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To determine whether CR exerts vasoprotective effects in aging, aortas of ad libitum (AL) fed young and aged and CR-aged F344 rats were compared. This was followed by a continuous infusion of diltiazem at 10 micrograms/kg/min for 50 min. Both of the acceptance angle modifications yielded an angular response less than that of the wide-angle FT32 thermopile. They protrude from the nerve bulb above the surface of the tegument. As low back pain (LBP) patients constitute an important subgroup of chronic pain patients, we addressed the following issues: (i) to establish a simple, validated screening tool to detect neuropathic pain (NeP) components in chronic LBP patients, (ii) to determine the prevalence of neuropathic pain components in LBP in a large-scale survey, and (iii) to determine whether LBP patients with an NeP component suffer from worse, or different, co-morbidities.

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The mean values of serum thyroxine, free-thyroxine index and thyroidal 131I uptake of the patients were found decreased, compared to those of the euthyroid controls (to a statistically significant level for serum thyroxine and free-thyroxine index P less than .001). We clearly show that the inhibition of DNA repair induced by rucaparib is synthetic lethal with the DNA damage caused by 5FU in leukemic cells. A high-resolution 2D J-resolved NMR detection technique for metabolite analyses of biological samples. In this study, eight single-chain antibodies (scFv) and one single-chain T-cell receptor (scTCR) were secreted as fusions to GFP using a Saccharomyces cerevisiae expression system. The goal was to assess the impact of influenza vaccine clinical alerts on missed opportunities for vaccination and on overall influenza immunization rates for children and adolescents with asthma.

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Multiple processes bear on perceived stigma among people with chronic health conditions. A 75-year old female presented at the emergency room with progressive dizziness, headache and vomiting, where a brain CT and MRI showed a posterior cerebellar tumor. Anticoagulant therapy appears to be effective and safe in the treatment of this postoperative complication. We found huge differences between primary and secondary lymphedema for the thigh. Adenocarcinomas of the oral cavity: a clinicopathologic study of terminal duct carcinomas.

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Cephalometric analysis was also performed to determine the amount of proximal segment rotation. Non-exponential behavior of the nuclear magnetization in H-doped copper oxides. Assessment of profilin as an allergen for latex-sensitized patients. Pathological features, including PNI, were re-reviewed under regular hematoxylin-eosin staining in 190 patients with T1-2 oral tongue SCC. Here, we review the pathogenesis and molecular aspects of PRTH, present a single case with inappropriate TSH secretion suffering from thyrotoxicosis treated with PTU, and discuss the possible choice of therapeutic options to correct the imbalance of thyroid hormone responsivity in both the hypothalamus-pituitary and peripheral tissues.

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Effects of fasting at different stages of lighting regimen on the proliferation of jejunal epithelial cells during rat pup weaning. The protective effect of testosterone on myocardial ischaemia is maintained throughout treatment without decrement. This study examines retinal thickness above drusen relative to drusen-free areas in the same patient and a normal population.

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Interaction of MccE492 with target cells leads to the depolarization and permeabilization of their inner membranes. Evaluation of the biocompatibility of dialyzers by leukocyte kinetics and the dynamics of the blood acid-base balance Influence of temperature on the velocity and on the isotope profile of slowly transported labeled proteins. High-dose autologous stem cell administration in malignant diseases--an established method, unclear indications

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Interactions of melatonin and its metabolites with the ABTS cation radical: extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones. Peripheral corticosterone levels were not significantly affected, although there was a strong tendency towards an increase. L-lactic acid specific interaction with the lightest subunits was not inhibited by removal of the divalent cations. The energy barrier for switching between two states was obtained from the conformational distribution based on a Boltzmann probability function and closely follows a predictive mechanical model.

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Questions about employment as a bus driver, other jobs, and residence were asked. To evaluate the clinical efficacy of an established programme of occupational therapy in maintaining functional activity and reducing further health risks from inactivity in care home residents living with stroke sequelae. Isolation and characterization of a slow-migrating class of adenovirus type 2 hexons.

