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Psychophysical assessment of a patient with Tolosa-Hunt syndrome. Results emphasize the pleiotropic nature of gup1Delta, and are consistent with a role of Gulp1p in connection with several pathways for cell maintenance and construction/remodelling. This article reviews the preclinical findings regarding the pathophysiology of late radiation-induced vascular damage, and discusses the clinical incidence and risk factors for each type of vasculopathy. This was associated with a marked increase in pulmonary vascular resistance and was felt to be secondary to pulmonary congestion, the pathogenesis of which is not fully understood. Paradoxically, these diets also induce lipogenic gene expression in rodent liver.

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In the patients, after radical beam therapy, SI and serum copper tended to normalization, in parallel with the abating of the morbid process. Neurohistological observations on the kidney of Rattus rattus rufescens (Indian black rat) as revealed by cholinesterase technique.

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Failure of splenectomy to relieve the haematologic process is usually due to remaining accessory spleens. The superantigen gene ypm is located in an unstable chromosomal locus of Yersinia pseudotuberculosis. The neural organization of the paired pedal ganglia of the desert snail Eremina ehrenbergi.

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LLD may be seen in high rates in adult femoral shaft fracture cases treated with IMN. Toxicity of irradiated antigen was abolished until 20 times of LD(50) of native venom.

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Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome. However, no reliable radiologic assessment method has yet been agreed upon. Ten women aged 26-50 years with SD and Fitzpatrick skin types III-V were enrolled in the study. We report the 3.7-Mb draft genome of Acinetobacter oleivorans strain PF1, a hydrocarbonoclastic Gram-negative bacterium in the class Gammaproteobacteria, isolated from poplar trees growing on a diesel-contaminated plume at the Ford Motor Company site in Genk, Belgium. Evaluating the evidence for targeting FOXO3a in breast cancer: a systematic review.

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Mutant mammary tissue displayed precocious lobulo-alveolar development, excessive ductal branching, delayed involution and severely reduced apoptosis. A total of 90 consecutive patients with thyroid nodules who were referred for surgical treatment were examined in this prospective study.

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The cholesterol concentration of the other lipoprotein classes showed no significant trend. Space flight effects on antioxidant molecules in dry tardigrades: the TARDIKISS experiment. Moreover, the prevalence in leaves of substances acting on peripheral benzodiazepine receptor suggests the possible utilisation of leave extracts as chemopreventive agents.

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Improved organ preservation techniques will decrease ischemia-reperfusion injury (IRI) contributing to PGD. The utility of the concept is discussed in relation to the development of new psychological models and interventions for tinnitus severity.

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Preparation effects on the clotting activity of fresh frozen plasma (FFP) The purpose of this study was to investigate the osteogenic properties of partially demineralized bone matrix in clinically relevant and realistic conditions.

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Computer simulations that model the transmission imaging system optimized the system resolution and tested the validity of a equation for the geometric efficiency of the line source collimator (LSC). Synaptic degeneration is thought to be an early pathology of neurodegeneration in glaucoma and precedes RGC loss. Taken together, these experiments demonstrate the compensatory capacity of the adult brain to injury and should lead to a new generation of studies aimed at enhancing the neuronal proliferative response. Disseminated intravascular coagulation was suspected with a positive fungal serology. The livers, pancreases and gallbladders of these cats were harvested for histological examination.

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One step further is the water-solubilization of the cavity-complex. Combined immunohistochemistry and autoradiography suggests that the majority of beta 2-adrenergic receptors in the rabbit, rat, and human optic nerve are expressed by astrocytes. This phosphorylation was associated with improved removal of residual damage 24h after irradiation. The risk factors that predispose a patient to a postoperative spinal epidural hematoma have not been identified. The liposomes appeared to be useful carriers for these drugs to retard their in vitro release in tear fluid and perhaps sustain or control their release in the eye for better therapeutic efficacy.

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In addition, results of recent efforts to increase levels of peroxisomal catalase and restore oxidative balance in cells will be discussed. To evaluate the safety and efficacy of sorafenib in real-life clinical practice conditions and to assess the influence of Child-Pugh class B on safety and efficacy. Psychological problems of pre-school children in an inner urban area. In addition, we reveal that ScPex25p acts in concert with Pex3p in the initiation of de novo peroxisome biogenesis from the ER.

