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cDNA cloning and efficient mitochondrial import of pre-mtHSP70 from rat liver. Understanding how emotion expression influences decision-making is important as a practical matter. In addition to low blood glucose, affected skijumper mice have lowglycogen and ketone levels.

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Planar bilayer experiments reported here confirm pore formation by these compounds but identify more than one conductance state for each. A cation-pi interaction between serotonin and Trp183 of the serotonin channel 5-HT(3A)R is identified for the first time, precisely locating the ligand-binding site of this receptor.

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Ambulatory sleep recording in a healthcare network: a feasibility study. To explore gender and sex differences in experiences of transitioning to adult health care among young adults with acquired brain injury (ABI) who take part in a coordinated model of transitional care. Previous studies have indicated that hormonal control is essential for plant root growth. Enhancing effects of fluoride-containing ceramic implants on bone formation in the dog femur.

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How can such observed Raman scattering anisotropy be related with a biologically relevant molecular arrangement? To determine the effect of respiration-induced density variations on the estimated dose delivered to moving structures and, consequently, to evaluate the necessity of using full four-dimensional (4D) treatment plan optimization. To assess the value and limitations of using transoesophageal echocardiography as the sole diagnostic test in patients with suspected thoracic aortic dissection. In the 7th edition of the TNM Classification of Malignant Tumors, the number of involved LNs is included in the definition of pN factors in breast, stomach, esophageal, and colorectal cancer, and the pN status significantly correlates with prognosis.

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Detection of anatoxin-a(s) in environmental samples of cyanobacteria by using a biosensor with engineered acetylcholinesterases. Today, however, the potential use of non-meat proteins makes it very difficult to estimate the muscle protein content of the meat product. The proposed models are also shown to yield a slightly improved performance than a newly developed second derivative-PLS model without incurring the shortcoming associated with the derivative approach in not providing interpretable results and in degrading the SNR of the spectra at a faster rate.

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This problem may be solved if positive epistasis selects for reducing the rate of recombination between such traits, but this requires sufficiently strong epistasis. Think locally, act locally: detection of small, medium-sized, and large communities in large networks. By comparison, the D313A mutation results in a shift in a shift in the pH optimum and a modest decrease in activity that can be rescued by using azide as an exogenous nucleophile.

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However, the formation of ternary complexes with both chaperone machineries is impaired, as Hsp70 and Hsp90 compete for CeHop interaction sites, in particular as Hsp90 binds to both TPR domains simultaneously and requires both TPR domains for ATPase regulation. Longitudinal quantification of incipient carious lesions in postorthodontic patients using a fluorescence method.

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Osteochondrosis may present as a separate disease or be one of the stages of a dystrophic process coursing in the presence of cartilagenous nodes of deforming spondylosis. We use one empirical measure, genetic diversity at the colony periphery, to parameterize our models and show that we can then accurately predict another key variable: the degree of short-range cell migration along an edge.

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Effects of fibroblast growth factor 2 on osteoblastic proliferation and differentiation by regulating bone morphogenetic protein receptor expression. At later ages (2- and 7-months old) the number of spines was greater in rats exposed perinatally to carbon monoxide than in control rats of the same age. We demonstrate here that synthetic retinoids inhibit 12-O-tetradecanoylphorbol-14-acetate-induced transcription from the stromelysin AP1 motif through RAR alpha, -beta, and -gamma. Ripening-dependent metabolic changes in the volatiles of pineapple (Ananas comosus (L.) Merr.) fruit: II. Selective chemical probes are required to establish the dynamic function of individual PRMTs.

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The peptidoglycan (PG) of Lactobacillus plantarum contains amidated meso-diaminopimelic acid (mDAP). Lymphoid depletion and necrosis in germinal centres were consistently present.

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Male internal genital organs of the damselfly Pseudagrion rubriceps Selys (Odonata: Zygoptera). Calpain was also required for the microtubule-mediated turnover of adhesive complex sites after nocodazole wash-out, suggesting that calpain may mediate focal complex disassembly downstream of microtubules. Further virus challenge tests were carried out on guinea pigs and swine, high-titer neutralizing antibodies were produced and the CP-EP141-160 VLP vaccine could protect most of the animals against FMDV. Whole-body periodic acceleration (WBPA) has been developed as a passive exercise technique to improve endothelial function by increasing shear stress through repetitive movements in spinal axis direction.

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Neural substrates of semantic relationships: common and distinct left-frontal activities for generation of synonyms vs. Understanding the length dependence of molecular junction thermopower. Our results suggest that resveratrol might act on other cellular targets as well as NF-kappaB at the initial stage of gene expression. Path analysis, with standard errors determined by methods appropriate to small samples, suggested that self-efficacy completely mediated the relationship between stage of change and unprotected intercourse acts.

