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Given the safety of imatinib in humans, plans are underway for pilot clinical trials to assess its efficacy in patients with filarial infections. Increased genetic diversity as a defence against parasites is undermined by social parasites: Microdon mutabilis hoverflies infesting Formica lemani ant colonies. In eukaryotes, small amounts of nitrite confer cytoprotection against ischemia/reperfusion-related tissue damage in vivo, possibly via reduction to nitric oxide (NO) and inhibition of mitochondrial function. A recently published, uncontrolled evaluation of a Dutch clinical rehabilitation programme based partly on these methods proved to be successful.

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Groundwater quality in Scotland: major ion chemistry of the key groundwater bodies. Most pediatric oncologists are investigators, involved in clinical care as well as research. The primary purpose of this study was to investigate the effects of ET on ABP and arterial stiffness of HT recipients. It is theoretically proved that the controller can make the error converge to zero exponentially.

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Renal carcinoma 30 years after abdominal irradiation for testicular seminoma. An organized and practical approach based on an understanding of the pathophysiology and microbiology is helpful in the evaluation and treatment of these infections. The LAPW of MR patients with or without AF shows considerable SR.

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Basing his study on an extensive bibliography, the author shows that epilepsy is not a disease. Complex treatment program in malignant testicular tumors other than seminoma Numerous constrictions and notches showed the presence of lymphatic valves and were often found on the cast surface of the collecting lymphatic vessels and the side branches. Predisposing factors, symptoms, and laboratory findings associated with estrogen-induced acute pancreatitis are presented, and the mechanisms through which serum lipid elevations and subsequent pancreatitis occur are discussed.

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Three soft contact lenses of the HEMA type, discarded because of irritation of the cornea, were processed for and subsequently examined with the SEM, A large portion of the convex surface was covered with globular deposits of fungal spores. Endogenous hyperinsulinemic hypoglycemia: diagnostic strategies, predictive features of malignancy and long-term survival. Release of gentamicin sulphate from a modified commercial bone cement. Purification of human alpha-2-macroglobulin by chromatography on Cibacron Blue Sepharose.

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The varied biological functions exerted by PGE2 are through the pharmacologically distinct, G-protein coupled plasma membrane receptors termed EP receptors. Contrary to mammalian PGI, bacterial PGI was not internalized by the PGI/AMF receptor (gp78/AMF-R) and neither bacterial nor yeast PGI competed with mammalian PGI for receptor binding and internalization. The variation in reaction dynamics of OH hydrogen abstraction from glycine between HF, MP2, CCSD(T), M05-2X, BHandHLYP, and B3LYP levels was demonstrated.

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Human Hsp60 is expressed in the joints of patients with rheumatoid arthritis (RA) and can elicit a regulatory T cell response in the peripheral blood and synovial fluid. Among all three age groups, lipoprotein abnormality was observed to be more frequent in females than males.

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This article reports a study of the effectiveness of performing contact lens cultures to identify causative organisms of infectious keratitis in patients using extended-wear soft contact lenses (cosmetic or therapeutic). Limited value of two widely used enzyme immunoassays for detection of Chlamydia trachomatis in women. This study also revealed that there are at least twice as many TE-induced adaptations that remain to be identified.

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Structural elucidation of compounds 1-6 was based on spectroscopic data. Lung cancer was frequent in males over 45 years with a long history of heavy smoking. An investigation of Zr doping in NaBiTi2O6 perovskite by direct hydrothermal synthesis. By means of corrected tomography, the positions of the condyles in patients who had undergone four-premolar extraction treatment (20 edgewise and 7 Begg) were compared with the condylar positions of patients who had not yet received orthodontic treatment.

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We conducted retrospective studies of patients with clinical diagnoses of familial exudative vitreoretinopathy from June 1986 through September 2000. The tuatara is the only surviving member of the ancient Sub-Order Rhynchocephalia, and it seems likely that testosterone functions as a male sex hormone in this species, as it does in other members of the Class Reptilia. Cell cycle phase recovery from bleomycin-induced potentially lethal damage.

