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Platelet aggregation induced by ADP, collagen and adrenaline is increased by low concentrations of human plasma kallikrein, which does not cause aggregation by itself and inhibits the aggregation induced by arachidonic acid and Thrombofax in platelet rich plasma, and the aggregation induced by thrombin in washed platelets. Staining of immature granules of developing polymorphonuclear neutrophils by HID was intensified by the post-treatment with TCH-SP.

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Recently, this enzyme has been localized by immunofluorescence techniques on intermediate filaments and stress fibres in interphase cells and in mitotic spindles of dividing tissue culture cell lines, including the PtK1 cell line, and has been found to co-purify with spindles isolated from dividing sea urchin eggs and with muscle cell nuclei. At 30 days of healing, there were no statistically significant differences between the amount of newly formed bone in any of the groups. A comparison of the Feulgen hydrolysis curves and the chromatin compactness of the liver cell nuclei of young and old rats was made. Here we show that antithrombin antiangiogenic activity is mediated at least in part through the ability of the conformationally altered serpin to block the proangiogenic growth factors fibroblast growth factor (FGF)-2 and vascular endothelial growth factor (VEGF) from forming signaling competent ternary complexes with their protein receptors and heparan sulfate co-receptors on endothelial cells. To determine (1) reference values for cone and rod phototransduction variables derived from the a-wave of the electroretinogram, (2) their dependence on age, (3) the progression in cone and rod variables in patients with X-linked retinitis pigmentosa (XLRP), and (4) the test-retest variability in these a-wave measures compared with the variability in cone and rod b-wave measures.

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The administration of melatonin (50 ng delivered over 10 h at night) by timed infusions to pregnant, pinealectomized Djungarian hamsters for the last 4-7 days of gestation stimulated testicular weights of male pups reared in 14 h of light/day. Time-domain upconversion measurements of group-velocity dispersion in quantum cascade lasers.

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This disc fragment was placed anterolateral to the thecal sac, simulating a sequestered disc herniation. MMP-7 can serve as a prognostic indicator and a potential novel target for treatment in CRC patients. Collagen production by fibroblasts has been shown to be transformation sensitive and to correlate inversely with tumorigenicity. The identification of these novel Candida species seems to be clinically relevant because it is likely that they differ in virulence and drug resistance.

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GISANS allows for the detection of structures in the very limited sample volume of confined films as well as for a depth sensitivity to probe the near free surface part of bulk films. The infection had probably been contracted after handling wild boar carcasses from eastern Europe. This knowledge will need to be considered in the design and implementation of programmes aimed at reducing malaria transmission by suppression of An. Underreporting of semen exposure was significantly more frequent at follow-up than baseline, suggesting that the accuracy of reports of sexual behavior may vary over time. However, no data are available about the possible impact of inter-institute variability in contouring the rectum, so that the possibility of reliably using information from single-centre studies remains doubtful.

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It is therefore essential for the anaesthetist to be up to date with current clinical concepts and their impact on the conduction of anaesthesia as well as new insights into how to anaesthetise these patients safely. A similar situation applies for estrogens (E), which have been shown to induce direct effects on sperm by an extranuclear pathway. The present study compared the histopathology of the early pleural response in rats and hamsters instilled with artificial fibers. acute myocardial infarction out-of-hospital mortality in Sicilian Municipalities, with the exclusion of patients hospitalised within 15 days before the death event.

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Glucose-6-phosphatase-alpha (G6Pase-alpha or G6PC) catalyzes the hydrolysis of glucose-6-phosphate to glucose and is a key enzyme in interprandial glucose homeostasis. Purified water spray and air flow curtain of dust control has played a certain role, but the work of underground working conditions and environmental constraints, most of the dust concentration in workplace occupational exposure limits do not meet the requirements, recommended the strengthening of dust or Dust the daily management and maintenance of equipment, strengthen the ventilation, personal protection officers to strengthen operations. Two of them, NCBF1 and NCBF2, apply feature-feature correlation to remove redundant features prior to the feature selection process based on feature-class correlation. Bromodeoxyuridine differential chromatid staining technique: a new approach to examining sister chromatid exchange and cell replication kinetics. We hypothesized that the low-dimensional spatial and temporal features of muscle coordination are independent of each other.

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Principles of a universal classification of cardiomyocytes making it possible to automatically allot heart cells to individual structurally different classes are discussed. Mean value and fluctuations in a model of diffusion in porous media. Effect of delta-elemene on Hela cell lines by apoptosis induction. Effect of chlorophyll-a, fluorouracil, and pituitrin on experimental acute pancreatitis.

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A methodological survey with emphasis placed on immunoprecipitation in gels. CXCR4 homodimers were detected in tumor cells, both on the cell surface membrane and in the cytoplasm using fluorescence resonance energy transfer and photobleaching fluorescence resonance energy transfer to measure energy transfer between CXCR4-CFP and CXCR4-YFP constructs. TRC4186, a novel AGE-breaker, improves diabetic cardiomyopathy and nephropathy in Ob-ZSF1 model of type 2 diabetes.