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Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) can be fatal, and abnormalities in the coagulation system of patients with AE-IPF have been reported. Dynamic Change of Cellular Localization of Microtubule-Organizing Center During Conjugation of Ciliate Tetrahymena thermophila. Adult rat hepatocytes grown in a primary culture showed a homogenous actin distribution during the first 24 hr in culture as seen with anti-actin antibodies in indirect immunofluorescence microscopy. The use of a syncytium model of the crystalline lens of the eye as a new tool to study the light flashes phenomenon seen by astronauts.

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Primary malignant lymphoma of the uterus and broad ligament: a case report and review of literature. Twenty-four permanent maxillary and mandibular laterals from six, 3-4-year-old monkeys (macaca fascicularis) were used in the experiment. Mothers of a child with autism spectrum disorder have more psychiatric disorders after the birth of their child.

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Other end-points included assessments of safety and of quality of life using the Child Health Questionnaire Parent Form 28 (CHQ-PF28). The aim of the present study was to clarify the clinicopathologic characteristics of and optimal treatment for the residual cancers after EMR.

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To explain the whole clinical and laboratory picture, we hypothesize a connection between tumor immunohistochemical profile, complement consumption, and hemolytic anemia. We propose a method for long-term cleft results evaluation, with the use of periosteal graft. Sensibility was supplied by the median nerve and circulation was furnished by the radial artery and the cephalic vein. AN ALTERED-CAST PROCEDURE TO IMPROVE TISSUE SUPPORT FOR REMOVABLE PARTIAL DENTURES. The eligibility of complex congenital heart disease (C-CHD) patients for subcutaneous implantable cardioverter-defibrillator (S-ICD) has yet to be determined.

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Studies with different types of visual analog scales for measurement of pain. Social science investigations of medical ethics pay attention to the former, while feminist critiques of medical ethics are concerned with exposing and eradicating cultural biases against women.

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COMPARISON OF THE EFFECT OF VARIOUS WEIGHT TRAINING LOADS ON STRENGTH. Between September 1999 and February 2000, 11 patients underwent endoscopic-assisted septorhinoplasty, and 18 patients underwent traditional closed rhinoplasty. Therefore, the antigens which were different between the virulent and avirulent clones were suspected not to be protein antigens.

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On anatomical grounds, it is argued that the relatively small-brained and lightly built Dmanisi hominins may be ancestral to African and Far Eastern branches of H. Difference in latitude between orchards increases the importance of the geographical origin on the virgin olive oil chemical composition while full irrigation decreases the impact of the cultivar. The enzyme was generally resistant to proteolysis and denaturants including aliphatic alcohols. The scientific quality of articles was assessed using validated scales. Constitutive association of rhodopsin is promoted by a reduction in membrane thickness (hydrophobic mismatch), but also by an increase in protein/lipid molar ratio, showing the importance of interactions extending well beyond a single annulus of boundary lipids.

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Developmental kindling can be used as a model to study brief seizures early in life. The GRK2/3 immunoreactivity was found at approximately 80 kDa in a variety of cells, including salivary duct, salivary gland and eye. GS-1339 IN THE TREATMENT OF HYMENOLEPIASIS AND OTHER INTESTINAL PARASITIC DISEASES The histology of the testoids is very heteromorphic and considerably different from that of a normal testis. Polymorphisms in the N-acetyltransferase 2 (NAT2) gene influence the rate of metabolism of aromatic and heterocyclic amines present in tobacco smoke.

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The feedback from the video playback of the exercise and the feedback from fellow students and teachers enhanced the learning experience. Alcoholism and derelicts in the inner metropolitan region of Sydney. We suggest that patients with disease duration of less than 36 months only are suitable for therapeutic trials of RA and that the follow-up time should be at least 18 months if radiological assessment is used.

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It is speculated that D2 might be involved in the axonal-dendritic recognition process during synaptogenesis. Current treatment is aimed at slowing the inevitable progression of lung disease, rather than halting it, or preventing its onset. For over two decades, biochemical and enzymatic properties of PYRase have been investigated. Extracellular S-nitrosoglutathione, but not S-nitrosocysteine or N(2)O(3), mediates protein S-nitrosation in rat spinal cord slices.

