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ACh receptor patches were also seen in central regions of some myotomes and these were usually aligned in patterns which resembled the course of nerve fibres. This latency difference was attributed to the time of the wave travelling along the basilar membrane. This retrospective study (1) compared the outcome of root canal treatment performed by an endodontist using 1 of 2 different protocols and (2) evaluated the influence of factors affecting outcome. To facilitate the study of the biochemistry of these modified nucleosides we have raised monoclonal antibodies to N6-(delta 2-isopentenyl)adenosine and N6-(4-hydroxy-3-methyl-but-2-enyl)adenosine. To assess the safety, immunogenicity and lot consistency of a liquid hexavalent combined vaccine (DTaP-IPV-PRP approximately T-HBs, HEXAVAC) (Sanofi-Pasteur MSD, France) administered to infants at two, four and six months of age.

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ON THE UPTAKE AND PROPAGATION OF FRIEND LEUKEMIA VIRUS IN MACROPHAGES To study the anti-inflammatory mechanisms of total glycosides of Acanthopanax Giraldii (TGA). Our research showed that VPA rats spent more time in the part with an unknown animal and less time in the central part of a three chamber sociability test apparatus than control animals. Protein kinases (Ser/Thr and Tyr) play a key role in signal transduction pathways.

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Nor could the association of CaM to ER which did not differ among all cell lines. Control of von Willebrand factor multimer size and implications for disease. Additionally, we find that the X chromosome is more favorable to the fixation of alleles that are beneficial when maternally derived. Long-term treatment with cis-dichlorodiammineplatinum(II)-vinblastine-bleomycin: possible association with severe coronary artery disease. The atypical neurons consisted of six types: (1) inverted, (2) tumbled, (3) bipolar, (4) V-shaped, (5) hook-shaped, and (6) superficial polymorphic.

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This review outlines the steps for obtaining relative binding constants for drugs from footprinting data. We show in this paper how simple considerations about bio-arrays images lead to a peak segmentation allowing the genes activity analysis. Knockdown of fos-1 or jun-1 blocks dilation of the distal spermathecal valve, a critical step for the entry of mature oocytes into the spermatheca for fertilization. In addition, TPA reversed the HGF effect in both normal hepatocytes and FaO HCC cells. The mean number of cigarettes smoked daily and smoking duration significantly correlated positively with sperm Smac/DIABLO, caspase-9 activity, the percent of DNA fragmentation and seminal plasma cotinine, and significantly correlated negatively with tested semen variables.

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ANATOMO-PATHOLOGIC ASPECTS AND PATHOGENETIC CONSIDERATIONS ON PERITONITIS DUE TO MECONIUM Diabetes and its related microvascular complications like diabetic retinopathy (DR) are showing increased prevalence in India.

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Chromosome preparations were made from these patients after informed consent was obtained. Eleven patients were admitted to hospital for further treatment and observation, and 7 were treated in the Accident and Emergency Department. Recent data about the genetic transmission and pathogenesis of the hereditary motor and sensory neuropathies (HMSN) are discussed.

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A cell-associated mannose-resistant hemagglutinating factor (HAF) was extracted from enteroinvasive Escherichia coli (EIEC) serotype O124:H- by sonication. To elucidate the issue of the adaptive role of intraspecific divergence, the changes in the physicochemical properties of amino acids in the course ofcladogenesis (MM01 model of the TreeSAAP 3.2 package) were analyzed in this work using as an example the nucleotide sequences of the cytochrome b gene in some species of northern animals (lemmings, redbacked voles, chipmunks, flying squirrels, ermines). The present series describes a group of adults with left-to-right shunts including partial anomalous pulmonary venous return (PAPVR) and/or an atrial septal defect (ASD) evaluated with ECG-gated 128-slice multidetector computed tomography (MDCT). The packaging of DNA into strings of nucleosomes is one of the features that allows eukaryotic cells to tightly regulate gene expression. Exercise training should be recommended for patients with stable New York Heart Association class II to III heart failure.

