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The purpose of this study is to evaluate the efficacy and tolerability of carboplatin, pemetrexed and to assess differential outcomes in patients with oropharyngeal primary and HPV related disease. It differs from the contingent negative variation in that it can occur in the absence of attention or during sleep. In this article, we review current approaches to episode of care development and reimbursement. Pressure-induced superconductivity in beta- Na (0.33) V(2)O(5) beyond charge ordering. Use of hepatocyte cultures for preliminary metabolism and cytotoxicity studies of a new anti-hypertensive agent, oxaminozoline.

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Elevated plasma GABA levels were found in youngsters with Autistic Disorder. To determine why emergency department (ED) patients leave without being seen (LWBS) by a physician and to ascertain whether they receive alternative medical care.

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The role of lipocortin 1 (LC1) in the steroid feedback control of hypothalamo-pituitary-adrenocortical function. Safety, identity and consent: a limited defense of reproductive human cloning. All patients treated with endovascular stent grafts for thoracic type B dissections at 5 major Vascular Centers in Sweden were identified through local databases. Overall, there is an urgent need for better monitoring and control of food-borne parasites using new technologies. Usefulness of saline pushing in reduction of contrast material dose in abdominal CT: evaluation of time-density curve for the aorta, portal vein and liver.

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Interstitial irradiation for recurrent leiomyosarcoma in the vagina using the template technique Here, we show that COUP-TFI is required for proper axonal growth and guidance of all major forebrain commissures. The simulated thermally weighted photoabsorption spectrum of Au(-)(7) is dominated by planar structures, and it agrees well with the measured one.

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Chondrocyte-ECM (extracellular matrix) interactions are believed to play a pivotal role in the development and metabolic homeostasis of articular cartilage. Sphingosylphosphorylcholine induces stress fiber formation via activation of Fyn-RhoA-ROCK signaling pathway in fibroblasts. In the chronical ill and under different hormonal contraceptives these two processes are overlapped disturbing a unique negative or positive correlation of heparinocytes and FDP. The DVD could be appropriate for use in supporting people with HD to engage in exercise at home, either outside of therapy sessions or upon completion of a therapy program.

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We show that only duplicates that arose through post-multicellularity duplication events show a tendency to become more specifically expressed, whereas such a tendency is not observed for duplicates that arose in a unicellular ancestor. The synthesis of vitamin D derivatives and analogues, more especially that of 25-hydroxyvitamin D, 1, 25-dihydroxyvitamin D et l alpha-hydroxyvitamin D has opened a new field of investigation in pediatric pharmacology.

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The reticular cells possessed numerous free ribosomes and polysomes, well-developed Golgi apparatuses, dilated rough-surfaced endoplasmic reticula, and many coated vesicles. Inflammatory eye reactions (IERs) are rare but have been associated with medications to treat osteoporosis. Using conventional microelectrode techniques for the intracellular recordings of the membrane potential, the effects of labetalol were studied on cardiac Purkinje, atrial and ventricular muscle fibres of the dog. A detailed molecular characterization, necessary to define the mechanism of their formation, has so far been lacking. The sister developed angle-closure glaucoma, which was refractory to medical and laser therapy.

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The significance of these findings with regard to the proposed contribution of small-vessel platelet sequestration in the pathogenesis of late complications of diabetes mellitus is discussed. The ability to use an effective treatment constitutes a main concern in the management of acute ischemic stroke. Use of a locked volar plate predictably leads to better patient-reported outcomes (DASH scores) in the first three months after fixation.

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We designed a multi-center, prospective, randomized, open label, blinded-endpoint trial, ADVANCED-J, to compare the increases in dose of A II antagonist and the concomitant use of a Ca-channel blocker (amlodipine) and A II antagonist in hypertensive patients with diabetes mellitus, whose blood pressure levels were inadequately controlled with A II antagonist. A large amount of gold granulae were found in the inclusion bodies and the virions were seen occasionally. Highly sensitive quantification of pyrethroid insecticide etofenprox in vegetables with high-performance liquid chromatography and fluorescence detection. The not so universal tree of life or the place of viruses in the living world.

