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THE EFFECT OF IONIZING RADIATION ON MELANOCYTE-STIMULATING AND STEROIDOGENIC ACTIVITIES OF CORTICOTROPIN. We show that the issues involving censored data can be circumvented by reformulating the problem as a standard Poisson regression problem.

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A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies. By considering the transitions of membrane ionophores, a faithful quantitative explanation of the heat of activity is obtained. The main observation from this study is the higher radiosensitivity of the submandibular gland compared to the parotid gland for late effects after fractionated irradiation. Use of in-house, full-colour printed three-dimensional model for training in endoscopic periradicular surgery for molar radicular cyst.

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A fragment of the VP2 gene of the virus was analyzed using polymerase chain reaction (PCR), restriction endonuclease (RE) and DNA sequence analysis. Although some statistically significant changes in the soft tissue profile were found, the magnitude of the changes may not be perceived as clinically significant.

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Correlation between confirmed sites of neurological lesions and abnormalities of far-field auditory brainstem responses. hemionus virus and representatives of other major groups of mammalian type C viruses.

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We report a case of Roux loop obstruction occurring 4 years after a lateral pancreaticojejunostomy (LPJ) for chronic pancreatitis. Future larger prospective studies are needed to definitively determine whether PRP should be used with meniscal repair.

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Ferric ion, ferrocyanide, and inorganic phosphate as cytochemical reactants at peripheral nodes of Ranvier. Two rare clinical manifestations of coenurosis in sheep are reported. Topology of glutathione-insulin transhydrogenase in rat liver microsomes. Smoking habits among patients diagnosed with oral lichen planus.

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The NICA-Donnan model gives a reasonable estimation of dolomite saturation index in a wide range of DOC. Because a cure is not a reasonable goal for patients with end-stage renal disease (ESRD), optimal physical and mental health functioning are primary objectives of care and major determinants of health-related quality of life, morbidity, and mortality.

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Paper-based microfluidic systems produced in this way retained the flexibility of paper and a variety of patterns could be formed. Typically the product of fracture, dislocation, or crush injuries, pediatric peripheral nerve injuries may be difficult to accurately characterize. The project was conducted under the supervision of the Department of Physiology, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia. In the transfer phase, subjects could transfer (1) the whole sequence of one region, (2) two partial sequences of adjacent regions, or (3) single components. Lactate transport mechanisms at apical and basolateral membranes of bovine retinal pigment epithelium.

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Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells. We collected bronchial biopsy samples and epithelial brushings from 24 smokers with and without airflow obstruction and 19 nonsmoking healthy control subjects. Conduct Disorder and Socialized Aggression subscales were characterized by high Psychoticism, Impulsivity, and Lie personality scores, by lower heart rate levels, and by more errors on a continuous performance reaction-time task. Mustard oil enhances spinal neuronal responses to noxious heat but not cooling. Biosilicification sets the standard for the localized in vitro precipitation of silica at low orthosilicate concentrations in aqueous environment under ambient conditions.

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The V0 interneuronal population is derived from Dbx1 expressing progenitors. Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort. Age related changes to perceptual surround suppression of moving stimuli.

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Evidence for the two-step binding of ATP to myosin subfragment 1 by the rapid-flow-quench method. With load 0.18--0.31 mg surfactant/mg d.w./day microorganisms were dominated by Pseudomonas. Some studies of endometrial cancer suggest that the inverse association with smoking is limited to certain groups of women, such as those who are postmenopausal or those taking hormone-replacement therapy. However, following multiple-day infusion estimates were obtained that were inconsistent with those from the short infusion. Such an incomplete carbohydrate portion seems also compatible with the finding that glomerular extracts did not stimulate erythropoiesis in hypoxia exposed mice.

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Absorption of tranexamic acid as a prodrug in healthy volunteers. Interestingly, while there was a strong association between peripheral measures of neuropathy, no higher incidence of cardiac neuropathy in patients with increased foot pressure profiles was found. MADURA FOOT DUE TO MADUROMYCES (MADURELLA MYCETOMI) (NON-SUPPURATIVE FORM) The onset of apoptosis and associated events occurred in a time-dependent fashion. We now explored the effect of two different statins, simvastatin and atorvastatin, in the activation of the octamer transcription factor Oct-1 on the monocytic cell line THP-1.

