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Previously, we have shown a significant antitumour effect in bladder cancer xenografts in a nude mouse model using intratumoural herpes simple virus thymidine (HSV-TK) and Endostatin gene therapy. Existence of a peripheral nerve mechanism of interoceptive effects on the function of the adrenal medulla

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The effect of mild hypoxia on the ionic currents in cardiac muscle. A DTaP-IPV//PRP-T combination vaccine (Pentacel) has been universally used in Canada to provide immunization against diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae type b with single injections at 2, 4, 6 and 18 months of age. Effects of supplementing concentrates differing in carbohydrate composition in veal calf diets: I. Implementation strategies can vary from a complete vendor solution providing all components (hardware, software, support), to a strategy similar to our own where standard computer and networking hardware are used with specialized software for management of image and measurement information. AlloDerm and Tutoplast fascia lata retained architecture closer to that of untreated tissue than did DuraDerm and cadaveric fascia lata, respectively.

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The scheme has an important feature in that it is simple and transparent in design and in the corporation of performance and robust stability issues. In the present case, the patient was successfully treated via adjuvant antibiotics and transrectal ultrasonography (TRUS)-guided prostate needle aspiration. The selection of the appropriate type of longitudinal design requires selecting the option that best addresses the theoretical questions asked about developmental process and the use of appropriate statistical procedures to best exploit data derived from theory-predicated longitudinal research.

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This has revealed that ITs only initiate 10 to 20 h after the completion of RH curling, by which time major modifications have occurred within the so-called infection chamber, the site of bacterial entrapment. The relationship between chronic prostatitis and fertility has been disputed for many years.

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Diverging viscosity and soft granular rheology in non-Brownian suspensions. Effects of manganese oxide on monkeys as revealed by a combined neurochemical, histological and neurophysiological evaluation. Several case reports have described this complication, but the actual incidence is unknown and likely underreported. The oxidative stress appears to result from iNOS upregulation in the photoreceptor mitochondria and cytokine generation in the retina by a few antigen specific infiltrating T cells. Despite of the low incidence of neonatal appendicitis, it should be taken into consideration if unclear abdominal symptoms occur in the neonatal period.

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There is no non-invasive method to determine the individual optimum of maximum exercise heart rate. Determinant selection and macrophage function in genetic control of the immune response. Recent advances in the fields of molecular biology and genetics, along with intracardiac mapping techniques, have led to a greater understanding of the underlying mechanisms of and therapeutic options for these syndromes. A small capsulorhexis diameter, its central localization and regular shape result in less PCO following phacoemulsification. The results showed that bulk Min-U-Sil 5 and SRM 1878a calibrations were identical and accurately estimated the respirable quartz fraction.

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Further, the same network is activated during the observation or imagination of these movements. We report on the recruitment and randomization, design, and conduct of an ongoing randomized controlled trial of one hundred and six patients with borderline personality disorder. Embryotoxic effects of phtalic acid derivatives, phosphates and aromatic oils used in the manufacturing of rubber on three day chicken embryos. These include covalent linkage of activated TNP groups from the soluble proteins to cell surface components, macrophage processing of the soluble conjugates and presentation to the responding lymphocytes in association with H-2-coded self structures, or hydrophobic interaction of the TNP-proteins to cell surfaces. Macrophage Colony Stimulating Factor and Monocyte Chemoattractant Protein are elevated in sera of intrinsic asthmatics compared to normal controls.

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The analysis of case histories disclosed that peptic ulceration, recurrent epistaxis and multiple pregnancies could account for iron loss in seven patients. An overview of progress in utilization of educational technology for educating the hearing impaired. After coronary sclerosis, aortic dissection represents an important differential diagnosis in the evaluation of acute thoracic pain. Nevertheless, recovery was more apparent in the animals exposed to alternating current than in those exposed to direct current. Cytotoxicity of the venom from the nematocysts of jellyfish Cyanea nozakii Kishinouye.

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We report the mobilization by cointegration of the gonococcal 5.2 kb beta-lactamase plasmid pSJ5.2 in an Escherichia coli background. Evidence is accumulating that electroencephalographic (EEG) sleep slow wave activity (SWA), the key characteristic of deep sleep, is regulated not only globally, but also locally.