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Effect of 1-methyladenine on localization of Galpha1-protein in starfish oocytes For the inexperienced interpreter of chest radiographs, the normal scapula can mimic some very common and potentially serious abnormalities. Moreover, serum levels for allergen specific IgG4 also increased over the course of treatment. Usefulness of BNP measurement for stratifying cardiovascular risk in hypertensive patients Basal cortisol and DHEA levels in women with borderline personality disorder.

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Expanding a performance improvement initiative in critical care from hospital to system. Absorbed dose distribution measurements in brachytherapy using ferrous sulphate gel and magnetic resonance imaging.

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In all these cases, quantitative model selection criteria such as the Akaike and the Schwartz Bayesian information criteria indicated the superiority of the bilinear model compared to adequate less parametrized alternatives such as linear, parabolic, exponential, or classical growth (e.g., logistic, Gompertz, Weibull, and Richards) models. Communication difficulties are common in cerebral palsy (CP) and are frequently associated with motor, intellectual and sensory impairments. Ultrathin sections are more cleanly and uniformly stained in bulk by the use of these staining boxes than they are when stained individually by a standard method.

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Mice fed cycad seed flour containing the isolated sterol glucosides show behavioral and neuropathological outcomes, including increased TdT-mediated biotin-dUTP nick-end labelling (TUNEL) positivity in various CNS regions. A histological diagnosis was available in 374 (110 males and 264 females) out of 7,809 thyroid aspirates examined at Mubarak Al-Kabeer Hospital, Kuwait, from 2004 to 2012. The results support the assertion that internalization of sociocultural pressures mediate the adverse effects of the thin ideal. This is the first description of a case of recurrent meningitis with C3 and CH50 deficiency in a Turkish family.

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The condition can be confirmed when the injection of local anesthetics in the trigger point(s) relieves the pain. Subacute sclerosing panencephalitis (SSPE) is a slowly progressing fatal human disease of the central nervous system (CNS) that is associated with measles virus persistence. Vitamin D3 analogues that contain modified A- and seco-B-rings as hedgehog pathway inhibitors.

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Magnesium-deficiency does not alter calcineurin inhibitors activity in mice. Ovariotomy for menstrual madness and premenstrual syndrome--19th century history and lessons for current practice.

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In the first experimental series 10 animals were given propranolol subcutaneously (3 mg/kg body weight). Treatment of the sedimented fraction with 6 M urea solubilized all of the proteins except the 39-kDa protein. ThinPrep liquid-based cervical cytology: a retrospective analysis of 50,340 cases

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All hospitals had empirical antimicrobial prescribing guidelines, and all 10 hospitals with haematology and oncology services had febrile neutropenia guidelines. Recently, links between cAMP, phosphatidylinositol 3-kinase (PI3K) and protein kinase B (PKB) signaling pathways in thyroid and granulosa cells have been observed. We have introduced point mutations, insertions and deletions into all of the different coding and non-coding regions of the CRPV genome and have tested their infectivity in this model. Partial replacement of waxy cornstarch by recrystallized amylose retards the development of insulin resistance in rats. Particularly in the event of bioterrorism, the caregivers are typically able to intervene much later than the toxic exposures.

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Further study of the utility and safety of this needle in humans is warranted. The use of a self-reporting pain assessment tool as a communication instrument provides an effective foundation for evaluating pain intensity in cancer pain management. Reorganization in hematology: the objectives and ways of improving hematological services for the population

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Upon aging, the degradation of the nucleotides causes a cubic-to-hexagonal phase transition. Estradiol-17 beta had a weak inhibitory effect on GABA responses of nerve terminals, but only at high concentrations. The present study supports the concept of widespread cortical and subcortical deficits in schizophrenia.