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The most active combination contained permethrin and neopinamin in a ratio of 9:1. The influence of glucocorticoids during the neonatal period on the development of play-fighting in Norway rat pups. In order to avoid ambiguity and potential subjectivity in image interpretation we suggest that data distribution plots are used to aid shading approaches and that extreme care is taken to use the most appropriate false-shading for the biomedical question under investigation. The basic idea, chemistry, different structural modifications and their effects on the antiviral potency of the cycloSal-d4TMP triesters have been discussed in this review.

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Development of a new active ingredient for the treatment of psoriasis with synthesis from plant raw materials: RGH-4417 This approach often asks for the development of new methods, tools, and materials to prove them, and it is exactly this aspect, both, with respect to experiment and theory, that is a trade mark of our institute. The effects of gastrectomy, especially total gastrectomy, on the serum levels of 25-hydroxyvitamin D and vitamin D-binding protein and on mineral metabolism were examined. SIMCA effectively selected variables that contribute to tea categorization. Medical history including a previous MI and stroke, and dates of these events were obtained by means of a structured telephone interview.

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The development of the Self-Rating Inventory for Posttraumatic Stress Disorder. Duraplasty with in situ galeal tissue is a simple, safe, and effective technique to reconstruct dural defects in growing skull fracture, which avoids the risky dissection of the brain tissue. To analyze word prediction software settings used by HRP for people with cervical SCI. Some discrepancies exist between in vivo studies with animals and clinical studies, or between clinical studies, which are likely due to disparate doses of RSV, experimental settings, and subject variation.

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Glucose-6-phosphate dehydrogenase and lactate dehydrogenase activities and lactate dehydrogenase isoenzyme spectrum in human myocardium after sudden death caused by acute alcohol intoxication and ischemic heart disease Only 1 microM selenous acid increased the frequency of binucleated cells containing micronuclei (BNMN) in blood lymphocytes, while all three selenium compounds increased BNMN in TK6 cells.

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Here, we derive a solvation model with no empirical parameters for the dielectric response by taking the linear response limit of a classical density functional for molecular liquids. Necrotizing fasciitis caused by Klebsiella pneumoniae has been described in Southeast Asia, but has only recently begun to emerge in North America. The effectiveness of Penicillium chrysogenum was evaluated for reducing Cr(VI) from the wastewater of a chromium electroplating plant. Spin blockade only occurs in one bias direction when there is asymmetry in the electron population of the two dots, leading to current rectification.

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Each of the AKAP family members utilizes unique targeting domains specific for a particular subcellular compartment. Thus, both the structure and assembly of the TMV CP function as determinants in the induction of disease and resistance responses. However, the effects of prebiotics on the human gut microbiota are incomplete as most studies have relied on methods that fail to cover the breadth of the bacterial community. Treatment incidence of and medical utilization for hospitalized subjects with pathologic fractures in Taiwan-Survey of the 2008 National Health Insurance data. Our work suggests cremophor EL, a relatively nontoxic lipophylic solvent, may have a direct effect on membrane permeability, although other mechanisms cannot be ruled out.

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Hand preferences in preschool children: Reaching, pointing and symbolic gestures. Development and validation of a rapid column-switching high-performance liquid chromatographic method for the determination of Lamotrigine in human serum. Holmium laser lithotripsy can be effective for retained bile duct stones, but it requires direct visualization during the procedure for safe and effective fragmentation.

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It was confirmed by Ouchterlony test that the antiserum adsorbed successively with monkey serum or anti-LSC adsorbed directly with monkey serum reacted with only human serum but not with mammalian ones. Moreover, an up to twofold-higher number of bacteria adhered after growth in bile for E. However, there is limited evidence to suggest which subpopulations are at higher risk for arrhythmia development due to increased air pollutant exposure.

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We have demonstrated the use of elementary modes and the linear programming to quantify a metabolic network. Alcohol--orally given in concentrations from 1 to 4 g/kg body-weight--leads to a reduction of mast cells in the guinea pig lung. The IR/MAR gene amplification system extends our understanding on the mechanism of gene amplification and the behavior of amplified genes. Both systems are mutated in several different forms of inherited muscular dystrophy and cardiomyopathy.

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Fast inward current properties of voltage-clamped ventricular cells of embryonic chick heart. Since venous occlusion results in the release of plasminogen activator from the vascular endothelium into the blood, these findings suggest that the reduction in the level of spontaneous fibrinolytic activity after major operations is the result either of exhaustion of the vascular endothelium of plasminogen activator or defective synthesis and release of this enzyme from the endothelium. We report on the experimental observations of a period-doubling route to chaos and a total mode-locking between two lowest-order lateral modes of a GaAs ridge wave-guide diode laser at 795 nm. Treatment with 5-fluorouracil caused inactivation of plaque forming ability in cells induced with methotrexate. Purified cofactor-protein S caused a large enhancement in the rate of inactivation of Factor Va by activated protein C in the presence of phospholipid.