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Respondents rated multiple workplace health indicators in terms of perceived importance and perceived performance. This supported hybrid bilayer membrane is rugged, easily and reproducibly prepared in the absence of organic solvent, and is stable for very long periods of time. Importantly, Ulk1-dependent phosphorylation of Ser(6) in the LYPSL prevents the interaction of syntenin-1 with ubiquitin. Asymmetrical dimethylarginine regulates endothelial function in methionine-induced but not in chronic homocystinemia in humans: effect of oxidative stress and proinflammatory cytokines.

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While average drug concentrations in brain adjacent to tumor are lower than those within brain tumors, very small numbers of tumor cells may be capable of inducing local leakiness in blood vessels, and there is little information on drug concentrations achieved in individual tumor cells within the brain adjacent to tumor. A similar correlation of -0.81 (p less than 0.05) was observed for angiotensin II in control animals. Despite their equal contributions, the two methyl groups are recognized differently by MBD1. A wide array of federal mandates have a profound impact on the use of racial and ethnic categories in biomedical research, clinical practice, product development, and health policy. Factors affecting the accuracy of estimated mean absorption times and mean dissolution times.

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Building research capacity in family medicine: evaluation of the Grant Generating Project. DNurbs (dee-in-urbs) are a small number of bicubic patches wrapping each base pair in complementary DNA.

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Thiol-epoxy click polymerization for preparation of polymeric monoliths with well-defined 3D framework for capillary liquid chromatography. Experimental and other evidence indicate that antibiotics, by modifying the intestinal microflora, affect the intestinal metabolism and enterohepatic circulation of estrogens.

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This relatively simple purification method produced a single band on analysis by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), which indicated that the SOD protein obtained attained to higher purity and specific activity. Ventilation tubes in the treatment of otitis media in young children remain controversial.

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He was found to have a papillary fibroelastoma on his tricuspid valve, which was successfully resected. The purpose of the present study was to determine whether the susceptibility to arrhythmia and electrical abnormalities persists after regression of hypertrophy in an animal model of LVH. Characterization of rotavirus infection in a hospital neonatal unit in Pretoria, South Africa. The MDRD and CG equations labeled more participants as having decreased GFR than did Scr alone.

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Encephalocraniocutaneous lipomatosis: an uncommon neurocutaneous syndrome. This study investigates the rate of infectious and thromboembolic complications in shoulder arthroscopy and their association with pharmacologic prophylaxis. In occupational exposures, populations are simultaneously exposed to a mixture of chemicals. Change in platelet count in patients with hypersplenism subjected to liver transplantation.

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An adenosine/uridine (AU)-rich element (ARE) is at the heart of a first regulatory system that promotes the rapid degradation of a multitude of cytokine and chemokine mRNAs. A formic acid extract of calf thymus was acetone precipitated, extracted with acidic methanol and precipitated with ether. The model is set up for quasi-static displacements but it nevertheless captures both reversible and irreversible behavior (Haines jump, pore body imbibition). Congenital left ventricular out-pouching, consisting of left ventricular aneurysms, left ventricle diverticulae, and double-chambered left ventricle, is a rare cardiac malformation. The incorporation of small, permanent, rare-earth (SmCo5) magnets with the coil assemblies has eliminated the unreliable mechanical supporting devices.

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Lapatinib was tested against the xenografts of the PPTP in vivo panels using a twice-daily oral administration schedule for 6 weeks (5 days on, 2 days off) at a dose of 160 mg/kg (320 mg/kg/day). Analysis of the particular positions of these two motifs in view of the available data on occupancy of tRNA-binding sites and structural changes in the ribosome during the elongation cycle suggests a distinct role for each motif in tRNA translocation. Femoral neck narrowing following hip resurfacing using posterior and Ganz approaches at two years. The patient is a 51-year-old man who had diabetes mellitus for eleven years.