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Many of the studies on emerging epidemics (such as SARS and pandemic flu) use mass action models to estimate reproductive numbers and the needed control measures. The results indicate that subacute acid base changes do not affect proinsulin cleavage. Magnetic resonance imaging (MRI) studies have shown abnormalities limited to T2-weighted high signal intensity in the posterior columns.

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The levels of IL-1alpha, 1beta, 6, 8, and 10 in synovial fluid were examined, using a high sensitivity enzyme-linked immunosorbent assay (ELISA) test kit (Pierce Biotechnology, Inc., Rockford, IL, USA) to determine whether these cytokines could be used as markers of enhanced periprosthetic osteolysis, leading to aseptic loosening of total/partial hip arthroplasty or revision surgery. During the 19th century, craniometric studies suggested that the Botocudo resembled more the Paleoamerican population of Lagoa Santa than typical Native Americans groups. Mechanisms responsible for allergic-like reactions following administration of radiographic contrast media (RCM) are unclear.

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We describe two patients with pityriasis rubra pilaris in whom hypertriglyceridemia developed following the oral administration of high-dose vitamin A (retinol). We have previously demonstrated that renal cortical collecting duct cells (RCCD(1)), responded to hypotonic stress with a rapid activation of regulatory volume decrease (RVD) mechanisms. The effects of suctioning techniques on the distal tracheal mucosa in intubated low birth weight infants. On the basis of these data, we suggest that cycling between the trans-Golgi cisterna and the trans-Golgi network of galT is signal mediated.

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Pharmaceutical, cosmetic and personal care products that are specifically formulated for application onto human external mucosae can occasionally induce undesirable local or systemic side-effects. Temporal change in the genetic structure between and within cohorts of a marine fish, Diplodus sargus, induced by a large variance in individual reproductive success.

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We have previously shown that Plasmodium falciparum recombinant antigens PfEB200, R23, and Pfi72 inhibit opsonization of infected erythrocytes by hyperimmune Saimiri sera, indicating that they contain target epitopes involved in the phagocytosis of infected erythrocytes. Dose-limiting toxicity of CP-547,632 at 250 mg consisted of diarrhea and rash.

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HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier. Twice weekly 5-azacytidine infusion in dissmeinated metastatic cancer: a phase II study. In contrast, 5 alpha-dihydrotestosterone concentrations were lower than normal. In the present study, we characterize, in detail, the function of zebrafish RNases in various steps in the process of angiogenesis. The needs of developing countries: a challenge to the illustration services.

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Noninvasive approaches, meticulous chronic instrumentation for the recording of multiple respiratory indices, and correlations with brain studies performed after physiological manipulations in vivo can all be employed to get to some understanding of the maturation of respiratory control in the mammal. Photoreaction of methyl 4-O-azidocarbonyl-2,3,6-trideoxy-L-hex-2-enopyranosides, followed by aziridine opening, leads to 3-amino-3-N-,4-O-carbonyl-2,3,6-trideoxy precursors to the aminosugar methyl glycosides. Serum from patients with S bovis endocarditis produced eight different precipitin arcs.

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To preliminarily determine the effectiveness of corticosteroid therapy on the central nervous system symptoms of a child with ataxia-telangiectasia in whom neurological signs improved when, occasionally, he was given betamethasone to treat asthmatic bronchitis attacks. Genes of the Wnt and Frizzled class, expressed in HNSCC tissue and cell lines, have an established role in cell morphogenesis and differentiation, and also they have oncogenic properties. Anisotropic expansion of an M2L4 coordination capsule: host capability and frame rearrangement.

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The MAPK inhibitors SB-203580, SB-202190 and SB-242235 were examined in HEK293 cells expressing recombinant P2X(7) receptors and in THP-1 cells expressing native human P2X(7) receptors using a range of experimental approaches. Understanding the dimensions of pathways of introduction of alien plants is important for regulating species invasions, but how particular pathways differ in terms of post-invasion success of species they deliver has never been rigorously tested. We examined the association between exposure to environmental PAHs and IR in Korean urban elderly adults controlling for major risk factors that contribute to an increase in IR. However, endotoxin-exposed PCU particles induced significantly less TNFalpha and IL-1beta than endotoxin-exposed xUHMWPE particles.