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Quantitative data is given to demonstrate the superior cell presentation that is achieved by this new technique for automated scanning. Recognition of gas in gallstones in routine computed tomograms of the abdomen. Hence, familiarity with the imaging presentations of various forms of CNS tuberculosis is essential in timely diagnosis, and thereby reducing the morbidity and mortality of this disease.

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Inhibitors which are analogues of fructose-6-phosphate (F6P) derived from 2,5-anhydromannitol and therefore blocked in a closed conformation, both nonphosphorylated and phosphorylated, were designed. Under normal circumstances, proinsulin conversion is largely completed before secretion, and neither the intact prohormone nor conversion intermediates are thus encountered in large quantities in the circulation. The compaction dynamics of rods is measured at three different scales: (i) the macroscopic scale through the packing fraction rho, (ii) the mesoscopic scale through both fractions of aligned grains phi(a) and ideally ordered grains phi(io), and (iii) the microscopic scale through both rotational and translational grain mobilities mu(r,t). The balance between matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) is crucial for homeostasis of ocular extracellular matrices.

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The unusual genome architecture of ciliates with separate germline and somatic nuclei in each cell, provides an ideal system to study further principles of genome evolution. Influencing clinical practice increasingly requires quality evidence to support recommendations and guidelines. Individual differences in development rate were caused by different foraging efficiency.

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Development, Optimization and Evaluation of Electrospun Nanofibers: Tool for Targeted Vaginal Delivery of Antimicrobials Against Urinary Tract Infections. We hypothesized that nebulized magnesium would confer benefit without undue risk. Bone marrow mesenchymal stem cells were isolated, purified and cultured in vitro by Percoll density gradient centrifugation combined with the cell adherence method. The TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling) technique has been described as a sensitive method for detection of apoptotic nuclei in tissues and preferential staining of apoptotic strand breaks. To explore whether acute pulmonary embolism (APE) can be quantitatively predicated early with 3 clinical scoring systems, with multidetector CT angiography (MDCTA) as the gold standard, and therefore to select a scoring system more suitable for the Chinese.

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Therefore, there is a need to educate those who work in NPS about the potential hazard of occupational exposure and the importance of using protective measures. Systematic efficacy of ivermectin MK-933 against the lone star tick. We have reported on the first case series of piperacillin-induced DRESS. In those cases where parasite culture was successful, PCR also demonstrated the rapidity with which one Leishmania species was eliminated from culture during continuous passage. Two individuals with primary progressive AOS underwent speech-language and neurologic evaluations on 2 occasions, ranging from 2.0 to 7.5 years postonset.

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Methylation of SHH promoter was evaluated using quantitative methylation-specific PCR. CR was grown on a model oil, which consisted of an inert oil matrix of pristane with n-heneicosane dissolved in it as the sole carbon source, in a stirred-tank bioreactor.

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The main orientation of the bands in both columnar systems is related to a) the representation of the vertical meridian, b) the anisotropy of the cortical magnification factor, and c) the tangential spread of intracortical connections. Outcome measures include emergency attendance and medical readmission in the past 90 days as identified from medical records, and patient-reported QOL as measured by the modified Quality-of-Life Concerns in the End of Life Questionnaire (Chinese version).

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The symptomatology of lateral space infections and the relevance of this entity to clinical dentistry are discussed. The essential sources of health-related information for India were reviewed. The potential beneficial effect of a thromboxane synthetase inhibitor, OKY-1581, on increased lung vascular permeability in experimental pulmonary microembolization in dogs. The long-lasting contractions were not inhibited by atropine, phentolamine, and propranolol. EXPERIMENTAL CONTROL OVER THE EVOLUTION OF FITNESS IN LABORATORY POPULATIONS OF DROSOPHILA PSEUDOOBSCURA.

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A rapid, sensitive, and specific gas chromatographic assay for lidocaine in plasma and blood is reported. These studies demonstrate that T cell-derived immunoregulators of host origin can be focused onto localized and disseminated malignant B cells and specifically regulate the expansion and differentiation of the neoplastic clone. Human ghrelin protects animals from renal ischemia-reperfusion injury through the vagus nerve.

