sustained both in the public and in the private components, departing from hypotheses on the delineation of independent tendencies toward the expansion of universal coverage and he restratification of supply and demand. The risk of disease transmission in nursing and treatment of patients with positive HIV antibodies and patients with AIDS We demonstrate by numerical simulation that the general features of the loss spectrum of photonic crystal fibres (PCF) with a kagome structure can be explained by simple models consisting of thin concentric hexagons or rings of glass in air. 1965.-The uptake of specific C(14)-deoxynucleosides by a type III encapsulated (virulent) strain of pneumococcus in resting-cell suspensions is enhanced when such deoxynucleosides are added as part of a supplement consisting of other deoxynucleosides, deoxynucleotides, an oligo(deoxy)nucleotide fraction derived from a deoxyribonuclease-treated calf-thymus deoxyribonucleic acid, and orthophosphate. Solid pseudopapillary tumor of the pancreas (SPTP) is a rare primary pancreatic neoplasm of unknown etiology, occurring most commonly in young women.

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The high burden of long working hours is a main reason for this. The discontinuation of tricyclic antidepressants (TCAs) can produce symptoms suggesting cholinergic overdrive. Nerve growth factor influences the distribution of sympathetic sprouting into the hippocampal formation by implanted superior cervical ganglia.

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The expression of viral proteins by adipocytes was confirmed using a fusion test. Recent studies have shown that the serine protease thrombin, depending on its concentration, plays an important role in neuronal degeneration or protection after cerebral ischemia. A study of the Bernard-Soulier syndrome in two unrelated families using different polyclonal antibodies in a sensitive immunoblot assay showed residual amounts of platelet membrane glycoprotein (GP) lb in the eight homozygotes, as well as the near-absence of GPlb beta and GPIX. Autopsy and placental examination are the most useful investigations in assisting formal classification of cause of death. Rats were collected from various areas in Guangxi in combination with plague surveillance and rat lung specimens were examined by ELISA for hantavirus antigen, and M segment of positive specimen was partially amplified with RT-PCR and sequenced.

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Hyperhomocysteinemia is independently associated with albuminuria in the population-based CoLaus study. We briefly review important advances in molecular microbiology, and then discuss specific assays that have been implemented in clinical microbiology laboratories throughout the country. The results of both procedures show that sialic acid is located exclusively in the head plasma membrane and in the acrosomal membranes. In two anesthetized guinea pigs already implanted with thermocouples, ventral and post-auricular surgery to expose the middle ear had no effect on the CAP, when low-speed drilling was used to open the auditory bulla. These results attest to the adequacy of these proteins extraction methods for proteomic studies.

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First-milking colostrum was collected from two cows and blended with fresh whole milk in immunoglobulin concentrations ranging from 7.5 to 123.8 mg/ml for immunoglobulin G, .38 to 5.53 mg/ml for immunoglobulin A, and .46 to 11.19 mg/ml for immunoglobulin M. Two types of repair are discussed: (1) a nonspecific repair (characteristic of both haploid and diploid cells), and (2) a diploid-specific repair (characteristic of diploid cells only). In the maternal plasma the activity is relatively constant within the standard range of non-pregnant women. Their tumors were located in the vermis and fourth ventricle in 8 patients, in the cerebellar hemisphere in 1, fourth ventricle in 1, and 1 patient had a fourth ventricular tumor extending the cerebello-pontine angle. The evaluation of the final draft of the RD toolkit confirmed that it reflected the visions of PHC.

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The extracellular-signal regulated kinase (ERK)/mitogen-activated protein kinase kinase (MEK) cascade plays a pivotal role in many of the essential cellular processes underlying embryonic development, including responses to major developmental changes. Extractable collagen, as measured by hydroxyproline, increases during this time by a factor greater than 1.5 times the reference control values of normal lung. Gastric mucosal histamine in duodenal-ulcer patients: release by secretin. The antitumor activity of trastuzumab observed in human gastric cancer models warrants consideration of its use in clinical treatment regimens for human gastric cancer as a single agent or a combination drug with various chemotherapeutic agents.

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This case was further investigated by genetic analysis, which came to demonstrate the limited usefulness of genetic testing in the diagnosis of LVNC. Protective effects of docosahexaenoic acid in staurosporine-induced apoptosis: involvement of phosphatidylinositol-3 kinase pathway. The findings imply that higher levels of treatment may lead to an increase of epidemic size, and the extent to which this occurs depends on other factors such as the rates of vaccination and resistance development. Yersinia effector YopO uses actin as bait to phosphorylate proteins that regulate actin polymerization. has undertaken a wide programme for evaluating and testing new insecticides.

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The aim of this study was to assess the performance of three bonding agents in preventing microleakage of class V cavities prepared and treated by Er:YAG laser associating with acid etching. Histopathological study of the kidneys revealed crowded glomeruli and only few differentiated proximal convoluted tubules in the inner cortex, abnormally differentiated microcystic tubules and microcystic glomeruli in the outer cortex.

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The median waiting time between triage and being seen by a physician was 35.0 min (range 1.0-325.0 min). ON THE PROBLEM OF EARLY RECOGNITION OF GYNECOLOGIC CANCER BY ENZYME TESTS (GLUCOSE-6-PHOSPHATE AND 6-PHOSPHOGLUCONATE DEHYDROGENASE) Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress. The first of these activities is the development of Adaptable Multi-Interface COmmunicator (AMICO):WEB, an infrastructure that facilitates efficient reuse and integration of open source software components into the Web environment. Sciatic neuropathy is a rare but serious complication following surgery performed in the sitting position.

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Population forecasts and national survey data were used to inform future predictions of care required. The most plausible mode of inheritance of myopia seems to be polygenic with variable expressivity, and shows gene dosage effect. When the drug was administered to euthyroid animals, serum concentrations of thyroid hormones were decreased, whereas the hepatic LPO increased indicating a drug induced toxicity in euthyroid subjects. The origin of the formation of this core microstructure can be explained by Marangoni motion on the basis of the temperature dependence of the interfacial energy, which shows that this type of powder can be formed even if the cooling rate is very high.

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Recent studies have shown that human perception of body ownership is highly malleable. It is important to verify factors determining the removal efficiency of viruses with MF membranes. Latent group a allotypes were detected with a sensitive radioimmune inhibition assay.