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Synthesis and calcium antagonistic activity of a new class of 1,4-dihydropyridines having an alkoxyimino group in position 3. How can we begin to understand the mechanisms underlying various brain functions, and how can we understand what can and does go wrong in disease? Selective biochemical interaction between brain BLOC-1 and a few members of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) superfamily of proteins that control membrane fusion, including SNAP-25 and syntaxin 13, was demonstrated.

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TOTAL GASTRECTOMY AND TOTAL THORACIC ESOPHAGECTOMY IN THE TREATMENT OF BLEEDING VARICES DUE TO PORTAL HYPERTENSION The relationship between symptoms and risk factors suggests that some symptomatic individuals may have had clinically undetected cerebrovascular events and may benefit from aggressive stroke prophylaxis. This work provides new insights into the function and regulation of a novel fimbria called Gcf that is important for early establishment of a successful infection by C. In conclusion, amentoflavone has great potential to be a lead compound for the development of antifungal agents. The examination was made after a single dose of the drugs and after three-week administration.

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Different staining patterns were observed with antibodies to type I collagen. However, the p75(NTR) is also detected on cell populations that do not undergo apoptosis in response to neurotrophins. Adolescence is a time of biologic, intellectual, and psychosocial transition for young women.

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Visual-motor transformations account for three-dimensional eye position. This assay system returns results within 15 min and specifically measures iC3b while having minimal cross-reactivity to other C3 split products. Are eye movement evoked potentials different from pattern reversal evoked potentials? Advanced practice components, including case management, research utilization, collaborative consultation, and advanced educational preparation, give light to a new model of caregiver.

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Physics instruction induces changes in neural knowledge representation during successive stages of learning. We aim to determine factors associated with polyp size in different age groups. Each of these sites has been shown in prior studies to project to thalamic regions that innervate the FEF.

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The differential diagnosis of radiation myelopathy from spinal metastasis is most important because the treatment is different for each conditions. This methodology allows us to develop a spatial characterization of the reconstruction error in EIT images. Four measures of health effect were compared (quality of life, health status, days out of role, and mental well-being), using polytomous and logistic regression analyses controlling for other selected chronic conditions. Three cases of malignant histiocytosis occurring in children aged 2 months, 10 months and 14 years, are described.

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NMDA redox site modulates long-term potentiation of NMDA but not of AMPA receptors. Role of multifunctional Chemerin in obesity and preclinical diabetes. Vacuum-assisted closure devices have a wide variety of applications and have recently been used in neurosurgical cases involving complex cranial wounds. Vascular access use, pre-end-stage renal disease access timing of first nephrologist care and arteriovenous access placement, patient self-reported vascular access preferences (United States only), treatment practices as stated by medical directors. Postoperative low-frequency hearing preservation, complete loss of residual low-frequency hearing, and speech perception in quiet measures were obtained in defined intervals for both groups.

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REACTION TO PARTIAL HEPATECTOMY OF THE MOUSE LIVER EXPOSED TO THE EFFECT OF A CARCINOGENIC AMINO-AZO COMPOUND We find that the motifs contributing significantly to the specificity of binding follow the previously proposed recognition rules, distinguishing primarily between purines and pyrimidines. Lipoprotein lipase activity, LPL protein expression, and LPL messenger RNA (mRNA) expression were measured.

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A fan-out device has been fabricated using ultrafast-laser waveguide-inscription that enables each core of a multicore optical fiber (MCF) to be addressed by a single mode fiber held in a fiber V-groove array (FVA). This review gives an overview of the currently existing and most used assays for species discrimination, with a critical appraisal of the limitations of each technique. In addition, we detected a serum monoclonal peak of IgG kappa, a finding that has not been reported previously. Traditional Monte Carlo modeling of the electron beam-specimen interactions in a scanning electron microscope (SEM) produces information about electron beam penetration and output signal generation at either a single beam-landing location, or multiple landing positions.

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Twenty-three children with neuropathic bladder have been treated by intermittent catheterisation during the past 3 years. The cell suspension obtained from rat thyroid gland was cultured on temperature-responsive culture dishes, from which confluent cells detach as a cell sheet simply by reducing temperature without any enzymatic treatment. The interfacial strength of carbon nanofiber epoxy composite using single fiber pullout experiments. We report a case presenting with chronic diarrhea and cardiac manifestations who was diagnosed as having AA-amyloidosis with unknown predisposing illness based on endomyocardial, rectal and subcutaneous fat tissue biopsies. chaffeensis, improved approaches for recovery of ehrlichiae from human patients and tick hosts, and additional methods for cultivation of E.

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Longitudinal data on bone mineral density (BMD) in children and adolescents with Prader-Willi Syndrome (PWS) during long-term GH treatment are not available. Effects of obesity and obesity-induced stress on depressive symptoms in Korean elementary school children. Neither microbiological nor pharmacokinetic (PK) data alone can determine whether a drug is suitable for short-duration therapy. A meta-analysis of 8 prospective RCTs showed a higher rate of treatment failure or insufficiency with mannitol or normal saline versus HTS. Adding functional capacity through improving patient throughput.