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The percentage of inhibition of DNA synthesis was minimum at 4 hr and maximum at 19 hr after drug exposure. Effect of hemagglutinin-neuraminidase inhibitors BCX 2798 and BCX 2855 on growth and pathogenicity of Sendai/human parainfluenza type 3 chimera virus in mice. It developed gradually in the left lateral thigh, which had been bruised 8 months before, but had produced no mass-related symptoms initially. These efflux transporters are responsible not only for export of compounds involved in pathogenesis such as secondary metabolites, but also export of host-derived antimicrobial compounds.

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Optimal treatment of leptomeningeal spread in glioblastoma: analysis of risk factors and outcome. Furthermore, we found that IL-13Ralpha2 became associated with IL-4Ralpha in the presence of IL-4.

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The developed E2 ELISA test was capable of detecting MG antibodies in the sera examined. Sonographic assessment of interstitial lung disease in patients with rheumatoid arthritis, systemic sclerosis and systemic lupus erythematosus. Correlations in brain activity between two areas (functional connectivity) have been shown to relate to their underlying structural connections. The effects of either metoprolol or ivabradine were assessed 15 min after experimental occlusion of a coronary artery (CAO), 28 days after CAO (drug gavage), and in vitro hearts (Langendorff apparatus).

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Myopic power was found to be positively correlated with the depression in the lower papillo-macular area in both NTG and POAG eyes, and it was negatively correlated with the depression in an upper arcuate area extending just nasal to the fixation only in NTG eyes. Although NAIT is transient, during its active phase thrombocytopenia can cause intracranial hemorrhage with grave neurological sequelae or death. Delayed clearance of all-trans-retinal causes accumulation of its condensation products, A2E, and all-trans-retinal dimer (RALdi), both associated with human macular degeneration. Chlamydiae, bacterial obligate intracellular pathogens, are the etiologic agents of several human diseases. The prenatal origin of population differences in the crural index indicates a genetic determination of these differences whereas limb length and relative epiphyseal width likely are both genetically and environmentally determined.

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The 40-item Readiness Estimate and Deployability Index Revised for Air Force Nurses Short Form provides evidence of reliability and validity as a self-assessment measure of deployment preparedness. To evaluate the effect of silicone oil (SO) on the corneal endothelium in SO filled phakic and pseudophakic vitrectomizied eyes.

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An unusual case of acute muscular atrophy in a patient with a severe exacerbation of asthma requiring mechanical ventilation is reported. Adenosine is involved in the regulation of different metabolic processes under physiological and pathologic conditions. Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity. These patients can have uncomplicated pregnancies and spontaneous vaginal deliveries.

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Antisera against purified mouse liver cell membranes were surface membrane but not organ-specific. Peripheral blood mononuclear cells as a source to detect markers of homeostatic alterations caused by the intake of diets with an unbalanced macronutrient composition. Advice on dealing with febrile convulsions to be given at the routine health examination of infants--clinical description of the condition and the emergency treatment given by mothers TURP and low-energy TUMT treatment in men with LUTS suggestive of bladder outlet obstruction selected by means of pressure-flow studies: 8-year follow-up. Survey on the timeliness and prognostic value of the decision to hospitalize in suspected acute myocardial infarct

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The second one is about significance of the degenerative findings which are observed in the discs of young subjects. Changes in the number, composition and settlement-structure of the Hungarians in Slovakia. This study show that VDR ligands exerted different effects on OSTalpha-OSTbeta in the rat and human intestine and liver compared with other nuclear receptors, FXR, PXR, and GR, pointing to species- and organ-specific differences in the regulation of OSTalpha-OSTbeta genes. Both Akt2 and Akt1 associated in complexes with Pak1, but only Akt2 inhibited Pak1 in kinase assays, suggesting an underlying molecular basis for the different cellular phenotypes.