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Data on first births at late maternal age, BMI trends (based on the Scottish Health Surveys) and breast screening uptake trends in the different categories were also analysed and their relation to breast cancer incidence trends explored. Techniques of microsieving, cell surface staining and measurement of cell water diffusion turnover rate have been used in this investigation to examine erythrocyte properties.

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Diagnostic pitfalls in spine surgery: masqueraders of surgical spine disease. Like the Smads, TIEGs behave as downstream effector proteins in TGFbeta-mediated pancreatic growth control. Migraine has been associated with risk of cardiovascular disease (CVD). Saccharase seems to be the main disaccharidase, and high activity of beta-glycosidase enables hydrolysis of the plant glycosides.

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Effects of stimulus frequency on the blink reflex during rest and a task. This study was undertaken to evaluate the usefulness of electrocardiographically (ECG)-gated multidetector-row computed tomography (MDCT) for the assessment of the coronary venous system and detection of its anatomical variants, in order to identify those suitable for lead placement in cardiac resynchronisation therapy (CRT).

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Sequential interactions between several adhesion molecules and their ligands regulate lymphocyte circulation and leukocyte recruitment to inflammatory foci. Although just a few years ago the dynamic behavior of a protein molecule could be simulated only in the neighborhood of the experimental conformation (or protein unfolding could be simulated at high temperature), the advent of distributed computing, new techniques such as replica-exchange MD, new approaches (based on, e.g., the stochastic difference equation), and physics-based reduced models of proteins now make it possible to study protein-folding pathways from completely unfolded structures.

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After a minimum follow up of 24 months (range, 24-36), none of the patients showed any clinical signs of lung or arm toxicity. These differences were of sufficient magnitude to call into question the feasibility, at this time, of constructing generalizations regarding PTSD utilizing only the PTSD/veteran population. Replacement with Ser resulted in the production of an enzyme, that migrates as a monomer upon non-reducing SDS-PAGE and has a lower stability compared to the dimeric wild-type enzyme.

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The internal lining of the entire male duct system is syncytial in nature, and regional variation is quite evident. This allows the cavity to be created by polymer processing, following the much more demanding semiconductor processing that is used to generate a uniform PCS. Risk factors for subclinical parenchymal lung disease have not been described. Trained panels evaluated the bitterness intensity of the cheeses at 180 and 270 days.

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Functional mapping has been a powerful tool in mapping quantitative trait loci (QTL) underlying dynamic traits of agricultural or biomedical interest. One analytical tool applied to a multitude of systems biology studies is mass spectrometry, particularly for the study of proteins and metabolites. Glycogen and the intermediate filaments are thus the principal constituents of the cytoplasm of the flat cells of the electroreceptive epidermis of Mormyrids.

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A human signet ring gastric carcinoma cell line TSGH9201 was established in vitro. Optical coherence tomography (OCT) and electrically evoked cortical potentials (EECPs) were used to determine long-term biocompatibility and functionality of the implant. The ossifying potential of the disease can apparently manifest itself early in limited areas. The patterning of cortical areas is controlled by a combination of intrinsic factors that are expressed in the cortex and external signals such as inputs from the thalamus.

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In particular, the shape of the whole muscle isometric twitch was a reliable indicator of the relative proportions of fast- and slow-twitch motor units in the muscle. Lapatinib efficacy restricted to the HPV-positive cells suggests that HPV status could be a potential marker for enhanced response to lapatinib in HNSCC.

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Neuronal activity of the cerebral cortex in cats with conditioned inhibition A control group consisted of 50 persons without any intervention. Their delivery experiences were estimated by means of interviews 3-4 days after parturition. Evidence has accumulated in rodent and primate models to indicate that the products of successful rearrangement regulate this process.

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Interaction of cholesterol-crystallization-promoting proteins with vesicles. This study aims to develop a molecular identification method for the authentication of Lodoicea maldivica seeds.

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It seems likely that logically constructed mixtures of these agents, developed from the ground up, will be necessary for the prevention of lung carcinogenesis. This finding was confirmed in two isogenic human cell lines with an engineered defect in eIF2alpha phosphorylation. The ISL-mediated autophagic and apoptotic cell death were obviously attenuated by transfection with dominant negative Atg5 (DN-Atg5(K130R)) plasmids or treatment with 3-methyladenine(3-MA).