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Degenerate oligonucleotide primers were designed according to conserved amino acid regions of known cysteine proteinases. We show that North Atlantic gyre surface salinities oscillated rapidly between saltier stadial conditions and fresher interstadials, covarying with inferred shifts in the Tropical Atlantic hydrologic cycle and North Atlantic overturning circulation. TARP directly associated with actin, and this interaction promoted actin nucleation as determined by in vitro polymerization assays. In order to test this hypothesis, in the current paper we tested the activation of two kinases, Akt/PKB (protein kinase B) and Erk (extracellular signal-regulated kinase) and their substrates in 10 sporadic medulloblastoma cases.

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However, outcomes of DCD kidneys in pediatric recipients remain unclear, primarily because of limited sample sizes. In patients with first-episode schizophrenia, we examined whether emotion perception is associated with disruptions to high-frequency (40 Hz) gamma synchrony and whether these disruptions predict self-regulatory adaptive compensations reflected in social cognitive behaviours.

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Osteogenic potentials of dura mater cultured in vivo in diffusion chambers the isosorbide dinitrate is associated with lower duration of labor compared with dinoprostone.

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Signs of local toxicity with this combination were also looked for. Subchorionic hematoma as a complication of anticoagulation therapy is rarely reported. To evaluate the oesophageal motor activity preceding episodes of reflux, 10 pathological and 10 non-pathological refluxers and 26 normal subjects were investigated.

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Effects of testosterone on neuromuscular transmission in rat isolated urinary bladder. Only one tool, the Primary Care Assessment Tool (PCAT), scored highly on primary care features, as it was designed to assess both structural and process features of primary care and is available in multiple user formats. Effects of refractive index mismatch in optical CT imaging of polymer gel dosimeters.

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Three pairs of primers were mixed in the same reaction and the PCR amplification products were analyzed by PAGE and silver staining. Discriminating qualitatively at the sub-micrometer level the lateral distribution of constituent elements, and correlating it to the sub-cellular biological structure, continues to be a challenge. We investigated the effect of fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, on insulin sensitivity including lipid metabolism in skeletal muscle. Inhibition of either GATA5 expression or NF-ATc activation, blocks terminal differentiation at a pre-endocardial stage and GATA5 and NF-ATc synergistically activate endocardial transcription.

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Various methods have been developed to detect minimal residual disease (MRD) after transplantation to identify patients at risk for relapse. Effective vaccines are needed for these and other avian influenza viruses.

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To study functional neurologic and cognitive outcome and health-related quality of life (HRQoL) in a cohort of patients included in a randomised controlled trial on glucose control following out-of-hospital cardiac arrest (OHCA) from ventricular fibrillation (VF) treated with therapeutic hypothermia. We first detected a definite nitrosyl hemoglobin (HbNO) signal in the jugular blood by electron spin resonance spectroscopy during early reperfusion after cerebral ischemia.

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TopBP1 knockdown increased, while over-expression decreased transient virus replication, without affecting cell cycle. It was found that no direct online measurement principle for hairy root biomass in submerged and solid-state culturing environment is available.

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The submental flap: Technical adaptions and clinical application. Spastic syndrome and vitamin B supply in children with toxic pneumonia in the 1st year of life A disruption in normal sleep may be associated with increased irritability and aggression. Comparison of specific absorbed fractions (SAF) in the Brazilian adult male and the reference man phantoms.

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Atropisomeric myristinins: selective COX-2 inhibitors and antifungal agents from Myristica cinnamomea. Distinct patterns of flow distribution occur in the muscles during exercise that are related to the fiber-type composition of the muscles or muscle parts (and, presumably, the patterns of fiber recruitment) and the intensity of the exercise. The tigecycline susceptibility determinations were performed with E/test. Understanding pediatric chronic pancreatitis: inspiration and hard work required.

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Bazedoxifene was associated with a favorable endometrial, ovarian, and breast safety profile in postmenopausal women with osteoporosis. Concise review: Deciphering the mechanism behind induced pluripotent stem cell generation. The version developed showed sufficient validity and reliability and could be considered as a suitable instrument to assess risks of elder abuse in a Spanish-speaking context.

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Catalytic properties of the synthetic polypeptides were studied in hydrolysis of p-NFA, Z-L-Ala-ONp, and Z-D-Ala-ONp. Two groups of 3 rabbits each were immunized with either recombinant vaccinia virus, WR-SFB5env, carrying the human T-cell lymphotropic virus type I (HTLV-I) env gene at the site of the hemagglutinin gene of the WR strain, or control vaccinia virus, HA-WR, lacking the functional hemagglutinin gene. Surgical removal of cavernous tumors is indicated only for tumors extending outside the CS. Imidazole was found to be a rather potent contracting agent, while oxymetazoline only caused weak contractions.