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The bioactive compounds including phenolics may be responsible for the chemopreventive effects. Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis. Baseline and posttreatment evaluations of pain using a verbal analogue scale, the Brief Pain Inventory, and the status of the MTrP as determined by digital palpation. Exact parametric confidence intervals for Bland-Altman limits of agreement. Here, we investigated the effect of BBR on the transcriptional activity and the protein expression of p53 in p53-positive (wild- type, MCF7 cells) and p53-negative (mutant, MDA-MB231 cells) human breast cancer cells.

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Reactive electrophilic oxylipins: pattern recognition and signalling. Diastolic dysfunction in hypertrophic cardiomyopathy (HCM) is accompanied by augmented left ventricular (LV) end-diastolic pressure, above all in the presence of LV outflow tract (LVOT) obstruction.

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Elevated mast cell tryptase in cerebrospinal fluid of multiple sclerosis patients. Inhibition of HIV-1 replication in alveolar macrophages by adenovirus gene transfer vectors. Excessive endogenous glucose production contributes to fasting hyperglycemia in diabetes. The calf muscles in the patients were enlarged both relative to the quadriceps and absolutely when related to the cross-sectional area of the femur used as an index of stature.

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The study involved both self-measuring instruments and a standardized psychiatric interview. A spectrophotometric study of the binding of Cu(II) ions to ATP.

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We hypothesize that a biodegradable and biocompatible acellular scaffold such as small intestine submucosa, which contains entrapped growth factors, may stimulate disc cells to synthesize extracellular matrix, thereby arresting the degeneration, or even promoting the regeneration, of the disc. Of 26 patients, there were 13 bilateral complete cleft lip and palate, 9 bilateral incomplete cleft lip and 4 mixed cleft lip with unilateral complete cleft palate.

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Abnormal maturation of elastic fibres in the atherosclerotic intima. Histopathologic analysis confirmed the protective effect of melatonin against CCH-induced morphologic alterations. Moreover, infanticide can increase the reproductive success of the aggressor by killing the offspring of competitors and thereafter mating with the victimized females.

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Negative screening result, (false) positive screening result, medical consumption and number needed to screen. Structure of antibody hypervariable loops reproduced by a conformational search algorithm. In the last few years public interest in the care of severely ill and dying patients has been growing.

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Following the incubation in an ionic protein solution, proteins adsorbed to the cell surface were insolubilized by repeated treatment with low ionic isotonic surcose. Presently retroperitoneal lymphadenectomy combined with intensive chemotherapy seems to be the treatment of choice for metastatic testicular carcinomas.

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Photonic bands estimated from the group delay characteristics corresponded to calculated ones. In situ analysis of protein S-glutathionylation in lung tissue using glutaredoxin-1-catalyzed cysteine derivatization. Individual quit strategies are not consistently found to be associated with higher hazard levels. FUNCTIONAL EVALUATION OF THE HEART IN HEART DISEASE PATIENTS BY MEANS OF MAXIMAL AEROBIC WORK

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Chronic inflammation should be regarded as a common comorbid condition in CKD and especially in dialysis patients. ENHANCED RETICULOENDOTHELIAL PHAGOCYTIC ACTIVITY IN MYELOPROLIFERATIVE DISEASES. We present experimental and theoretical results showing that room temperature Co deposition on fully hydroxylated clean sapphire (alpha-Al2O3) produces a surface chemical reaction that leads to laminar growth, despite a large mismatch in lattice constants.

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A number of independent groups using different methods of detection have shown that p53 alterations are associated with more aggressive tumor biologic factors and a poorer prognosis in breast cancer patients. Morphological features of heart grafts, recipient spleens and lymph nodes. This is thought to be due to continued progression of amyloidosis occasioned by longer survival in the present series. A synthetic route to 2,3-difluorosuccinates has been developed through erythro- and threo- 1,2-difluoro-1,2-diphenylethane which involved the oxidation of the aryl rings to generate the corresponding 2,3-difluorosuccinic acids. The importance of adherence to these guidelines by oral health researchers is emphasized.