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The data were correlated with the results of fundoscopic examination carried out on the same infants within the subsequent 24 h. Synthesis of the stereodefined (24R)- and (24S)-(22E)-24-isopropenyl-22-dehydrocholesterols (1a, 1b) followed by (1)H- and (13)C-NMR data comparison of these sterols established the (24R)-configuration of 1. Factors other than mutations in the CFTR gene can produce phenotypes clinically indistinguishable from nonclassic cystic fibrosis caused by CFTR dysfunction.

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The article reports on a case of involvement of the stomach, duodenum, terminal ileum, colon and rectum within the overall pattern of a lymphocytotic well-differentiated malignant lymphoma. With large defects, however, only the tubular repairs were effective in restoring neural continuity. If results from patients with known resistance patterns that vary from normal are included, the overall susceptibility value for the institution could be misleadingly skewed.

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Information was collected using a pre-designed questionnaire administered through interviews. Deviations from the normal of alpha-fetoprotein (AFP) concentrations in fetal serum, amniotic fluid, maternal serum and adult human serum can be explained by understanding the normal physiology and the pathophysiology of AFP synthesis and metabolism. To determine the incidence of and predisposing risk factors for lactic acidosis in HIV-infected patients on antiretroviral drugs in South Africa.

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To aid in the development of three-dimensional models of membrane-bound proteins, a consensus procedure for predicting alpha-helical transmembrane segments from amino acid sequence is presented. faster healing, and elimination of disadvantages involved in using barrier membranes.

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Several investigations have suggested that disruption of circadian rhythms may provide the foundation for the development of mood disorders such as bipolar disorder (BP) and major depressive disorder (MDD). removal of endotoxin from the blood stream could not be evaluated in this study, presumably due to the small number of patients and the relatively short perfusion times.

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strain ERG5 was isolated from a bacterial community, originating from a groundwater aquifer polluted with low pesticide concentrations. The incidence rates and the mean age at disease onset were compared with those from 1980, 1985, 1990, and 1995. These findings have implications for understanding the link between natriuretic peptide activity and cardiovascular risk. Nevertheless, qualitative content analysis revealed the following themes: integration, autonomy, confidence, authority, and advocacy consistent with a perceived enhanced competence in the nursing role.

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Surgery is not required for most men with prostatic hypertrophy. Quantitative histochemical study of changes with age in intracellular lipids of xiphisternal cartilage in rat and rabbit.

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The wild-type cells acquired freezing tolerance in response to cold acclimation treatment, but very little increase in freezing tolerance was observed in the ABA-insensitive lines. Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation. The human melanoma A375 and 518A2 cell lines were exposed to various statins in a time-dependent and dose-dependent manner, and indicators of apoptosis, caspase activity and individual apoptotic pathways were analysed for 3-hydroxy-3-methylglutaryl-coenzyme A reductase dependent and independent effects.

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The main characteristics in this type of tumors, the importance of performing CT scan and histopathological studies in the diagnosis and treatment are emphasized. Thirty-seven women with CC-resistant PCOS were randomly assigned to be pretreated with 500 mg of metformin or placebo 3 times per day for 2 cycles, and 100 mg of CC was given on days 5 through 9 of the second cycle in both groups. With this study we wanted to evaluate the efficacy of this new method in patients with low back pain. Chest radiography and CT imaging showed a left superior mediastinal tumor.

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As a result of the observations made with the light and electron microscopes, it is concluded that the ectopic cortex may contain functional cells in spite of the abnormal location of the tissue. Clinicians should be aware of the high occurrence of alexithymic traits among BMS subjects as such traits may affect the doctor-patient relationship.

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Minimum serum concentrations of DNG increased only slightly during phases of the regimen during which DNG was administered. The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines. We observed self-rated anxiety, depression, and craving during alcohol withdrawal and assessed beta E levels (RIA) in a consecutive sample of 60 alcoholics on day 1 and day 14 after onset of withdrawal, and in 30 healthy volunteers. On the other hand, the time of grooming in the open-field test was decreased in zinc-deficient rats.