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The optical design includes a square lenslet array positioned with its diagonals aligned with the most typical principal astigmatic meridians of the eye. The USP/NF provides requirements for sampling plans, testing procedures, and acceptance criteria for these tests. The free secondary bile acids, deoxycholate and lithocholate, corresponding respectively to cholate and chenodeoxycholate, are extremely toxic, the latter more than the former.

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The E28D variant of dihydrofolate reductase from Moritella profunda was generated and found to have the same K (i) (within error) for the competitive inhibitor trimethoprim as the wild type enzyme. Classification of the enteric nerve cells of the porcine small intestine into two subpopulations using enzyme histochemical techniques. Several experiments showed that hydrolysis of 4-nitrophenyl acetate was not catalysed by contaminating esterase activity. In a two-year study of mothers of children with congenital central-nervous-system defects and their matched-pair controls, exposure to noxious influences during pregnancy was analysed.

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We studied the renal effects of two statins in patients with diabetes who had proteinuria. The results showed that NPC1 protein was expressed in oligodendrocytes and the amount of myelin protein was generally decreased in all parts of the brain and spinal cord in NPC1-mutant mice. The hypothesis of a monogenic inheritance of dark longitudinal bands on the shell in the gastropods Littorina obtusata and L. With respect to the H-2 haplotype of the mice, both intact and implanted thyroid glands of CBA/J (H-2k) and C3H/He (H-2k) mice showed severe thyroiditis, whereas those of BALB/c (H-2d) and C57BL/6 (H-2b) mice developed mild inflammation.

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Millisecond dynamics in the allosteric enzyme imidazole glycerol phosphate synthase (IGPS) from Thermotoga maritima. For this aim, an experimental setup is designed to independently control both processes in hemoglobin and intralipid solutions. Respondent-driven Sampling (RDS) is a new form of chain-referral sampling, which is superior to random sampling and traditional non-probability sampling in hard-to-reach populations.

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New understanding will emerge through integration of the analytical approach of molecular-genetic manipulation and the systemic approach of model simulation. Plotted A-line graphs reveal a distinctive morphology and a greater than two orders of magnitude increase in signal amplitude subsequent to converting FITC elastin into submicrospheres (despite a four orders of magnitude decrease in concentration).

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This study provides valuable and new information on the metabolism of DIS, which will be helpful for further understanding its mechanism of action. Additional biologically relevant factors that contribute to IgH regulation remain to be identified and incorporated into a mechanistic model for regulation. The global results are on the same levels as observed in other studies, but the values obtained in 3 of 4 parishes are relatively high.

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Obesity has been associated with poor clinical outcomes in critically ill children. Biological nitrogen removal with nitrification and denitrification via nitrite pathway. An emerging paradigm in innate immune signalling is that cell biological context can influence the outcome of a ligand-receptor interaction. Three groups of 5 male rats were treated with CCl(4) for 0 (control), 5 or 10 weeks, to induce liver fibrosis and cirrhosis.

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Cowpox virus infection in pet rat owners: not always immediately recognized. Rational speed of distraction in pathologically restructured bones in pseudarthroses (experimental study) A novel biomechanical device improves gait pattern in patient with chronic nonspecific low back pain. We propose that the ATR-Chk1-PP2A regulatory circuit functions to keep Chk1 in a low-activity state during an unperturbed cell division cycle but at the same time keeps Chk1 primed to respond rapidly in the event that cells encounter genotoxic stress.

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Gene transfer of neuronal nitric oxide synthase to the paraventricular nucleus reduces the enhanced glutamatergic tone in rats with chronic heart failure. Associations of energy, fat, calcium, and vitamin D with prostate cancer risk. Although genetic factors are important, atypical prenatal maternal immune responses may also be linked to the pathogenesis of autism. The objective of the present retrospective study was to review the clinical and histopathological presentation of this neoplasm in children. Therefore, the aim of this study was to identify correlations between common SNPs in miR-27a, miR-146a, and miR-124a with T2DM among a Chinese population, as well as to explore diabetic pathological mechanisms and the impact of environmental factors.