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Characteristics of ClC7 Cl- channels and their inhibition in mutant (G215R) associated with autosomal dominant osteopetrosis type II in native osteoclasts and hClcn7 gene-expressing cells. Furthermore, Hck activity has been associated with virus infections including HIV-1. Two of the cis-encoded sRNAs were associated with genes encoding enzymes involved in lipid metabolism, desA1 and pks12.

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No correlation was found between the antibiotic levels in the serum and the levels in the saliva. Dog ownership, abundance and potential for bat-borne rabies spillover in Chile.

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In order to successfully achieve change the engagement of those delivering care is necessary. In WiDr cells deoxyinosine (0.1-1.0 mM) clearly potentiated the growth inhibition by 0.1-0.5 microM 5-FU after 24 h of culture, but growth between 24 and 48 h was normal. The combined findings raise the intriguing possibility that biliary FGF19 has a signaling function in the biliary tract that differs from its established signaling function in the portal circulation. To investigate the causal associations between family relationships, family functioning, social circumstances and health outcomes in young children with cystic fibrosis. Functional state of the kidneys in patients with tuberculosis of the lungs during the development of drug intolerance

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Fortilin specifically interacted with MCL1 both in vitro and in vivo. Age-related changes in aldehyde dehydrogenase activity of rat brain, liver, and heart. The hepatic primordium consisted of cranial and caudal portions. Phase locking of an array of three fiber lasers with this configuration has been demonstrated experimentally, and obvious interference patterns and stable coherent output have been observed. Treatment of the particulate cytoplasmic fraction with nonionic detergents, using three different protocols designed to isolate the cytoskeleton matrix, indicated that part of Nef was sensitive and part was resistant to detergent solubilization.

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Canakinumab for the treatment of chronic obstructive pulmonary disease. The alternative application of developed formalism as the first order theory to treat the multiple inclusions is suggested.

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The prognostic significance of positive peritoneal cytology and adnexal/serosal metastasis in stage IIIA endometrial cancer. Randomized trials comparing the efficacy of EVT and noninvasive therapies, such as medical therapy (MT) and supervised exercise (SVE) in patients with intermittent claudication were identified by a systematic search.

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nero mutations affect cell and organ size, bromodeoxyuridine incorporation, and autophagy. Pediatric sialolithiasis distinctive characteristic in radiological imaging.

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Reactive haemophagocytic syndrome (RHS) is a disorder characterized by systemic proliferation of non-malignant histiocytes occurring most commonly in patients with pre-existing immunological abnormalities or neoplasms. The increase of regional water and sodium content in the MCA territory is less in the dexamethasone treated group, whereas the potassium changes in the ischemic tissue showed only small differences between the two groups. Plain chest radiography and CT were performed on all patients, and follow-up CT was performed on one patient. The visual acuity and contrast sensitivity of police recruits and officers was evaluated in both normal and dim illumination conditions to determine whether officers who have had refractive surgery have compromised night vision.

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Clavulanic acid increases dopamine release in neuronal cells through a mechanism involving enhanced vesicle trafficking. THE APPLICATION OF NEGATIVE STAINING METHODS TO QUANTITATIVE ELECTRON MICROSCOPY. Interaction of drugs in this setting requires ongoing vigilance by the physician. We hypothesized that inconsistent cell growth in fermentations could be due to the quality of FBS and that different lots of FBS had varying concentrations of proteins such as growth stimulatory factors, growth inhibitory factors, and/or other proteins that may correlate with cellular growth rate. Results from those studies cannot reflect the opinions of the spectrum of persons in academia.

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In the present investigation it is shown that a reflex change in the heart activity of Protophormia flies is evoked by olfactory stimulation with several volatile substances, and particularly with those which are repellent for blowflies. Atrial fibrillation is one of the most common complications of cardiac surgery. Predicting benefit from fulvestrant in pretreated metastatic breast cancer patients.

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SDS-PAGE suggests differences between species and similarities between related species but 2-DE indicates that the protein composition of the venoms is highly complex. Uvulopalatoplasty, performed with high-frequency radio waves, was evaluated as a treatment for social snoring. Social media networks contain both content and context-specific information. Conformational studies on plasminogen activator inhibitor (PAI-1) in active, latent, substrate, and cleaved forms.

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A giant magnetoimpedance (GMI)-based biosensor was developed for detection of Escherichia coli (E. Precise identification of MHC-restricted peptides is of great significance for understanding the mechanism of immune response and promoting the discovery of immunogenic epitopes. Although use of vein patches is considered to be the gold standard for patch closure, newer generations of synthetic and biologic materials rival outcomes associated with vein patches. Patients with any of these features should undergo immuno-allergolical investigation.