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Bacterial cellulose-hydroxyapatite nanocomposites for bone regeneration. The EpicliCP-2003 study: A multicenter epidemiological and clinical study of lung cancer in Spain The experimental groups were exposed to excess gravity until hatching (9-12 day), whereas control groups were maintained at normal gravity.

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At room temperature complete humidification does not influence surface tension, but at 37 degrees C gamma min increases. The binding of WGA was greatly diminished after sialic acid removal. The corresponding spin relaxation time is about 100 femtoseconds.

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Acute urticaria and bronchospasm following radiographic contrast media in a dog. Podocalyxin (PC) is a polysialylated, anti-adhesin that is essential for maintaining foot process architecture and the integrity of the glomerular filtration barrier. The association among the pupil abnormalities and cognitive performances remained significant after the multiple linear regression analysis controlling for age, gender, admission coma Glasgow scale and serum glucose, presence of associated trauma, and cranial computed tomography abnormalities.

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This study aims to evaluate the cost-effectiveness of a multicomponent implementation strategy aimed at the reduction of healthcare associated infections in Dutch hospital care, by promotion of hand hygiene. The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas. All of the TG2 constructs, except the R580A mutant (which cannot bind guanine nucleotides and is therefore more prone to exhibit transamidating activity), either did not significantly affect the cell death processes or were protective. Furthermore, RA in combination with hydroquinone or 4-hydroxyanisole, or azelaic acid increases the potency of depigmenting agents for the treatment of melasma, actinic lentigines, and postinflammatory hypermelanosis. Results of this pilot intervention suggest that cycling antibiotics may be a safe and viable strategy to minimize the emergence of antibiotic resistance in intensive care units.

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Lipid peroxidation and antioxidative status in beta-thalassemia major patients with or without hepatitis C virus infection. However, this sensitive platform requires standard protocols in the preanalytical stage to avoid unwanted results caused by improper operations.

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on measuring ultrasonic scattering in blood, this phenomenon has been extensively studied both theoretically and experimentally. Errors in spin-lattice relaxation time measurements from restricted volumes.

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The level of oxidative stress in tissues is determined by an imbalance between reactive oxygen species production and antioxidant activity. First, calnexin and immunoglobulin binding protein (BiP) both associate with immature HLA class I heavy chains. Ovariectomy increases the formation of prostanoids and modulates their role in acetylcholine-induced relaxation and nitric oxide release in the rat aorta.

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Thus, proline chimeras are useful tools for a wide range of chemical and biological applications as chiral synthons or building blocks for peptidomimetic design. However, care must be taken to use the HRDP identified through the UMTT to prescribe training intensities. A very recent study, finding similarities in awake humans and anesthetized primates, has suggested that DMN activity might not simply reflect ongoing conscious mentation but rather a more general form of network dynamics typical of complex systems. Vascular endothelial growth factor-C expression in bladder transitional cell cancer and its relationship to lymph node metastasis.

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Two patients had a history of unexplained recurrent venous thrombosis and recurrent pulmonary embolism. Achievements and unsolved problems of Soviet traumatology and orthopedics

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Impact of different surgery modalities to correct class III jaw deformities on the pharyngeal airway space. Despite this need, studies on mild disruption of microalgae cells are limited. In the present study we investigated the effect of dietary fish oil on bacterial growth in vivo.

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Ozark sculpin (Cottus hypselurus), rainbow darter (Etheostoma caeruleum), Ozark madtom (Noturus albater), and banded sculpin (Cottus carolinae) were the most abundant fishes collected. Biomechanical significance of the human internal limiting lamina. The 160-kilobase genome of the bacterial endosymbiont Carsonella. All users were anaesthetists, so that experience of administration and dosage was extremely helpful.

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Prognostic value of bone marrow histology in chronic lymphocytic leukemia. These iPSC-Heps resembled human embryonic stem cell-derived hepatocyte-like cells in gene signature and hepatic markers/functions. Results of this investigation add to the growing body of research suggesting that the self-reports of alcoholics may be considered reliable particularly when obtained under standardized testing conditions. Platelet function during acetaldehyde intoxication in healthy male volunteers.

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Diurnal rhythm of response to chronic intrahypothalamic melatonin injections in the white-footed mouse, peromyscus leucopus. gonorrhoeae infection in human endocervical epithelial cells (End/E6E7 cells).

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Patients who had a minimum disease-free interval between primary tumor and liver metastasis of 12 months, no more than 3 liver lesions, no macroscopic extra-hepatic disease and in which systemic therapy showed a good response were included. We studied 366 in-patients with insulin-treated diabetes at a single UK centre.

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Mapping all TF-DNA interactions and elucidating their dynamics is a major goal to generate comprehensive models of GRNs. This mini-review introduces the emerging field of chemical proteomics and reviews recent advances in chemical proteomic technology that are offering striking new insights into the functional biology of post-translational modification. Female adult rats were divided into control, low, middle, and high dose lanthanum groups at random. There are no evidence-based published guidelines on the diagnosis and treatment of these injuries.