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Mobility function of the elderly living with their children and its relation to the home health care system in Tokyo. We sought to generate high-titer H5N1 antibodies in healthy volunteers for the purpose of developing hyperimmune intravenous immunoglobulin.

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The probability of not enrolling high-loss cases is found to be high, indicating that the biased selection in HMO plans actually increases the overall cost of running the Medicare program. Several important topics in public health ethics have also been highlighted. Research on the pathogenesis of experimental emphysema has involved studies of the distribution of and destruction of elastin in the alveolar interstitium. Dihydrofuran-fused perhydrophenanthrenes were synthesized by means of o-quinodimethane chemistry with high generality and stereoselectivity, and found to exhibit potent anti-influenza activity.

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N-butyl-2-cyanoacrylate tissue adhesive was injected into the preretinal space of rabbit eyes to study potential toxicity to the retina. At low electrolyte concentrations the single-channel conductance is much larger in the negatively charged membrane than in a neutral membrane. Following previous vacuum-assisted closure therapy, the patients undergoing skin transplantation were prospectively randomized into two groups.

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In addition, Pax6 disruption led to apoptosis of lens epithelial cells. Radiation-induced sarcoma (RIS) is a rare complication following therapeutic external irradiation for lung cancer patients. As compared with the time of maximum concentrations (tmax) for BPD, the PRL tmax was later after i.v. The cause of the cardiac insufficiency was established or confirmed in 54 of 58 patients. A 35-year-old woman was admitted to our hospital because of an abnormal chest radiograph.

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Different AhR binding sites of diterpenoid ligands from Andrographis paniculata caused differential CYP1A1 induction in primary culture in mouse hepatocytes. Both the number and volume fraction of GGT-positive AHF were significantly lower in rats cotreated with E2 regardless of TCDD exposure compared with corresponding non-E2-treated groups and were unaffected by TCDD. By immunocytochemistry and immunoblotting, we examined normal and neoplastic human tissues with polyclonal antibodies raised against selected peptide regions of proprotein convertase-2 and -3 (PC2 and PC3), two proteases that have been shown to selectively cleave neuroendocrine precursor molecules at pairs of basic residues. Preoperative chemotherapy and radiation for advanced esophageal carcinoma: comparison between once a day radiation and hyperfractionation, a single-institution experience. Prevalence of musculoskeletal symptoms and associated factors: A cross-sectional study of metal workers in Bangladesh.

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Nonetheless, some TSE agents are able to cross this barrier and infect new species, with devastating consequences. We present two such cases in which the diagnosis was initially established on computed tomography, which showed mature skeletal structures including vertebrae and long bones in addition to fat. Piercing or laceration of vessels transversing the abdominal wall during trocar placement is generally the cause.

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Steroid-free immunosuppression was confirmed to be safe and feasible for HCV-positive recipients in LDLT, and was associated with suppressed HCV replication and HCV recurrence after LDLT. In contrast, the expression of STAT1, STAT3, and STAT5b, as well as phosphotyrosine-STAT3 were relatively preserved in these explanted TGs.

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We investigate experimentally the formation and the transportation of a heap formed by granular materials in an inclined and vertically vibrated container. However, PLRP2-positive CTLs (induced with many lots of IL-4) were unable to mediate lipid-dependent cytotoxicity. Costunolide and cisplatin were examined in platinum-resistant human ovarian cancer cells. The SenseCam review procedure resulted in significantly more details of an event being recalled, with twice as many details recalled at 6 months follow up compared to the written diary method. Resection of the fibrous band and correction of the mitral valve using the accessory fibrous band was performed.

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Drug blood concentrations in superior sagittal sinus and aorta were measured serially. A regulator of Aspergillus fumigatus extracellular proteolytic activity is dispensable for virulence. At this time, the primary method used for identifying a specific organ or primordium is whole mount in situ hybridization with labeled antisense RNA probes specific to a gene that is expressed in the organ of interest.

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Sporogony, development and ultrastructure of extrinsic stages of Plasmodium mexicanum. Evaluation with transoesophageal echocardiographic and real time three-dimensional imaging. The BMPs 2, 4 and 7 are expressed strongly in the AER, whereas BMP-5 is expressed as a weak signal in the distal mesoderm during the early stages of limb development.