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Diagnosis of a major depressive episode by the Diagnostic and Statistical Manual of Mental Disorders of the American Psychiatric Association requires 5 out of 9 symptoms to be present. Some of them appear to be associated with genetic recombination events. risticii was not detected from the plasma samples obtained from these horses. Clear cell renal cell carcinoma (ccRCC) is the most common malignancy of the adult kidney and displays heterogeneity in clinical outcomes. Although many seizure-induced mechanisms have been postulated, or even demonstrated, that can give rise to persistent neuronal disturbances, including neuronal death, they are only of clinical concern if they result in interictal neurological or cognitive dysfunction, developmental delay, or progressive epileptogenesis that makes seizures worse.

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Familial transmission and minimal sequence variability of human T-lymphotropic virus type I (HTLV-I) in Zaire. This is a patient with septicaemia and diabetic ketoacidosis who developed an acute ischaemic lower limb from an arterial thrombus. We present an alternative treatment employing a hybrid approach used in 3 patients with congenital heart disease. Cortical mechanisms of normal and abnormal processes in the visual system, Part 2.

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The electronic properties of Ti-MoS2 top contacts can be tuned by intrinsic vacancies in monolayer MoS2. Comparative sequence analysis allowed us to identify a branch of homologous dehydrogenases that bear a similar metal-binding motif. A prospective, longitudinal, descriptive study of the effect of a customized wheelchair cushion on clinical variables, satisfaction, and functionality among patients with spinal cord injury. Strain PF1 is a potent plant-growth promoter, useful for diesel fuel phytoremediation applications.

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The daily use of an effective antiplaque/antigingivitis antimicrobial mouthrinse is well-supported by a scientific rationale and can be a valuable component of oral hygiene regimens. Both neonates had evidence of pulmonary hypoplasia but survived. This is the first report on the decrease in PHA-stimulated proliferation ratio (stimulability) and RNA level in PBMC of DS patients in relation to age. Women can be less fatigable than men because of sex-related differences within the neuromuscular system that impact physiological adjustments during a fatiguing task. Genetic transformation with conventional breeding is certainly a more promising tool for incorporation of agronomically important genes that could improve existing Hevea genotype.

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Autoimmune pancreatitis (AIP) sometimes mimics pancreatic cancer, and is rarely resected under this misdiagnosis. This is a descriptive, cross-sectional study of 200 patients with a singleton gestation, who underwent a fetal anatomy survey between 18 to 23 weeks of gestation, with documented umbilical cord morphological patterns and blood flow characteristics. Thirty patients with early onset chronic depression were compared with 30 patients with episodic depression and 30 healthy, never-depressed controls in terms of self-reported cognitive-behavioral (social and non-social) and emotional avoidance. Recent studies have put forward that although elevated CRP is a risk factor for cardiovascular disease, it is not helpful in the prediction of cardiovascular disease risk.

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In some cases, data on chronic or prenatal NMDA receptor antagonist exposure have been introduced for comparison. The laboratory indices were examined including fasting serum glucose (FSG), fasting serum insulin (FSI), insulin sensitivity index (ISI), and morphological changes of pancreas, and levels of insulin receptor (InsR), insulin receptor substrate (IRS1/2) and glucose transporter (GLUT2) mRNA expression in pancreas tissue were determined by the reverse transcriptase polymerase chain reaction (RT-PCR). 15 derivatives among those showed repeated activity against the sarcoma growth. Detection of a nuclear, EBNA-type antigen in apparently EBNA-negative Herpesvirus papio (HVP)-transformed lymphoid lines by the acid-fixed nuclear binding technique. Matching theory and the evolutionary theory make conflicting predictions about the outcome of this critical experiment, such that the results must disconfirm at least one of the theories.

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Although the posterior of the eye can be reached by intravitreal injections and implants, AMD is a chronic disease process that is likely to require prolonged or indefinite exposure to antiproliferative agents. The tumor in each compartment consisted of a huge lymph node conglomerate respectively displacing the submandibular gland. Use of the second dorsal metacarpal artery-based bilobed island flap for thumb reconstruction. Models of systemic drug absorption after oral administration are frequently based on a direct or a delayed first-order rate process. In corpus luteum the lowest expression was observed during days 10-12 of the cycle, whereas markedly higher levels were detected in late-luteal stage and gestation.