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Analysis of the frequency components of the velocity wave was performed, and significantly higher frequency components up to 100 Hertz were found in the turbulent cases compared to the laminar ones. The study has demonstrated that local data is more timely and of greater detail than that available nationally. We determined that gustatory perception of sweetness is both necessary and sufficient to suppress starvation-induced sleep loss when animals encounter nutrient-poor food sources. Cessation of estrogen therapy was followed by a rapid induction of bone loss, indicating that estrogen blocks the activation and utilization of mature osteoclasts without depleting the bone microenvironment of osteoclast precursors and mature, inactive osteoclasts.

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The relationships between cold temperatures and cardio-respiratory mortality in the elderly are well documented. Epidermal expression of serine protease, neuropsin (KLK8) in normal and pathological skin samples. Clustering of carbohydrate-binding sites in the receptor tetramer is believed to be critical for targeting of pathogen glycans, but the arrangement of these sites remains poorly understood. An intact laminated layer is important for the establishment of secondary Echinococcus multilocularis infection. Plants resulting from a cross between both mutants (atnrt2.1-1 x atnar2.1-1) showed a phenotype like that of the atnar2.1-1 mutant when grown in 0.5 mm nitrate.

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The results of the study on the composition, properties and antibiotic sensitivity of pathogenic microbes isolated from purulent wounds of the soft tissues of patients treated in the Institute clinic in 1977-1980 are presented. For the medical mission to Jamaica, medications are often purchased or donated from various locations, including retail pharmacies, drug wholesalers, medication drives, pharmaceutical companies, and medication assistance programmes specific to medical missions.

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Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties. Use of ceftriaxone (rocefin) in the prevention of postoperative infections in interventions with prostheses grafts in vascular surgery Costunolide induced apoptosis of platinum-resistant cells in a time- and dose-dependent manner and suppressed tumor growth in SKOV3(PT)-bearing mouse model. Because the hippocampal place cell system is essential for long-term spatial memory, we tested the hypothesis that zif268 is required for long-term stability of hippocampal place cell representations by recording CA1 place cells in mice lacking zif268.

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Patients with acute versus chronic IHD displayed differences in changes of hemocirculatory parameters in the process of treatment. It is recognized that adenotonsillar hypertrophy leads to muscular and functional changes in face, and that adenotonsillectomy is associated to improvement in this condition.

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In contrast to this, release of the obstruction on ED 15 in Group 2 resulted in almost normal gut morphology at ED 19. IVL is a rare and potentially underdiagnosed neoplastic condition of smooth muscle origin that may result in significant morbidity when extrauterine vasculature or organs are involved. A teratogen test system is based on disruption of elongation between 24 and 48 hr after wetting of the cysts.

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Whole body somatostatin receptor scintigraphy showed tracer accumulation in the liver lesions, with no extrahepatic tumour, possibly the primary origin. In FY82, per capita allocations to genetics and sickle cell programs were not significantly different between states that remained eligible in FY83 and those that became ineligible. Distribution of lymphocytes from normal cattle and cattle with different forms of lympholeukemia according to DNA content We subsequently assessed the impact of ABCB1 polymorphisms on intracellular vincristine accumulation. PA might be misinterpreted clinically and pathologically as a malignant tumor.

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N-terminal sequencing of processed phenol oxidase revealed 11 kDa propeptide instead of in-silico predicted 6 kDa polypeptide. All the laser-treated wounds and the untreated control wounds healed in the same way within the same period of time. Therefore it is concluded that discocytes I represent the initial stage of erythrocytes transforming under banking conditions. Furthermore, some rare syndromes with glomerular involvement, in which molecular defects have been recently identified, are briefly described. Decreased functional connectivity was found between the left amygdala and left dorsolateral prefrontal cortex.