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The inclusion of acupuncture and biodynamic correction in the complex therapy of patients with chronic vertebrobasilar insufficiency increases the effectiveness of integrated treatment compared with conventional therapy that was confirmed by neuropsychological studies of patients with discirculatory encephalopathy caused by vertebral pathology. The changes were interpreted to indicate cerebral dysfunction, probably conduction block in intracerebral axons.

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The structural compatibility of two hyperthermostable family 1 glycoside hydrolases, Pyrococcus furiosus CelB and Sulfolobus solfataricus LacS, as well as their kinetic potential were studied by construction of a library of 2048 hybrid beta-glycosidases using DNA family shuffling. In the period 1991-1996, during the war in Croatia and Bosnia, six patients with rectourethral fistulas caused by war injuries were operated in our institution by the same surgeon.

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AdsecV elicited specific T cell responses and high IgG titers in serum within 2 weeks after a single intramuscular immunization. The ratios serum/left ventricular tissue in dogs, serum/right auricular appendage in dogs, serum/whole heart tissue in rats and serum/right auricular appendage in man were found to be 6.4, 2.5, 5.6 and 2.8, respectively. These results confirm that evolving-pattern analysis may provide a new sight for in-depth studies of biomarkers and diseases.

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Electrical stimulation of the spinal cord part of double-graft combinations generally elicited contractile responses in specific areas of the muscle cograft. This review presents these new agents and addresses their role in the treatment of candidiasis. EFFECTS OF NAOH USED IN TREATMENT OF SPECIMENS AND TUBERCLE BACILLI ON THE NUMBER OF BACTERIAL COLONY COUNTS. Intensive research has taken place in area of conversion of glycerol to numerous products. Easy peeling of the skin associated with keratotic areas was observed.

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Receptors for advanced glycation end-products targeting protect against hyperoxia-induced lung injury in mice. The nonglycosylated UT-A1 showed reduced localization in lipid rafts. To determine the feasibility and efficacy of endoscopic submucosal dissection(ESD) in treating early gastric cancer(EGC) and precancerous lesions in the remnant stomach of patients after gastrectomy. The social hygienic characteristics of deteriorated living environment in Surkhan-Daria area around the Tadjikistan aluminum factory are described.

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There are no controlled trials that show the benefit of treatment of subclinical hyperthyroidism, thus therapy at present needs to be determined by clinical judgement, aided by monitoring the patient to see if the low serum TSH level persists and assessing the presence or absence of other determinants of therapy such as an elevated serum triiodothyronine (T3) concentration, a multinodular goiter, or the appearance of overt symptoms. The laser speckle perfusion imaging (LSPI) system is a new, non-invasive technique for rapidly and reproducibly measuring tissue perfusion.

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However, PGE2 (0.1-100 nM) had no significant effects on the DNA synthesis of 5 days-suspension chondrocyte cultures. In this chapter, we describe the use of the Na/I symporter as a reporter gene, associated with (124)I-NaI as a radiotracer, to monitor the anatomical localization, as well as the propagation, of oncolytic viruses using dedicated, preclinical positron emission tomography scanners. Information was obtained from national databases, published reports, scholarly articles, and association websites. Control blood smears from uninfected hosts revealed fluorescence only in the leukocytes of mammalian blood or in nuclei of leukocytes and erythrocytes of avian blood.

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Therapeutic approach in arterial hypertension with renal artery stenosis Anatomical changes at the level of the primary synapse in neuropathic pain: evidence from the spinal trigeminal nucleus. Different methods of delivering chemotherapy have been compared in a medium scale operational control programme.

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Hemodialysis urea rebound: the effect of increasing dialysis efficiency. They have been used effectively to control preharvest and postharvest phytophagous insects and as insect repellents for biting flies and for home and garden insects.

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Review of prospectively collected data from 416 CEs identified 27 tumors in 26 patients. In smokers it is associated with higher degrees of cigarette dependence but not with a greater motivation to stop smoking.

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Identifying prognostic factors for drug rash with eosinophilia and systemic symptoms (DRESS). Novel diagnostic model for the deficient and excess pulse qualities.