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Activity-based therapies are not a cure, but are likely to play an important role in future treatment cocktails for stroke and spinal cord injury. The effects of all-trans-retinoic acid on cell cycle and alkaline phosphatase activity in pancreatic cancer cells. Human chromosome polymorphism and disordered reproductive function.

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The complete genome sequence of a single-stranded RNA virus from the tarnished plant bug, Lygus lineolaris (Palisot de Beauvois). Cats may have higher risk than dogs for low liver GSH concentrations. Comparison of amplitudes of surface macro motor unit potentials recorded from various muscle sites. The creation of lymphoblastoid cell lines (LCLs) through Epstein-Barr virus (EBV) transformation of B-lymphocytes can result in a valuable biomaterial for cell biology research and a renewable source of DNA. The condition presented as asymptomatic bacteriuria (nine patients), dysuria or frequency (12), and fever without localizing signs (three).

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Restoration of continence remains a major challenge in patients after abdominoperineal rectal excision (APE) or with end-stage fecal incontinence. Evidence was also obtained of increased toxicity in materials of reduced size. Epithelial to mesenchymal transition (EMT) is an important mechanism for the initial step of metastasis.

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The organ specificity of CMNU is compared with that of other N-alkyl-N-nitrosourea derivatives. Proteomics and its employment in Systems Biology and other areas that require sensitive and high-throughput bioanalytical techniques greatly depend on these methodologies. However, there are no specific drugs/interventions due to unclear pathophysiology. Data from a nationwide Norwegian twin study show that the results of twin studies will be quite different depending upon the ascertainment procedure.

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Time-scale methods, or wavelet transforms, allow a time versus duration analysis to be performed whereas time-frequency methods allow spectral contents to be analyzed as a function of time. ON ABSORPTION CHANGES IN CHLOROPLASTS AND ALGAE CAUSED BY DRYING When the axons of both neurons 5R and 5L were spot irradiated neurite outgrowth resulted in the formation of a novel electrical connection between these cells.

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Immunologically undetectable human placental lactogen in a normal pregnancy. Co-stimulatory molecules can be efficiently produced as a recombinant protein in E.

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A checklist to assist in decision-making was created as a tool to assist the researcher in determining whether it is advantageous to include grey literature in a review. The purified protein could self-assemble into extensive protein filaments in vitro. The human osteosarcoma cell line MG63 was transfected with UBQLN2 siRNA and cultured under hypoxic conditions. The use of cell adhesion molecules to control morphology of developing stem cell aggregates should be widely applicable in tissue engineering.

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Primary signet-ring cell carcinoma of the lung with histochemical characterization. Sera from multiple sclerosis patients with relapsing-remitting disease and normal subjects were tested for antibody to myelin basic protein by a sensitive radioimmunoassay. It is shown that the glycogen is synthesized in the perikaryon and transferred to the terminals by means of slow axoplasmic transport.

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The excess periodate was then reduced with thiosulfate or ascorbic acid prior to the extraction of methamphetamine using a basic pH. It is necessary to recognize the rate of decrease of ADC, because it is dependent on the density of iodine contrast agents. Progressive accumulation of epigenetic heterogeneity during human ES cell culture. Although the mitoK(ATP) channel has clearly been shown to be a distal effector of delayed IPC and PPC, studies implicating it as a trigger of protection in delayed IPC are lacking. Anthracycline-based combination chemotherapy regimens are the standard therapy for patients with diffuse large B-cell lymphoma (DLBCL), but such regimens may be poorly tolerated in elderly patients.

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Combined effect of Raman and parametric gain on single-pump parametric amplifiers. Multivariate analyses, however, indicate that the excessive use of alcohol and other illicit drugs are more influential than demographic and college-specific risk factors. Few studies have compared BMI and BF, especially in patients with coronary heart disease (CHD).

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Antidepressant efficacy of the antimuscarinic drug scopolamine: a randomized, placebo-controlled clinical trial. Recombinant latex allergens are clinically reactive and can be produced in a standardized manner, which could potentially provide safe and sensitive reagents for the diagnosis and treatment of type I latex allergy.