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The addition of antibiotics to autologous spheroid cultures inhibited the synthesis of matrix proteins. Two different approaches to health care reform in the United States.

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In contrast, aspirin-treated PGHS-2 (ASA-PGHS-2) no longer forms prostaglandins but retains oxygenase activity forming 11(R)- and 15(R)-hydroperoxyeicosatetraenoic acid and also retains the EPR line-shape of the native peroxide-induced 29-30-G wide singlet radical. Signaling through CXCR2, CXCL1 inhibited oligodendrocyte precursor migration.

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The elastic shear modulus (transient localization length) grows (decreases) exponentially with volume fraction in a manner that becomes stronger as particle dimensionality increases. PREVENTION OF CUTANEOUS CALCIPHYLAXIS IN CALCIUM-DEFICIENT RATS. Endothelium-dependency of yohimbine-induced corpus cavernosum relaxation. This showed that pre-incubation of IM serum with NHS caused a significant reduction in IgM positive cells compared to that observed with IM serum diluted in CFD alone.

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The clinical significance of these changes and the differential effects on very small LDL 4a in patients with higher vs lower TG remain to be determined (clinicaltrials.gov, NCT00325455). Over 7 h of incubation, the fluorescence generated from the hydrolysis of CMUG by E. A benthic toxic dinoflagellate identified as Prorocentrum lima (Syn. Patients with jaundice require rapid diagnosis and treatment, yet such patients are often subject to delay. However, since MTC is a neuroendocrine neoplasm, we considered the possibility that cytotoxic drugs previously used in the treatment of these tumours could also have activity in MTC.

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Patients with necrosis were effectively treated with repeated pulse therapy judging by immunological activity and the decrease in proteinuria at an early stage, but responded poorly to oral steroid therapy. Evaluation and localization of thyroid tissue using an intraoperative-type solid-state radiation probe. However, mouse and rabbit cytochrome c also elicit antibodies to the area of residue 62 in rabbits and mice, respectively, and these antibodies still bind more strongly to the glutamyl-than to the aspartyl-containing determinant.

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There was little or no relation between the rate of PB withdrawal, other drug therapy, or initial PB level and the ratio of highest seizure frequency to mean seizure frequency. In most tissues, ACELA was similar in lampreys acclimated to freshwater (FW) and seawater (SW). Quorum-sensing regulation of gene expression: fundamental and applied aspects and the role in bacterial communication First trimester diagnosis of forked cord in monoamniotic twin pregnancy. In this case there is a fixed, charge-free space near the membrane, depending on coat thickness, ionic strength and membrane charge/surface coat charge ratio.

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Neural and glial plasticity, ranging from changes in molecular expression and receptor phosphorylation to profound morphological reorganization, has been described under these conditions. Effects of indomethacin suppository and lidocaine pomade for the relief of post-episiotomy pain. Human T-cell leukaemia/lymphoma virus type 1 (HTLV-1), a causative virus of adult T-cell leukaemia/lymphoma (ATLL), is known to be transmitted by breast-feeding. The second stage system was suggested earlier to provide a useful analog of the behavior of natural and agricultural ecosystems subjected to perturbations, but for this it needs the capacity for self-organization.

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Heat shock proteins (Hsps) are essential, highly conserved proteins that are needed for normal cell growth and maintenance, and expression of Hsps has been detected during embryogenesis in various organisms. A second smaller peak in the mean total egg counts occurred in both groups in May 1979. Most cases of pelvic schwannoma have been reported in the gynaecological and urological literature due to their presentation as a pelvic mass or from urinary tract compression. Pre-induction of HSP72 may provide therapeutic strategies for nephrotoxicity induced by GM. The levels of inflammatory cytokines and histones H1, H3, and H4 in plasma and lung tissue were measured by ELISA.

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Laryngeal dysplasia is a common disease entity that remains clinically frustrating because functional outcomes are balanced against oncologic results. A retrospective analysis on the basis of clinical disease courses and findings (image documentation, questionnaires, pulmonary function tests) covering an examination period of 10 years, was performed on 40 patients with stenosising lesions and a mean age of 54 years. Glycodendrimersomes with programmable surface display of glycan, together with artificially engineered galectins, were used to understand the physiological significance of human lectins with homodimeric and tandem-repeat-type displays.