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The clinical significance of this finding is the possibility to devise strategies for metabolically modulating aggressive triple-negative tumors so as to enhance their chemosensitivity in vivo. Recipient data included sex, age, cause of renal insufficiency, and time and number of hemodialyses prior to transplantation. Site-directed mutagenesis studies showed that Lys-386 of p53, the SUMO-1 modification site, is also the modification site for SUMO-2/3. Care was taken to rule out other possible causes for eosinophilic pneumonia.

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In this report, patients and controls were assessed a mean of 4 years after the first assessment to determine if depressive and manic symptoms and cognition remained stable, improved or worsened. Ejection performance was reduced with increasing sphericity, which was regionally related to a reduction in the active fiber stress development, fiber shortening, and stroke work in the midwall and subepicardial region at the midheight level in the left-ventricular wall. In order to reduce this time, the pharmaco-invasive strategy may offer rapid flow recanalization in the culprit artery and reduce the damage of the myocardium. What has emerged in recent years is that there are circumstances in which the tightly regulated balance of hydrogen peroxide producing and degrading activities in peroxisomes is upset-leading to the net production and accumulation of hydrogen peroxide and downstream reactive oxygen species. Whole body radioiodine scintigraphy with (131)I and ablation of the thyroid remnant by the administration of 80 mCi (131)I was performed.

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Repeated end-range spinal movements producing specific pain responses (i.e. Gastroresistant microcapsules: new approaches for site-specific delivery of ketoprofen. The patients were assigned to one of the three groups: A (night guard), B (mouthwash), or C (night guard and mouthwash).

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Predictions of blood flow from thermal clearance during regional hyperthermia. Interactions among species drive the ecological and evolutionary processes in ecological communities.

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Central GLP-1 is a novel regulator of chylomicron production via melanocortin-4 receptors. Acid-catalyzed cascade reactions of arylvinylcyclopropenes with acetals and aldehydes for the construction of different aromatic systems. A numerical example is provided to demonstrate the effectiveness of our theoretical results.

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FR rats pretreated with disulfiram (DSF) prior to 3.0 g/kg methanol treatment failed to display these symptoms. The sera identified four distinct Ia specificities, which were designated as Ia.2a, Ia2b, Ia.13a and Ia.13b. Genetic dissection of a stem cell niche: the case of the Drosophila ovary. Biomaterial biotechnology using self-assembled lipid microstructures.

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We have used genomic and physiological tools to understand the process and propose that analysis of catabolic signatures and nutrient levels, are crucial parameters in assessing and monitoring the performance of an effluent treatment plant. The annual incidence showed a steady downward trend of 3 per cent per year. Analysis of the pore size distributions from the N(2) adsorption data has allowed us to quantify the degree of coalescence of the particles in the matrix. NFC technology is one of radio-frequency identification (RFID) standards.

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Hormonal pathways that participate in testicular descent and the effects of chemical exposures on this process have been studied in animal models. All women diagnosed with breast cancer and treated at the Sun Yat-Sen Cancer Center between January 2000 and December 2009 were included and followed-up for occurrence and/or death from lung cancer until December 2011.

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Transplant renal artery and vein thrombosis have an early onset and a dramatic clinical manifestation and usually lead to allograft loss. Transgenic animal models have played an important role in elucidating gene functions and the molecular basis development, physiology, behavior, and pathogenesis. Gastric endoscopic submucosal dissection using novel 2.6-mm articulating devices: an ex vivo comparative and in vivo feasibility study. Major causative factor for major depression is inflammation, autoimmune tissue damage and prolonged psychological stress, which leads to oxidative stress. Extensive model simulations are compared with experimental data.

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The results of this study provide the framework for subsequent analysis of the effects of various intrinsic and extrinsic factors on neural differentiation. Finally, precise manipulation of the laser firing angle and position was implemented in order to compensate for the effects of refraction at the cell wall boundaries, and to re-establish the projections required for the reconstruction algorithm. Open-ended individual interviews were conducted with the elderly residing in LTCI, their carers, nursing technicians and nurses, directors of care, dental surgeons and managers of public health services.

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Testicular germ cell tumors with sarcomatous components: an analysis of 33 cases. Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study.

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Aggregation and gelation kinetics of fumed silica-ethanol suspensions. Although the involvement of intra-tumor genetic heterogeneity in tumor progression, treatment resistance, and metastasis is established, genetic heterogeneity is seldom examined in clinical trials or practice. This imaging modality demonstrated muscle signal abnormalities in several muscle groups and was useful in ruling out the presence of a mass and fatty degeneration of the muscle. It is found that the early hand anlage is already composed of relatively autonomous founder cells committed to different lineages. Significant differences between treatments were found for the AUC of S-ketamine and within the racemic ketamine CRI for the AUC and Cmax of norketamine isomers.