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SIRT2 and SIRT6 are expressed in retinoblastoma, as well as in some normal ocular structures. Coexistence of congenital auricular deformities with urogenital anomalies.

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This study aims to determine circulating RNA levels of hem-endothelial marker genes in peripheral blood of preterm infants and begin to correlate these findings with prenatal complications. Pentylenetetrazole-induced seizures, in contrast, were not able to change Homer1a mRNA expression. Crystal structures of the PD-(DE)XK superfamily revealed a common alpha/beta core motif and similar active site. The key to proper disposition is an orderly approach with a good history and with a methodical examination and the use of ophthalmologic aids, such as topical anaesthetics, good light and magnification.

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Artificial sunlight exposure alone induced only a moderate skin tumor incidence (animals with at least one tumor) of 0.15 after one year, and UV-A irradiation alone induced no tumor formation. At present, the infant is 2 years old, and she is thriving normally and maintains urinary continence with spontaneous voidings. Inflammatory bowel diseases (IBD) arise from multiple causes, including environmental factors, gut microflora, immunity, and genetic predispositions. Detection of immunoglobulin G to measles virus, rubella virus, and mumps virus in serum samples and in microquantities of whole blood dried on filter paper.

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Fatigue in the scapular retractors resulted in lower shoulder-rotation-torque production. We previously identified a quantitative trait locus (QTL) on rat chromosome 5 that appeared to be primarily controlled by the sympathetic nervous system.

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The ontogeny of various cell populations defined by monoclonal antibodies in the primary lymphoid organs of the sheep. We also determined the methylation status of CpG islands associated with RASSF1-10 in a series of childhood acute lymphocytic leukaemias (ALL) and normal blood and bone marrow samples.

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Left ventricular mass regression after aortic valve replacement with the mosaic bioprosthesis. Acute calcific periarthritis associated with transient hypocalcaemia secondary to hypoparathyroidism.

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Serotonin neurons in the dorsal and median raphe nuclei (DR and MR) are clustered into heterogeneous groups that give rise to topographically organized forebrain projections. Quantitative assessment of carnitine loss during haemodialysis and haemofiltration. Human oral bacterial pathogens grow in attached multispecies biofilm communities.

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Necrotizing granulomas in B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma. These results indicate that hypoxia can protect HTDEC against IFN-gamma-mediated cell death and antiangiogenic activity, and suggest that improvement of tumor oxygenation may potentiate the efficacy of anti-cancer therapies specifically targeting the inhibition of tumor angiogenesis.

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The IL intake may be associated with a significant fall in the binding affinity of bilirubin for plasma protein and a concomitant increase in free bilirubin concentration in premature infants. Sustained release disopyramide compared to plain capsules after change-over from intravenous infusion.

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In addition, ONO-5046 and FK706 attenuated both hepatic microcirculatory dysfunction and liver injury mediated by TNFalpha and IL-1beta (10 microg/kg i.v.). In two separate scanning sessions, subjects encoded and retrieved items and their spatial context under cholinergic stimulation or placebo with the acetylcholine-esterase inhibitor physostigmine or saline being administered intravenously in a double-blind cross-over design.

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The research at admission time of ESBL-producing Enterobacteriaceae, mainly in acute geriatric wards, strict isolation precaution and hand hygiene observance, rational antibiotic usage, are the key actions to control their cross transmission. Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by a wide variety of autoantibodies, some of which are pathogenic.

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Despite high expectations of DNA vaccines as a result of promising preclinical data their clinical utility remains unproven. Accompanying the cell voltage and power density oscillations, the discrete CO concentration oscillations at the anode outlet of the PEMFC were also detected, which directly confirms the electrochemical CO oxidation taking place in the anode chamber during galvanostatic operating.

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Subsequent treatment with trypsin (0.1 microgram/ml) released 125I into the supernatant and yielded cells coated with a 33,000-dalton fragment of alpha-chain, presumably C3d. Affinity for telomeric G-quadruplex AGGG(TTAGGG)(3) binding was first screened by fluorescence titrations.

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Caudal catheters in neonates are popular, but evidence that they improve outcome is lacking. MRI may present an important diagnostic method for evaluating further treatment options in patients with remaining hormonal hypersecretion following transsphenoidal adenomectomy, particularly with regard to a second surgical approach. Whole-genome sequencing of three Spanish strains with spacer 21 missing in their spoligotype pattern revealed a series of SNPs and subsequent screening of a selection of these SNPs identified one in gene guaA that is specific to these strains.

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Effects of ochratoxin A upon early and late events in human T-cell proliferation. Hemodynamic effects of serially arranged model stenoses (tandem stenoses )

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If synergistic muscles are co-activated in the right way, sustained locomotion can occur. This article presents information to plan, implement, and evaluate a successful cross-training program. The signal intensity was measured by magnetic resonance imaging (MRI). To that end, we have engaged in a study to identify expressed sequenced tags (ESTs) from L. Stimulation of renal prostaglandin synthesis by the pressor activity of vasopressin.

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Nucleolus-organizing regions (Ag-NORs) are silver-stained loops of DNA transcribing to ribosomal RNA. A safer approach to management of the difficult airway can be achieved by improving airway management skills and adhering to universally accepted and proven airway algorithms, including developing approaches to management of predicted and unpredicted difficult airways.

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Photonic materials generated via organic chemistry have yet to surpass the native protein in terms of quantum efficiency or cyclicity. Interaction between human granulocyte collagenase and plasma protease inhibitors. The entry rate of lactic acid into the circulation as well as the rate of glycogenolysis was high in the first 4 h but decreased thereafter even though skeletal muscle glycogen stores were not exhausted. In all subjects the plasma concentration of dicoumarol in the postabsorptive phase was lower during concomitant tolbutamide treatment.

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While otosclerosis is the commonest finding in such cases, a significant number of patients have defects of the ossicular chain. Mechanisms underlying expression of Tn10 encoded tetracycline resistance.

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Although a certain percentage of low-enrolling studies can be expected in any research organization, the overall number of such studies must be managed to reduce the aggregate costs of conducting research and to maximize research opportunities. Gait rehabilitation: a new biofeedback device for monitoring and enhancing weight-bearing over the affected lower limb.

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The diagnosis of endobronchial metastasis of PSCP was confirmed by immunohistochemical staining with cancer antigen 125 (CA125), vimentin, and Wilms tumor-1 (WT-1). Expression of brush border enzymes in ethanol fed rat intestine.

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A selectionist theory of adaptive behavior dynamics instantiates the idea that behavior evolves in response to selection pressure from the environment in the form of resource acquisition or threat escape or avoidance. Activation of microglia by neuronal activity: results from a new in vitro paradigm based on neuronal-silicon interfacing technology. Data for this study came from the Office of the Medical Director (OMD), Division for Mental Retardation (DMR), Ministry of Social Affairs and Social Services. Significant preferences in the first experiment were: pine shavings over aspen shavings, corn cob over wood pellets, pine shavings over corn cob and aspen shavings over wood pellets (aspen shavings versus corn cob was not tested).

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The advantages of this new method are its expedition and the accurate and comparable results as compared to the tedious conventional technique. Fluorescence study on the conformation of a cyclic enkephalin analog in aqueous solution. Relationships between stone size and the stone-free rate, operative time, complications, hospital stay and need for re-treatment were determined.

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Knowledge of modifiable risk factors of cardiovascular diseases among patients with acute myocardial infarction. Healthcare policy makers when allocating resources should take into account the profile of elderly patients presenting to an ED and their resource utilisation.

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The recommendations focus on the management of hypertrophic scars and keloids, and are internationally applicable in a range of clinical situations. They include a thorough clinical history, standardized skin tests, reliable biological test, and sometimes drug provocation tests.

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Exacerbations are a key outcome in clinical research, providing patient-relevant information about symptomatic control, health state and disease progression. We investigated whether the aortic augmentation index (AIx), a measure of arterial wave reflection and stiffness, is associated with cardiorespiratory fitness in men without known coronary heart disease (CHD). Including lifestyle medicine in undergraduate medical curricula. However, the functions of stress-related NAC TFs remain to be elucidated in M. Data on resource use, dose escalation, and frequency of therapy were based on a nationwide field survey of rheumatologists.